• Card 14 / 27: Circulating chemicals such as alcohol, ipecac, etc. stimulate this region in the floor of the fourth ventricle because:
    A.) There is no blood-brain barrier so substances have direct access to appropriate chemoreceptors.
    B.) The substances circulate through the ventricular system and directly stimulate the vomiting center.
    C.) They cause a decrease in threshold for neural circuits.
    D.) Visceral afferents in the tractus solitarius are hyperexcitable.

    Answer:
    A.) There is no blood-brain barrier so substances have direct access to appropriate chemoreceptors.

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Explanation:

Direct access to the CNS through an incomplete blood brain barrier in the region of the area postrema (arrow) is how some drugs are able to affect the CNS.

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Ch 06: Head Somatic & Visceral Sensory Systems

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Attribution:  Stephen C. Voron, M.D., Suzanne S. Stensaas, Ph.D. , Department of Neurobiology and Anatomy, University of Utah, School of Medicine, Salt Lake City, Utah 84132, http://library.med.utah.edu/kw/hyperbrain
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