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10. Repeat the above procedure with a new sample of the same antacid. Enter your data in a wiki in the designated laptop, check the web page later on the week and make a final comment on the overall cost to neutralize one mole of HCl for various brands. Use the data from your lab section (i.e. all of Tuesday afternoon, Monday night, etc.).THIS IS PART OF YOUR REPORT AND IF DATA IS NOT FOUND ON THE WEB YOU SHOULD CONTACT YOUR TA. (No excuses)

Retail cost maximum

  Label Antacid Brand Price (cents per tablet) Fraction
B Walgreens Antacid Tablets 2.66 1/6
C Titralac Plus 5.99 1/4
E Rolaids 2.69 1/4
J Tums Regular 2.86 1/6
K Tums Plus 5.32 1/6
M Eckerd Antacid 2.19 1/6

 *Active ingredient in all of these antacids is CaCO 3 size 12{ ital "CaCO" rSub { size 8{3} } } {} .

Supporting information on standardization:

Molarity is the most commonly used concentration term when one is interested in the amount of materials involved in a chemical reaction in solution. Molarity (M) is defined as the number of moles of solute per liter of solution.

M = moles ( solute ) Liters ( solution ) size 12{ { {# ital "moles" \( ital "solute" \) } over { ital "Liters" \( ital "solution" \) } } } {} (1)

The number of moles is calculated by dividing the mass of the sample in grams by the gram formula weight (GFW or molar mass). One GFW is the same as one mole.

Number moles = grams ( solute ) GFW size 12{ { { ital "grams" \( ital "solute" \) } over { ital "GFW"} } } {} (2)

For example in a 0.150 M HNO 3 size 12{ ital "HNO" rSub { size 8{3} } } {} solution, there are 0.150 moles of HNO 3 size 12{ ital "HNO" rSub { size 8{3} } } {} in one liter of this solution. The following factors may then be used in chemical calculations: 

0 . 150 molHNO 3 1L ( solution ) size 12{ { {0 "." "150" ital "molHNO" rSub { size 8{3} } } over {1L \( ital "solution" \) } } } {} or 1L ( solution ) 0 . 150 molHNO 3 size 12{ { {1L \( ital "solution" \) } over {0 "." "150" ital "molHNO" rSub { size 8{3} } } } } {}

In a chemical reaction that takes place in solution, the volume and the molarity of one reactant and the molarity of the second reactant can be used, together with the stoichiometry of the equation, to find the volume of the second reactant needed to react completely with the first reactant.

Titration is a process in which a solution of one reagent, usually the base, is added to an accurately measured volume of another solution, usually the acid, until the reaction is complete. The concentration of one of the reagents is known. From the known concentration and the measured volumes, the concentration of the second solution can be calculated.

In acid-base reactions the end of the reaction or equivalence point is detected by adding a compound that undergoes a color change as it changes from its acid form to its basic form. This compound is called an indicator. An indicator is an organic dye that changes color at a characteristic H + size 12{H rSup { size 8{+{}} } } {} ion concentration. A dye can be an indicator if it has an intense color that changes when it gains or loses H + size 12{H rSup { size 8{+{}} } } {} ions.

HIn + OH In + H 2 O size 12{ ital "HIn"+ ital "OH" rSup { size 8{ - {}} } rightarrow ital "In" rSup { size 8{ - {}} } +H rSub { size 8{2} } O} {} (3)

The change of an indicator dye from Color A to Color B depends upon the concentration of H + size 12{H rSup { size 8{+{}} } } {} (or OH size 12{ ital "OH" rSup { size 8{ - {}} } } {} ) ions. Care must be taken in selecting an indicator to be sure that the color change (endpoint) occurs at the H + size 12{H rSup { size 8{+{}} } } {} ion concentration that corresponds to the equivalence point. Phenolphthalein, methyl red, methyl orange, and litmus are examples of indicators.

A primary standard is usually a solid reactant that:

(1) is available in a high purity form

(2) does not change chemically when stored or exposed to air

(3) has a high formula weight to minimize errors in weighing

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Source:  OpenStax, General chemistry lab spring. OpenStax CNX. Apr 03, 2009 Download for free at http://cnx.org/content/col10506/1.56
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