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Final exam for all Carbohydrate and Nitrogen lectures.
1. Which of the following molecules CANNOT be excreted by the kidneys as glucuronides?
A. Bile (stercobilin)
B. Progesterone
C. Bilirubin diglucuronide
D. Morphine
E. Thyroid hormone
2. Which of the following molecules DOES NOT accumulate in blood as a result of a defect in any of the enzymes of the urea cycle?
A. Any of the intermediates of the urea cycle
B. Ammonia in the form of NH4+
C. Glutamine and alanine
D. All the intermediates of glycolysis
3. Which of the following hormones regulates the excretion of both water and sodium counteracting the effects of other water homeostasis hormones?
A. Aldosterone
B. Antidiuretic hormone
C. Cortisol
D. Estrogen
E. Natriuretic peptides
4. Which of the following digestive enzymes pairs can break peptide bonds at either terminal end of a polypeptide?
A. Trypsin&chymotrypsin
B. Elastase&collagenase
C. Aminopeptidase and carboxypeptidase
D. Dipeptidase&tripeptidase
E. Enterokinase and Phospholipase A
5. Which of the following enzymes pairs can perform autocatalysis once they are activated?
A. Pepsin&trypsin
B. Aminopeptidase&carboxypeptidase
C. Elastase&collagenase
D. Dipeptidase&tripeptidase
E. Chymotrypsin&Phospholipase A
6. Which of the following zymogens can help in the screening of gastric disorders?
A. Trypsinogen
B. Pepsinogen
C. Chymotrypsinogen
D. Procollagenase
E. Procarboxypeptidase
7. Which of the following disorders can affect the release of pancreatic digestive enzymes into the intestinal lumen?
A. Hartnup disease
B. Cystinuria
C. Cystic fibrosis
D. Atrophic gastritis
E. Duodenal ulcer
8. Which of the following mechanisms facilitates the absorption and release of hydrophobic amino acids into the body's cells?
A. Aquaporins
B. Autophagosomes
C. Secondary active transporters
D. Simple diffusion
E. Facilitated diffusion
9. Which of the following statements about the degradation of body's proteins is INCORRECT ?
A. Proteins for degradation are recognized based on the presence of ubiquiting tags, PEST sequences, N-terminal or oxidized residues.
B. A single ubiquitin isopeptide assigns a regulatory function to a protein but multiple ubiquitin isopeptides targets the protein for degradation.
C. E1 binds and transfer an ubiqutin molecule to E2 and E3 joins the ubiquitin from E2 to the end terminal end of a target protein.
D. Lysosomal proteases break down body' proteins into polypeptides; while, proteasome complexes break them into single amino acids.
E. Binding of N-acetylglucosamine to the active sites of the proteasome inhibits protein degradation and the removal of this molecule facilitates protein degradation.
10. Which of the following digestive enzymes pairs can break peptide bonds at either terminal end of a polypeptide?
A. Trypsin&chymotrypsin
B. Elastase&collagenase
C. Aminopeptidase and carboxypeptidase
D. Dipeptidase&tripeptidase
E. Enterokinase and Phospholipase A
11. Which of the following enzymes pairs need to be activated via autocatalysis?
A. Pepsin&lysosomal proteases
B. Aminopeptidase&carboxypeptidase
C. Elastase&collagenase
D. Dipeptidase&tripeptidase
E. Chymotrypsin&Phospholipase A

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Source:  OpenStax, Biochemistry exercises. OpenStax CNX. Apr 06, 2016 Download for free at https://legacy.cnx.org/content/col11386/1.4
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