• Card 14 / 34: Canine dysautonomia is a rare condition in dogs associated with degeneration of autonomic nervous system. What is the best way to diagnose this disease?
    A) Run a myasthenia gravis antibody titer test
    B) Fecal exam and urinalysis since these dogs have diarrhea and dysuria
    C) Barium contrast study radiograph
    D) Schmirmer tear test and pharmacologic testing of the pupils (i.e. provocative ocular test using Pilocarpine) to determine mydriasis
    E) Run a thyroid panel

    Answer:
    D) Schmirmer tear test and pharmacologic testing of the pupils (i.e. provocative ocular test using Pilocarpine) to determine mydriasis

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Explanation:

Dilute pilocarpine (0.05% ophthalmic solution) results in rapid pupillary constriction in dogs with dysautonomia because of supersensitivity of the denervated muscle to cholinergic drugs. The prognosis is grave.

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Clin Sci I - GI Twedt quiz

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