Question 31 / 32:  A 55 year-old man with chronic hepatitis C related cirrhosis presents to the Liver Transplant Clinic for evaluation. He has had a large esophageal variceal bleed in the past and is now bothered by ascites.

Which of the following best characterizes this patient’s circulation?

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Explanation:

Cirrhotic patients have a hyperdynamic cardiac response to low peripheral vascular resistance. Portal hypertension (present given history of esophageal varices) develops due to resistance to blood flow in the liver and a high rate of blood flow in the splanchnic circulation.

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Gastrointestinal Pathophysiology Self-Assessment

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Attribution:  Laurence Scott Bailen, Tamsin Knox, Paul Abourjaily, Fredric D. Gordon,Marshall Kaplan,Andrew G. Plaut. PPY 222 Gastrointestinal Pathophysiology, Spring 2007. (Tufts University OpenCourseWare), http://ocw.tufts.edu/Course/47 (Accessed 3 May, 2014). License: Creative Commons BY-NC-SA
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