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We found earlier that various probability density functions are the limiting distributions of others; thus, we can estimate one with another under certain circumstances. We will find here that the normal distribution can be used to estimate a binomial process. The Poisson was used to estimate the binomial previously, and the binomial was used to estimate the hypergeometric distribution.

In the case of the relationship between the hypergeometric distribution and the binomial, we had to recognize that a binomial process assumes that the probability of a success remains constant from trial to trial: a head on the last flip cannot have an effect on the probability of a head on the next flip. In the hypergeometric distribution this is the essence of the question because the experiment assumes that any "draw" is without replacement. If one draws without replacement, then all subsequent "draws" are conditional probabilities. We found that if the hypergeometric experiment draws only a small percentage of the total objects, then we can ignore the impact on the probability from draw to draw.

Imagine that there are 312 cards in a deck comprised of 6 normal decks. If the experiment called for drawing only 10 cards, less than 5% of the total, than we will accept the binomial estimate of the probability, even though this is actually a hypergeometric distribution because the cards are presumably drawn without replacement.

The Poisson likewise was considered an appropriate estimate of the binomial under certain circumstances. In Chapter 4 we found that if the number of trials of interest is large and the probability of success is small, such that μ = n p < 7 , then Poisson can be used to estimate the binomial with good results. Again, these rules of thumb do not in any way claim that the actual probability is what the estimate determines, only that the difference is in the third or fourth decimal and is thus de minimus .

Here, again, we find that the normal distribution makes particularly accurate estimates of a binomial process under certain circumstances. [link] is a frequency distribution of a binomial process for the experiment of flipping three coins where the random variable is the number of heads. The sample space is listed below the distribution. The experiment assumed that the probability of a success is 0.5; the probability of a failure, a tail, is thus also 0.5. In observing [link] we are struck by the fact that the distribution is symmetrical. The root of this result is that the probabilities of success and failure are the same, 0.5. If the probability of success were smaller than 0.5, the distribution becomes skewed right. Indeed, as the probability of success diminishes, the degree of skewness increases. If the probability of success increases from 0.5, then the skewness increases in the lower tail, resulting in a left-skewed distribution.

The reason the skewness of the binomial distribution is important is because if it is to be estimated with a normal distribution, then we need to recognize that the normal distribution is symmetrical. The closer the underlying binomial distribution is to being symmetrical, the better the estimate that is produced by the normal distribution. [link] shows a symmetrical normal distribution transposed on a graph of a binomial distribution where p = 0.2 and n = 5. The discrepancy between the estimated probability using a normal distribution and the probability of the original binomial distribution is apparent. The criteria for using a normal distribution to estimate a binomial thus addresses this problem by requiring BOTH np AND np (1 − p ) are greater than five. Again, this is a rule of thumb, but is effective and results in acceptable estimates of the binomial probability.

Questions & Answers

how does Neisseria cause meningitis
Nyibol Reply
what is microbiologist
Muhammad Reply
what is errata
Muhammad
is the branch of biology that deals with the study of microorganisms.
Ntefuni Reply
What is microbiology
Mercy Reply
studies of microbes
Louisiaste
when we takee the specimen which lumbar,spin,
Ziyad Reply
How bacteria create energy to survive?
Muhamad Reply
Bacteria doesn't produce energy they are dependent upon their substrate in case of lack of nutrients they are able to make spores which helps them to sustain in harsh environments
_Adnan
But not all bacteria make spores, l mean Eukaryotic cells have Mitochondria which acts as powerhouse for them, since bacteria don't have it, what is the substitution for it?
Muhamad
they make spores
Louisiaste
what is sporadic nd endemic, epidemic
Aminu Reply
the significance of food webs for disease transmission
Abreham
food webs brings about an infection as an individual depends on number of diseased foods or carriers dully.
Mark
explain assimilatory nitrate reduction
Esinniobiwa Reply
Assimilatory nitrate reduction is a process that occurs in some microorganisms, such as bacteria and archaea, in which nitrate (NO3-) is reduced to nitrite (NO2-), and then further reduced to ammonia (NH3).
Elkana
This process is called assimilatory nitrate reduction because the nitrogen that is produced is incorporated in the cells of microorganisms where it can be used in the synthesis of amino acids and other nitrogen products
Elkana
Examples of thermophilic organisms
Shu Reply
Give Examples of thermophilic organisms
Shu
advantages of normal Flora to the host
Micheal Reply
Prevent foreign microbes to the host
Abubakar
they provide healthier benefits to their hosts
ayesha
They are friends to host only when Host immune system is strong and become enemies when the host immune system is weakened . very bad relationship!
Mark
what is cell
faisal Reply
cell is the smallest unit of life
Fauziya
cell is the smallest unit of life
Akanni
ok
Innocent
cell is the structural and functional unit of life
Hasan
is the fundamental units of Life
Musa
what are emergency diseases
Micheal Reply
There are nothing like emergency disease but there are some common medical emergency which can occur simultaneously like Bleeding,heart attack,Breathing difficulties,severe pain heart stock.Hope you will get my point .Have a nice day ❣️
_Adnan
define infection ,prevention and control
Innocent
I think infection prevention and control is the avoidance of all things we do that gives out break of infections and promotion of health practices that promote life
Lubega
Heyy Lubega hussein where are u from?
_Adnan
en français
Adama
which site have a normal flora
ESTHER Reply
Many sites of the body have it Skin Nasal cavity Oral cavity Gastro intestinal tract
Safaa
skin
Asiina
skin,Oral,Nasal,GIt
Sadik
How can Commensal can Bacteria change into pathogen?
Sadik
How can Commensal Bacteria change into pathogen?
Sadik
all
Tesfaye
by fussion
Asiina
what are the advantages of normal Flora to the host
Micheal
what are the ways of control and prevention of nosocomial infection in the hospital
Micheal
what is inflammation
Shelly Reply
part of a tissue or an organ being wounded or bruised.
Wilfred
what term is used to name and classify microorganisms?
Micheal Reply
Binomial nomenclature
adeolu
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Source:  OpenStax, Introductory statistics. OpenStax CNX. Aug 09, 2016 Download for free at http://legacy.cnx.org/content/col11776/1.26
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