<< Chapter < Page Chapter >> Page >
This module is an introduction to performing searches of the NCBI databases using Entrez, the NCBI web-based search and retrieval tool for integrated search results from multiple databases.

Entrez (1) is a search and retrieval tool developed by NCBI that is capable of searching multiple NCBI databases with just one query. Entrez returns search results that can include a combination of many types of data on the query, such as nucleotide sequences, protein sequences, macromolecular structures, and related articles in the literature. Prior to the creation of Entrez, an individual might have to place one query to a nucleotide database to find a nucleotide sequence, submit another query to a structural database to find the published structure of the gene product, and submit a final query to a literature database to find citations for journal articles on the query topic. NCBI recognized the time and effort that could be saved by a tool that could cross-link these databases and integrate all information related to a given query subject into one report.View the Entrez Database page . This module contains a few problem questions, for use in a computer lab setting. The lab instructor may require that yousupply answers to these questions as an indication that you have completed the module.

The Entrez Nucleotides database includes sequences from GenBank, RefSeq, and PDB. GenBank is the National Institutes of Health (NIH) genetic sequencedatabase. GenBank, the DNA DataBank of Japan (DDBJ) and the European Molecular Biology Laboratory (EMBL) comprise the International Nucleotide SequenceDatabase Collaboration. These three organizations exchange data on a daily basis. The number of bases in the Entrez Nucleotides database currently growsat an exponential rate. Click on the Nucleotide link listed under the heading "Nucleotide Databases".

What is the number of bases stored in the Entrez nucleotide database, as of the last report?

Got questions? Get instant answers now!

Use the back arrow of the browser to return to the Entrez Database web page. Locate the MMDB (Molecular Modeling DataBase), one of NCBI's structure databases and clickon the link to read about it. MMDB is a subset of three-dimensional structures obtained from the ProteinData Bank (PDB), excluding theoretical models. While the protein databases contain protein sequences, the structural database contains coordinate files (PDB files) of biological molecules with solved (known) structures.Click on the arrow next to the search box at the top of the web page and view the list of databases for selection.The literature database is accessed through PubMed, which encompasses the National Library of Medicine'sjournals database, MEDLINE, as well as providing some additional online services. MEDLINE is a collection of medical and life science journalcitations that includes articles dating back to the mid-1960's.Entrez allows access to information such as nucleotide and protein sequencesorganized by species in the NCBI taxonomy database, also found on the selection list. The connectivity of the databases available on the selection list are indicated by the diagram on the Entrez Database web page . Click on the diagram to access a Flash model of Entrez database connectivity. As long as the browser has a Flash plug-in, placing the mouse over one of the nodes representing a database will highlight its connectivity.Try this on the node labeled "Protein". Actually clicking on the node will forward the user to the database home page.

Questions & Answers

how environment affect demand and supply of commodity ?
Amos Reply
Wht at the criteria for market ?
Amos
what is difference between monitory policy and fiscal policy?
Malik Reply
monetary policy is a policy thrust by National Govt(CBN) to influence government spending, purchase &taxes
Frank
necessity of economics
Pamela Reply
I will say want,choice,opportunity cost,scarcity,scale of preference
Alao
what is monopoly market.How price output are determined under monopoly market
bisham
b) Monopoly market is an impecfect market where s single firm having the innovation to produce a particular commodity.Prices are determined through output since there are no other competitive.
Frank
Monopoly market:firm has market power & does not respond to market price
Frank
Explain the process of price determination under perfect competition market with suitable diagram
bisham Reply
Price determination under perfect competition via this process :firms have no market power to influence price rather firms respond to market price.
Frank
price is different from demand- demand is amount of commodity
Effah Reply
demand is amount /quantity of commodity a potential buyer is willing to buy at a given price at market
Frank
demand is a desire of customer on commodity with the ability to pay it and willing to buy it at given price of commodity
Harika
demand is price of what
Faith Reply
show that shortrun average cost
Baby Reply
what is economics
Mbah Reply
what is money
Mbah
what is money
Mbah
Difine macro economics
agaba
money is a medium of exchange between goods and services,maybe inform of currency.
Wesonga
Economics is study of how human beings strive to satisfy numerous wants using limited available resources.
Wesonga
how do you find the maximum number of workers the firms should employ order to produce where there are increasing returns
Jane
what are implications of computing national income?.
agaba
pl
MUDASIRU
what is the formulae for calculating national income
MUDASIRU
it calculated by value added method
Praveen
classify the production units like agriculture, banking, transport etc
Praveen
money is anything that is generally acceptetable for human
Ogbaji
Estimate the net value added(NVA) at fixed cost by each industrial structure
Praveen
definition of unemployment
Adam Reply
what are the causes of unemployment?
Mbubi Reply
The main causes of unemployment are listed below. 1. Frictional unemployment 2. Cyclical unemployment 3. Structural unemployment
assani
We can also categorize the causes on a broader sense as: 1. Political and 2. Social cause As unemployeement root causes are embaded in this two.
Yonathan
would opportunity cost exist if there was no scarcity?
assani
yes just because the opportunity cost arose when there is Alternative to choose among the alternatives.
BADAMASIU
I am thinking that, if our resources were unlimited, then there wouldn't be any need to forgo some wants. Hence the inexistence if opportunity cost
assani
Politics
Job
politics has done what?
assani
consider time assani
Mary
I'm Emmanuel,...I taught the main cause is the change in gov't.
Emmanuel
...Lack of capital to set up a firm respectively
Emmanuel
🙈
Emmanuel
I would like to bring in Educational levels can also be the cause the cause of the problem respectively
Emmanuel
I think the main causes of unemployment is lack of INFRASTRUCTURAL DEVELOPMENT OVER POPULATION OVER DEPENDENT ON GOVERNMENT LACK OF SELF EMPOWERMENT...
ananti
lack of skills among the new generation is the serious issue.
Vishal
Where I come from , I don't see why education or personal aspects seem to do with unimployment, technically the motivation and eigerness in all works of live is there , dispite the cultural influence and physical bearriors;the thing we lacking is Government Support and open market ethics.
Joe
sorry about that-(repation). We have a over powering ethical political system that's displacing the marketing asspects of economy and causing large scale unemployment right across the board...
Joe
can someone Explain Expansionary Monetary Policy and Contractionary Monetary Policy Using one of the instrument of Monetary Policy? Please am kinda lost here?. ta
Emmanuel Reply
using a graph show the case of substitute and compliment goods
Ade Reply
can anyone give me a simple explanation to Five Sector Macroeconomics?
Emmanuel
Can someone please define what economics is
jason Reply
economics simply is a social science subject that study human behavior.
dajan
economics is a social science which studies human behaviour as a relationship between ends and scarce means that has alternative uses
Alao
Can someone please tell me how to calculate GDP
Emmanuel
emmanual kapal to calculate GDP (Gross Domestic Product) has three method in calculating it (1)income approach (2) expenditure approach (3) value added method
Alao
thanks Alae
Emmanuel
u are welcome
Alao
in basic terms economics is revered to as battery system, it date back to when Men sees the need to exchange sapless goods and produce to gain , either wealth , basic necessities or to establish trading ties for personal benefit or social asspects in terms of coexistence and continuity, future .
Joe
what is the law of demand
Berlinda Reply
keep other thing constant, when the price increases demand decrease when the price decreases demand increases of the commodity.
sj
all things being equal,quantity demanded decrease as price increase and increase as price decrease
Seth
there's practial joke to it ..." the higher the demand ; scarcity, increase in production and drop in quality"... quite the controversy - for example China vs Europe, United States and we are all boxed up in between somewhere...
Joe
Other thing remain constant the low price of commodity the high quantity of commodity and vice versa is true
Baraka
Explain Effective demand
Anita Reply
What is effective demand
Anita
like Modi is in demand...best example of effective demand
Pranav
Don't get you
Anita
Anita you mean you don't get me or who?
Onyeking
level of demand that represents a real intention to purchase by people with the means to pay
Pranav
Got questions? Join the online conversation and get instant answers!
Jobilize.com Reply

Get the best Algebra and trigonometry course in your pocket!





Source:  OpenStax, Bios 533 bioinformatics. OpenStax CNX. Sep 24, 2008 Download for free at http://cnx.org/content/col10152/1.16
Google Play and the Google Play logo are trademarks of Google Inc.

Notification Switch

Would you like to follow the 'Bios 533 bioinformatics' conversation and receive update notifications?

Ask