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What does the amino acid composition analysis show as the most common amino acid in this protein? (Is that unusual?)

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What is the chemical formula for the query protein?

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What is the predicted extinction coefficient at 280 nm, in 6M guanidium HCl, 0.02M phosphate, pH6.5 buffer, assuming all cysteines appear as half cysteines?

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In what way could it be helpful to know the extinction coefficient?

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According to the instability index, is this protein classified as stable or unstable?

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Return again to the ExPASy tools . Notice there are two sections dealing with structure prediction, secondary structure prediction tools and tertiary structureprediction and visualization tools. The secondary structure prediction tools are designed to predict features such as the helical content, the betasheet formations, and the turns, loops, and coil regions within a protein, given the sequence.

Explore the secondary structure tools independently, and submit the diacylglycerol kinase sequenceabove to any of the available secondary structure prediction tools. Most of these tools will email the results, with at leasta 20 minute delay between submission and receipt of results. Forward a results summary to the instructor, outlining the predictions created bythe program of choice.

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Tertiary structure prediction tools match the query sequence with sequences, or partial sequences, of proteins where the 3-Dstructure has been published in the Protein Data Bank (PDB). These tools will produce a model of the query protein by piecing together the structuralregions from the best matches in the PDB, and threading the query sequence through the predicted structure. For more detailed explanations of available3-D structure prediction software, view the Swiss-Model demo page and the Geno3D reference page . Although both of these tools are searching for templates from existing PDB entries, they are doing this in different ways.

What program does Swiss-Model use to match the query sequence with sequences of known structures?

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What program does Geno3D use to match the query sequence with sequences of known structures?

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Notice that the template selection process and the model structure refinement processes are different between these two programs as well.

Finally, in the tertiary structure section of the ExPASy tools page, Swiss PDB Viewer is a graphical tool for the visualization, comparison and analysis of3-D coordinate files. Swiss PDB Viewer can superimpose 3-D structures by finding the rotation and translation that most closely aligns the two proteinstructures. Additionally, the Swiss PDB Viewer will perform amino acid mutations, prediction of hydrogen bonds, and calculation of angles anddistances between atoms. Best of all, Swiss PDB Viewer is freeware and available for many different platforms, including Macintosh, PC, SGI IRIX,and Linux.

View this supplemental SPDBV web page . What other function does Swiss PDB Viewer have, when used in conjunction withother applications such as OpenGL or POV-Ray?

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ExPASy provides a very large library of tools, for proteomics as well as other bioinformatics applications.For those students interested in future research in the field of proteomics,this web server will be an important resource.

Questions & Answers

Application of nanotechnology in medicine
what is variations in raman spectra for nanomaterials
Jyoti Reply
I only see partial conversation and what's the question here!
Crow Reply
what about nanotechnology for water purification
RAW Reply
please someone correct me if I'm wrong but I think one can use nanoparticles, specially silver nanoparticles for water treatment.
Damian
yes that's correct
Professor
I think
Professor
what is the stm
Brian Reply
is there industrial application of fullrenes. What is the method to prepare fullrene on large scale.?
Rafiq
industrial application...? mmm I think on the medical side as drug carrier, but you should go deeper on your research, I may be wrong
Damian
How we are making nano material?
LITNING Reply
what is a peer
LITNING Reply
What is meant by 'nano scale'?
LITNING Reply
What is STMs full form?
LITNING
scanning tunneling microscope
Sahil
how nano science is used for hydrophobicity
Santosh
Do u think that Graphene and Fullrene fiber can be used to make Air Plane body structure the lightest and strongest. Rafiq
Rafiq
what is differents between GO and RGO?
Mahi
what is simplest way to understand the applications of nano robots used to detect the cancer affected cell of human body.? How this robot is carried to required site of body cell.? what will be the carrier material and how can be detected that correct delivery of drug is done Rafiq
Rafiq
if virus is killing to make ARTIFICIAL DNA OF GRAPHENE FOR KILLED THE VIRUS .THIS IS OUR ASSUMPTION
Anam
analytical skills graphene is prepared to kill any type viruses .
Anam
what is Nano technology ?
Bob Reply
write examples of Nano molecule?
Bob
The nanotechnology is as new science, to scale nanometric
brayan
nanotechnology is the study, desing, synthesis, manipulation and application of materials and functional systems through control of matter at nanoscale
Damian
Is there any normative that regulates the use of silver nanoparticles?
Damian Reply
what king of growth are you checking .?
Renato
What fields keep nano created devices from performing or assimulating ? Magnetic fields ? Are do they assimilate ?
Stoney Reply
why we need to study biomolecules, molecular biology in nanotechnology?
Adin Reply
?
Kyle
yes I'm doing my masters in nanotechnology, we are being studying all these domains as well..
Adin
why?
Adin
what school?
Kyle
biomolecules are e building blocks of every organics and inorganic materials.
Joe
anyone know any internet site where one can find nanotechnology papers?
Damian Reply
research.net
kanaga
sciencedirect big data base
Ernesto
Introduction about quantum dots in nanotechnology
Praveena Reply
hi
Loga
what does nano mean?
Anassong Reply
nano basically means 10^(-9). nanometer is a unit to measure length.
Bharti
how did you get the value of 2000N.What calculations are needed to arrive at it
Smarajit Reply
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Source:  OpenStax, Bios 533 bioinformatics. OpenStax CNX. Sep 24, 2008 Download for free at http://cnx.org/content/col10152/1.16
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