# 1.1 Medical imaging and diagnostics  (Page 3/9)

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## Phet explorations: simplified mri

Is it a tumor? Magnetic Resonance Imaging (MRI) can tell. Your head is full of tiny radio transmitters (the nuclear spins of the hydrogen nuclei of your water molecules). In an MRI unit, these little radios can be made to broadcast their positions, giving a detailed picture of the inside of your head.

## Section summary

• Radiopharmaceuticals are compounds that are used for medical imaging and therapeutics.
• The process of attaching a radioactive substance is called tagging.
• [link] lists certain diagnostic uses of radiopharmaceuticals including the isotope and activity typically used in diagnostics.
• One common imaging device is the Anger camera, which consists of a lead collimator, radiation detectors, and an analysis computer.
• Tomography performed with $\gamma$ -emitting radiopharmaceuticals is called SPECT and has the advantages of x-ray CT scans coupled with organ- and function-specific drugs.
• PET is a similar technique that uses ${\beta }^{+}$ emitters and detects the two annihilation $\gamma$ rays, which aid to localize the source.

## Conceptual questions

In terms of radiation dose, what is the major difference between medical diagnostic uses of radiation and medical therapeutic uses?

One of the methods used to limit radiation dose to the patient in medical imaging is to employ isotopes with short half-lives. How would this limit the dose?

## Problems&Exercises

A neutron generator uses an $\alpha$ source, such as radium, to bombard beryllium, inducing the reaction ${}^{4}\text{He}+{}^{9}\text{Be}\to {}^{\text{12}}\text{C}+n$ . Such neutron sources are called RaBe sources, or PuBe sources if they use plutonium to get the $\alpha$ s. Calculate the energy output of the reaction in MeV.

5.701 MeV

Neutrons from a source (perhaps the one discussed in the preceding problem) bombard natural molybdenum, which is 24 percent ${}^{\text{98}}\text{Mo}$ . What is the energy output of the reaction ${}^{\text{98}}\text{Mo}+n\to {}^{\text{99}}\text{Mo}+\gamma$ ? The mass of ${}^{\text{98}}\text{Mo}$ is given in Appendix A: Atomic Masses , and that of ${}^{\text{99}}\text{Mo}$ is 98.907711 u.

The purpose of producing ${}^{\text{99}}\text{Mo}$ (usually by neutron activation of natural molybdenum, as in the preceding problem) is to produce ${}^{\text{99m}}\text{Tc.}$ Using the rules, verify that the ${\beta }^{-}$ decay of ${}^{\text{99}}\text{Mo}$ produces ${}^{\text{99m}}\text{Tc}$ . (Most ${}^{\text{99m}}\text{Tc}$ nuclei produced in this decay are left in a metastable excited state denoted ${}^{\text{99m}}\text{Tc}$ .)

${}_{\text{42}}^{\text{99}}{\text{Mo}}_{\text{57}}\to {}_{\text{43}}^{\text{99}}{\text{Tc}}_{\text{56}}+{\beta }^{-}+{\overline{v}}_{e}$

(a) Two annihilation $\gamma$ rays in a PET scan originate at the same point and travel to detectors on either side of the patient. If the point of origin is 9.00 cm closer to one of the detectors, what is the difference in arrival times of the photons? (This could be used to give position information, but the time difference is small enough to make it difficult.)

(b) How accurately would you need to be able to measure arrival time differences to get a position resolution of 1.00 mm?

[link] indicates that 7.50 mCi of ${}^{\text{99m}}\text{Tc}$ is used in a brain scan. What is the mass of technetium?

$1\text{.}\text{43}×{\text{10}}^{-9}\phantom{\rule{0.25em}{0ex}}\text{g}$

The activities of ${}^{\text{131}}\text{I}$ and ${}^{\text{123}}\text{I}$ used in thyroid scans are given in [link] to be 50 and $\text{70 μ}Ci$ , respectively. Find and compare the masses of ${}^{\text{131}}\text{I}$ and ${}^{\text{123}}\text{I}$ in such scans, given their respective half-lives are 8.04 d and 13.2 h. The masses are so small that the radioiodine is usually mixed with stable iodine as a carrier to ensure normal chemistry and distribution in the body.

(a) Neutron activation of sodium, which is 100% ${}^{\text{23}}\text{Na}$ , produces ${}^{\text{24}}\text{Na}$ , which is used in some heart scans, as seen in [link] . The equation for the reaction is ${}^{\text{23}}\text{Na}+n\to {}^{\text{24}}\text{Na}+\gamma$ . Find its energy output, given the mass of ${}^{\text{24}}\text{Na}$ is 23.990962 u.

(b) What mass of ${}^{\text{24}}\text{Na}$ produces the needed 5.0-mCi activity, given its half-life is 15.0 h?

(a) 6.958 MeV

(b) $5\text{.}7×{\text{10}}^{-\text{10}}\phantom{\rule{0.25em}{0ex}}\text{g}$

#### Questions & Answers

anyone know any internet site where one can find nanotechnology papers?
research.net
kanaga
Introduction about quantum dots in nanotechnology
what does nano mean?
nano basically means 10^(-9). nanometer is a unit to measure length.
Bharti
do you think it's worthwhile in the long term to study the effects and possibilities of nanotechnology on viral treatment?
absolutely yes
Daniel
how to know photocatalytic properties of tio2 nanoparticles...what to do now
it is a goid question and i want to know the answer as well
Maciej
characteristics of micro business
Abigail
for teaching engĺish at school how nano technology help us
Anassong
Do somebody tell me a best nano engineering book for beginners?
there is no specific books for beginners but there is book called principle of nanotechnology
NANO
what is fullerene does it is used to make bukky balls
are you nano engineer ?
s.
fullerene is a bucky ball aka Carbon 60 molecule. It was name by the architect Fuller. He design the geodesic dome. it resembles a soccer ball.
Tarell
what is the actual application of fullerenes nowadays?
Damian
That is a great question Damian. best way to answer that question is to Google it. there are hundreds of applications for buck minister fullerenes, from medical to aerospace. you can also find plenty of research papers that will give you great detail on the potential applications of fullerenes.
Tarell
what is the Synthesis, properties,and applications of carbon nano chemistry
Mostly, they use nano carbon for electronics and for materials to be strengthened.
Virgil
is Bucky paper clear?
CYNTHIA
carbon nanotubes has various application in fuel cells membrane, current research on cancer drug,and in electronics MEMS and NEMS etc
NANO
so some one know about replacing silicon atom with phosphorous in semiconductors device?
Yeah, it is a pain to say the least. You basically have to heat the substarte up to around 1000 degrees celcius then pass phosphene gas over top of it, which is explosive and toxic by the way, under very low pressure.
Harper
Do you know which machine is used to that process?
s.
how to fabricate graphene ink ?
for screen printed electrodes ?
SUYASH
What is lattice structure?
of graphene you mean?
Ebrahim
or in general
Ebrahim
in general
s.
Graphene has a hexagonal structure
tahir
On having this app for quite a bit time, Haven't realised there's a chat room in it.
Cied
what is biological synthesis of nanoparticles
what's the easiest and fastest way to the synthesize AgNP?
China
Cied
types of nano material
I start with an easy one. carbon nanotubes woven into a long filament like a string
Porter
many many of nanotubes
Porter
what is the k.e before it land
Yasmin
what is the function of carbon nanotubes?
Cesar
I'm interested in nanotube
Uday
what is nanomaterials​ and their applications of sensors.
how did you get the value of 2000N.What calculations are needed to arrive at it
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Good
Berger describes sociologists as concerned with
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