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There was still intermittent warfare and civil uprisings. The third Ming emperor, Ch'eng-tsu, came to power by overthrowing his nephew, after three years of civil war, but he rebuilt Peking and reconstructed the silted-up Grand Canal, thus allowing grain and textiles to come to the city from the rich southeast. He bullied Japan into nominal vassalage for the first time. In the middle of the century the emperor Ying-tsung (era name - Tien-shun) was taken captive and his court slaughtered by a Mongol raider, Esen. Rural problems also led to a number of rebellions, chiefly in the central and southeastern China, leading to a million deaths. (Ref. 101 , 8 )

Japan

Although organization and administration was sometimes neglected and chaotic, many of the dictators of the Ashikaga Shogunate were patrons of the arts and collected pieces that are prizes of collectors today. Local rulers of wide territories were called daimyos , meaning "feudal lords" and their subordinate soldiery were samurai , a word originally simply meaning "attendant". In the civil wars which raged throughout Japan, sometimes an entire clan family would be killed off and then their remaining fighting retainers would become masterless samurai or- ronin (wave-men). Some of these became pirates, terrorizing the coast of China and even the Philippines. (Ref. 12 ) In 1428, transport workers struck in protest against high prices and they, backed by farmers, rioted in the streets and wrecked warehouses, temples and houses. (Ref. 222 )

Towns developed, eventually becoming the modern cities of Osaka, Kobe and Fukuoka. Kyoto was the undisputed political and cultural capital. This was still a thoroughly Buddhist age in Japan, but intellectual life began to free itself from the bonds of religion. The Ashikaga power began to decline early in the century and the Onin War (1467-77) began a hundred years of strife between the feudal lords. (Ref. 119 , 12 )

Korea

The new Yi Dynasty was dominated by the Chinese and there was a suppression of Buddhism. Japanese pirate raids subsided somewhat and Korea had a period of great prosperity and cultural development. King Sejong (1419-1451) was a great patron of learning. It was at this time that the native phonetic script called "Onmum" was introduced and it is possible that the movable metal printing characters mentioned above were actually developed in Korea. (Ref. 233 , 260 )

Southeast asia

The Chinese Ming occupied Annam (Vietnam), through their navy, from 1407 to 1427, but then met resistance and finally allowed the region its independence in 1428. A Lao tribal monarch established the Laotian Kingdom of Lan Xang in mid-century. This included present day Laos and much of northern and eastern Thailand. The Siamese (Thai), under King Trailok, had centralized bureaucracy and a codified system of law. They ravaged Angkor in 1431 and took over a great part of the southern Khmer Empire, leaving them only what is now the general area of Cambodia and which was then called "Kambuja". After the sacking of Angkor the Siamese went home with as much loot as they could carry and when they returned for more a year later the city, where once there had been a million people, was deserted. No one knows where the people went, but through neglect the huge reservoirs, canals, roads and bridges all gave way to the jungle. (Ref. 8 , 101 , 176 ) Braudel (Ref. 260 ) says that the Siamese attacks upset the daily life and agriculture so that the rice field water cleared, allowing the malaria carrying mosquitoes to thrive and that the disease apparently decimated the population.

Northern Burma was under the Shan power while southern Burma was under the Mon (Pegu). The new Vietnamese kingdom of Dai-Viet gradually absorbed Champa territory, annexing its capital, Vijaya, in 1471. (Ref. 8 )

Since the Moluccas Islands and Malay, along with Ceylon, were the source of almost all spices, Malacca became an international port, shipping to China and the Malabar coast of India from where Arabs, Indians and Persians took over for further distribution. Built in a dismal swamp almost inaccessible by land, Malacca had been of no importance except as a pirate storage headquarters until in this and the preceding century it became a port for peaceable shipping. (Ref. 279 ) The men of Islam overthrew the old Majapahit Empire and their religion, which had been introduced into the Malayan archipelago from India in the 10th century, now finally became dominant as the Hindus were driven to Bali and a few other islands. (Ref. 8 , 68 )

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Questions & Answers

how does Neisseria cause meningitis
Nyibol Reply
what is microbiologist
Muhammad Reply
what is errata
Muhammad
is the branch of biology that deals with the study of microorganisms.
Ntefuni Reply
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Mercy Reply
studies of microbes
Louisiaste
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Ziyad Reply
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Bacteria doesn't produce energy they are dependent upon their substrate in case of lack of nutrients they are able to make spores which helps them to sustain in harsh environments
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Muhamad
they make spores
Louisiaste
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the significance of food webs for disease transmission
Abreham
food webs brings about an infection as an individual depends on number of diseased foods or carriers dully.
Mark
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Esinniobiwa Reply
Assimilatory nitrate reduction is a process that occurs in some microorganisms, such as bacteria and archaea, in which nitrate (NO3-) is reduced to nitrite (NO2-), and then further reduced to ammonia (NH3).
Elkana
This process is called assimilatory nitrate reduction because the nitrogen that is produced is incorporated in the cells of microorganisms where it can be used in the synthesis of amino acids and other nitrogen products
Elkana
Examples of thermophilic organisms
Shu Reply
Give Examples of thermophilic organisms
Shu
advantages of normal Flora to the host
Micheal Reply
Prevent foreign microbes to the host
Abubakar
they provide healthier benefits to their hosts
ayesha
They are friends to host only when Host immune system is strong and become enemies when the host immune system is weakened . very bad relationship!
Mark
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faisal Reply
cell is the smallest unit of life
Fauziya
cell is the smallest unit of life
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Innocent
cell is the structural and functional unit of life
Hasan
is the fundamental units of Life
Musa
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Micheal Reply
There are nothing like emergency disease but there are some common medical emergency which can occur simultaneously like Bleeding,heart attack,Breathing difficulties,severe pain heart stock.Hope you will get my point .Have a nice day ❣️
_Adnan
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Innocent
I think infection prevention and control is the avoidance of all things we do that gives out break of infections and promotion of health practices that promote life
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en français
Adama
which site have a normal flora
ESTHER Reply
Many sites of the body have it Skin Nasal cavity Oral cavity Gastro intestinal tract
Safaa
skin
Asiina
skin,Oral,Nasal,GIt
Sadik
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all
Tesfaye
by fussion
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Shelly Reply
part of a tissue or an organ being wounded or bruised.
Wilfred
what term is used to name and classify microorganisms?
Micheal Reply
Binomial nomenclature
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Source:  OpenStax, A comprehensive outline of world history. OpenStax CNX. Nov 30, 2009 Download for free at http://cnx.org/content/col10595/1.3
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