• Card 8 / 13: This is a picture is of the brain of a patient with Huntington's Disease. Microscopically you would see:
    A.) Loss of melanin filled cells in the striatum.
    B.) Loss of cells in the caudate and putamen.
    C.) Degenerating axons from the substantia nigra.
    D.) All of the above.

    Answer:
    B.) Loss of cells in the caudate and putamen.

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Explanation:

Huntington's disease is characterized by a loss of the medium sized cells in the caudate and putamen. Cell loss also occurs in the cerebral cortex. This is an autosomal dominant disease appearing in the 30s or 40s with abnormal jerking movements and mental deterioration.Click on the numbers to see a motion sequence of Huntington's disease: 22756 to 22884*.

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Neuroanatomy 12 The Basal Ganglia

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Attribution:  Stephen C. Voron, M.D., Suzanne S. Stensaas, Ph.D. , Department of Neurobiology and Anatomy, University of Utah, School of Medicine, Salt Lake City, Utah 84132, http://library.med.utah.edu/kw/hyperbrain
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