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References

“Vitamin E and Health,” Nutrition Source, Harvard School of Public Health, http://www.hsph.harvard.edu/nutritionsource/vitamin-e/ (accessed May 1, 2013).

Stan Reents. “Don’t Underestimate the Power of Suggestion,” athleteinme.com, http://www.athleteinme.com/ArticleView.aspx?id=1053 (accessed May 1, 2013).

Ankita Mehta. “Daily Dose of Aspiring Helps Reduce Heart Attacks: Study,” International Business Times, July 21, 2011. Also available online at http://www.ibtimes.com/daily-dose-aspirin-helps-reduce-heart-attacks-study-300443 (accessed May 1, 2013).

The Data and Story Library, http://lib.stat.cmu.edu/DASL/Stories/ScentsandLearning.html (accessed May 1, 2013).

M.L. Jacskon et al., “Cognitive Components of Simulated Driving Performance: Sleep Loss effect and Predictors,” Accident Analysis and Prevention Journal, Jan no. 50 (2013), http://www.ncbi.nlm.nih.gov/pubmed/22721550 (accessed May 1, 2013).

“Earthquake Information by Year,” U.S. Geological Survey. http://earthquake.usgs.gov/earthquakes/eqarchives/year/ (accessed May 1, 2013).

“Fatality Analysis Report Systems (FARS) Encyclopedia,” National Highway Traffic and Safety Administration. http://www-fars.nhtsa.dot.gov/Main/index.aspx (accessed May 1, 2013).

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“America’s Best Small Companies,” http://www.forbes.com/best-small-companies/list/ (accessed May 1, 2013).

U.S. Department of Health and Human Services, Code of Federal Regulations Title 45 Public Welfare Department of Health and Human Services Part 46 Protection of Human Subjects revised January 15, 2009. Section 46.111:Criteria for IRB Approval of Research.

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Lori Alden, “Statistics can be Misleading,” econoclass.com, http://www.econoclass.com/misleadingstats.html (accessed May 1, 2013).

Maria de los A. Medina, “Ethics in Statistics,” Based on “Building an Ethics Module for Business, Science, and Engineering Students” by Jose A. Cruz-Cruz and William Frey, Connexions, http://cnx.org/content/m15555/latest/ (accessed May 1, 2013).

Chapter review

A poorly designed study will not produce reliable data. There are certain key components that must be included in every experiment. To eliminate lurking variables, subjects must be assigned randomly to different treatment groups. One of the groups must act as a control group, demonstrating what happens when the active treatment is not applied. Participants in the control group receive a placebo treatment that looks exactly like the active treatments but cannot influence the response variable. To preserve the integrity of the placebo, both researchers and subjects may be blinded. When a study is designed properly, the only difference between treatment groups is the one imposed by the researcher. Therefore, when groups respond differently to different treatments, the difference must be due to the influence of the explanatory variable.

“An ethics problem arises when you are considering an action that benefits you or some cause you support, hurts or reduces benefits to others, and violates some rule.” Andrew Gelman, “Open Data and Open Methods,” Ethics and Statistics, http://www.stat.columbia.edu/~gelman/research/published/ChanceEthics1.pdf (accessed May 1, 2013). Ethical violations in statistics are not always easy to spot. Professional associations and federal agencies post guidelines for proper conduct. It is important that you learn basic statistical procedures so that you can recognize proper data analysis.

Design an experiment. Identify the explanatory and response variables. Describe the population being studied and the experimental units. Explain the treatments that will be used and how they will be assigned to the experimental units. Describe how blinding and placebos may be used to counter the power of suggestion.

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Discuss potential violations of the rule requiring informed consent.

  1. Inmates in a correctional facility are offered good behavior credit in return for participation in a study.
  2. A research study is designed to investigate a new children’s allergy medication.
  3. Participants in a study are told that the new medication being tested is highly promising, but they are not told that only a small portion of participants will receive the new medication. Others will receive placebo treatments and traditional treatments.
  1. Inmates may not feel comfortable refusing participation, or may feel obligated to take advantage of the promised benefits. They may not feel truly free to refuse participation.
  2. Parents can provide consent on behalf of their children, but children are not competent to provide consent for themselves.
  3. All risks and benefits must be clearly outlined. Study participants must be informed of relevant aspects of the study in order to give appropriate consent.
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Source:  OpenStax, Introductory statistics. OpenStax CNX. May 06, 2016 Download for free at http://legacy.cnx.org/content/col11562/1.18
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