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Importance of white blood cell count

White blood cells (WBCs), also called leukocytes, are an integral part of the human immune system. These cells fight infections by attacking bacteria, viruses, and other foreign pathogens that invade the body. Having too many or too few white blood cells can indicate a blood disorder. Disorders affecting these cells often result in the body’s inability to eliminate or control infections. [1] Therefore, WBC count is of interest in clinical pathology and oncology.

A general WBC count can detect hidden infections within the body and alert doctors to undiagnosed medical conditions, such as autoimmune diseases, immune deficiencies, blood disorders, and cancer. However, a WBC count can indicate that there is a disease or condition affecting white blood cells, but it cannot determine the underlying cause. Several other tests may be performed at the same time or in follow up to an abnormal result to help make a diagnosis. One of these tests is a blood smear review. [2]

Blood smear test

A blood smear is a blood test used to look for abnormalities in red blood cells, WBCs, and platelets. The test provides information on the number and shape of these cells, which can help doctors diagnose certain medical conditions. There are five distinct subtypes of WBCs each with a unique nucleus morphology and function.

Blood smear example.

Figure 1. Example of stained blood smear slide. [3]

When stained, these morphological differences become more dramatic and can be seen in Table 1. Abnormalities in the shape or number of WBCs may be signs of the diseases mentioned above. Therefore, it is extremely important to obtain an accurate count of each subtype if any immune-linked disorders are suspected.

WBC Subtype Table.

Table 1. White blood cell subtypes, functions, and morphology. [1]

Accurate cell counting is a long and tedious process. Scientists and pathologists individually analyze each cell’s morphology through light microscopy. This can take up to several hours, time that a patient may not have. In addition, since it is a tiring process, observer fatigue can produce inaccurate results. We aim to quantify the morphological differences between the WBC subtypes and classify them in order to aid pathologists. An automatic isolation and classification algorithm would significantly decrease the time needed for a blood smear analysis, leading to faster, potentially life saving results.

Questions & Answers

where we get a research paper on Nano chemistry....?
Maira Reply
what are the products of Nano chemistry?
Maira Reply
There are lots of products of nano chemistry... Like nano coatings.....carbon fiber.. And lots of others..
learn
Even nanotechnology is pretty much all about chemistry... Its the chemistry on quantum or atomic level
learn
Google
da
no nanotechnology is also a part of physics and maths it requires angle formulas and some pressure regarding concepts
Bhagvanji
Preparation and Applications of Nanomaterial for Drug Delivery
Hafiz Reply
revolt
da
Application of nanotechnology in medicine
what is variations in raman spectra for nanomaterials
Jyoti Reply
I only see partial conversation and what's the question here!
Crow Reply
what about nanotechnology for water purification
RAW Reply
please someone correct me if I'm wrong but I think one can use nanoparticles, specially silver nanoparticles for water treatment.
Damian
yes that's correct
Professor
I think
Professor
Nasa has use it in the 60's, copper as water purification in the moon travel.
Alexandre
nanocopper obvius
Alexandre
what is the stm
Brian Reply
is there industrial application of fullrenes. What is the method to prepare fullrene on large scale.?
Rafiq
industrial application...? mmm I think on the medical side as drug carrier, but you should go deeper on your research, I may be wrong
Damian
How we are making nano material?
LITNING Reply
what is a peer
LITNING Reply
What is meant by 'nano scale'?
LITNING Reply
What is STMs full form?
LITNING
scanning tunneling microscope
Sahil
how nano science is used for hydrophobicity
Santosh
Do u think that Graphene and Fullrene fiber can be used to make Air Plane body structure the lightest and strongest. Rafiq
Rafiq
what is differents between GO and RGO?
Mahi
what is simplest way to understand the applications of nano robots used to detect the cancer affected cell of human body.? How this robot is carried to required site of body cell.? what will be the carrier material and how can be detected that correct delivery of drug is done Rafiq
Rafiq
if virus is killing to make ARTIFICIAL DNA OF GRAPHENE FOR KILLED THE VIRUS .THIS IS OUR ASSUMPTION
Anam
analytical skills graphene is prepared to kill any type viruses .
Anam
Any one who tell me about Preparation and application of Nanomaterial for drug Delivery
Hafiz
what is Nano technology ?
Bob Reply
write examples of Nano molecule?
Bob
The nanotechnology is as new science, to scale nanometric
brayan
nanotechnology is the study, desing, synthesis, manipulation and application of materials and functional systems through control of matter at nanoscale
Damian
Is there any normative that regulates the use of silver nanoparticles?
Damian Reply
what king of growth are you checking .?
Renato
What fields keep nano created devices from performing or assimulating ? Magnetic fields ? Are do they assimilate ?
Stoney Reply
why we need to study biomolecules, molecular biology in nanotechnology?
Adin Reply
?
Kyle
yes I'm doing my masters in nanotechnology, we are being studying all these domains as well..
Adin
why?
Adin
what school?
Kyle
biomolecules are e building blocks of every organics and inorganic materials.
Joe
how did you get the value of 2000N.What calculations are needed to arrive at it
Smarajit Reply
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Source:  OpenStax, Automatic white blood cell classification using svm and neural networks. OpenStax CNX. Dec 16, 2015 Download for free at http://legacy.cnx.org/content/col11924/1.5
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