<< Chapter < Page Chapter >> Page >

Importance of white blood cell count

White blood cells (WBCs), also called leukocytes, are an integral part of the human immune system. These cells fight infections by attacking bacteria, viruses, and other foreign pathogens that invade the body. Having too many or too few white blood cells can indicate a blood disorder. Disorders affecting these cells often result in the body’s inability to eliminate or control infections. [1] Therefore, WBC count is of interest in clinical pathology and oncology.

A general WBC count can detect hidden infections within the body and alert doctors to undiagnosed medical conditions, such as autoimmune diseases, immune deficiencies, blood disorders, and cancer. However, a WBC count can indicate that there is a disease or condition affecting white blood cells, but it cannot determine the underlying cause. Several other tests may be performed at the same time or in follow up to an abnormal result to help make a diagnosis. One of these tests is a blood smear review. [2]

Blood smear test

A blood smear is a blood test used to look for abnormalities in red blood cells, WBCs, and platelets. The test provides information on the number and shape of these cells, which can help doctors diagnose certain medical conditions. There are five distinct subtypes of WBCs each with a unique nucleus morphology and function.

Blood smear example.

Figure 1. Example of stained blood smear slide. [3]

When stained, these morphological differences become more dramatic and can be seen in Table 1. Abnormalities in the shape or number of WBCs may be signs of the diseases mentioned above. Therefore, it is extremely important to obtain an accurate count of each subtype if any immune-linked disorders are suspected.

WBC Subtype Table.

Table 1. White blood cell subtypes, functions, and morphology. [1]

Accurate cell counting is a long and tedious process. Scientists and pathologists individually analyze each cell’s morphology through light microscopy. This can take up to several hours, time that a patient may not have. In addition, since it is a tiring process, observer fatigue can produce inaccurate results. We aim to quantify the morphological differences between the WBC subtypes and classify them in order to aid pathologists. An automatic isolation and classification algorithm would significantly decrease the time needed for a blood smear analysis, leading to faster, potentially life saving results.

Questions & Answers

anyone know any internet site where one can find nanotechnology papers?
Damian Reply
Introduction about quantum dots in nanotechnology
Praveena Reply
what does nano mean?
Anassong Reply
nano basically means 10^(-9). nanometer is a unit to measure length.
do you think it's worthwhile in the long term to study the effects and possibilities of nanotechnology on viral treatment?
Damian Reply
absolutely yes
how to know photocatalytic properties of tio2 nanoparticles...what to do now
Akash Reply
it is a goid question and i want to know the answer as well
characteristics of micro business
for teaching engĺish at school how nano technology help us
Do somebody tell me a best nano engineering book for beginners?
s. Reply
there is no specific books for beginners but there is book called principle of nanotechnology
what is fullerene does it is used to make bukky balls
Devang Reply
are you nano engineer ?
fullerene is a bucky ball aka Carbon 60 molecule. It was name by the architect Fuller. He design the geodesic dome. it resembles a soccer ball.
what is the actual application of fullerenes nowadays?
That is a great question Damian. best way to answer that question is to Google it. there are hundreds of applications for buck minister fullerenes, from medical to aerospace. you can also find plenty of research papers that will give you great detail on the potential applications of fullerenes.
what is the Synthesis, properties,and applications of carbon nano chemistry
Abhijith Reply
Mostly, they use nano carbon for electronics and for materials to be strengthened.
is Bucky paper clear?
carbon nanotubes has various application in fuel cells membrane, current research on cancer drug,and in electronics MEMS and NEMS etc
so some one know about replacing silicon atom with phosphorous in semiconductors device?
s. Reply
Yeah, it is a pain to say the least. You basically have to heat the substarte up to around 1000 degrees celcius then pass phosphene gas over top of it, which is explosive and toxic by the way, under very low pressure.
Do you know which machine is used to that process?
how to fabricate graphene ink ?
for screen printed electrodes ?
What is lattice structure?
s. Reply
of graphene you mean?
or in general
in general
Graphene has a hexagonal structure
On having this app for quite a bit time, Haven't realised there's a chat room in it.
what is biological synthesis of nanoparticles
Sanket Reply
what's the easiest and fastest way to the synthesize AgNP?
Damian Reply
types of nano material
abeetha Reply
I start with an easy one. carbon nanotubes woven into a long filament like a string
many many of nanotubes
what is the k.e before it land
what is the function of carbon nanotubes?
I'm interested in nanotube
what is nanomaterials​ and their applications of sensors.
Ramkumar Reply
how did you get the value of 2000N.What calculations are needed to arrive at it
Smarajit Reply
Privacy Information Security Software Version 1.1a
Berger describes sociologists as concerned with
Mueller Reply
Got questions? Join the online conversation and get instant answers!
Jobilize.com Reply

Get the best Algebra and trigonometry course in your pocket!

Source:  OpenStax, Automatic white blood cell classification using svm and neural networks. OpenStax CNX. Dec 16, 2015 Download for free at http://legacy.cnx.org/content/col11924/1.5
Google Play and the Google Play logo are trademarks of Google Inc.

Notification Switch

Would you like to follow the 'Automatic white blood cell classification using svm and neural networks' conversation and receive update notifications?