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This is the heart of a 38-year-old, previously healthy, asymptomatic woman who suddenly collapsed and died while watchingTV.

147. metastatic melanoma

Autopsy of this patient disclosed extensive metastases not only to her heart, but also to her liver and intestines (imagebelow). The site of the primary melanoma was never established. Death undoubtedly resulted from an arrhythmia.

Cardiac metastases ordinarily are clinically silent. But when signs or symptoms do occur, pericardial effusion (with orwithout tamponade) and dysrhythmias are the most common presentations. Cardiac failure, however, as well as superior vena caval syndrome and othermanifestations related to intracavitary metastases, may develop as well.

From a percentage standpoint, melanoma is the most frequent neoplasm metastasizing to the heart (about 65%). Furthermore, theabsolute amount of tumor deposited in the heart in cases of melanoma is far greater than that of any other cancer. In one reported case, for example, themelanoma-infiltrated heart weighed 2450 gm! Findings of this sort have given rise to the term “charcoal heart.”

Questions & Answers

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the study of living organisms and their interactions with one another and their environments
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HOW CAN MAN ORGAN FUNCTION
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the diagram of the digestive system
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They formed in two ways first when one sperm and one egg are splited by mitosis or two sperm and two eggs join together
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Genetics is the study of heredity
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the study of living organisms and their interactions with one another and their environment.
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list any five characteristics of the blood cells
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advantage of electronic microscope is easily and clearly while disadvantage is dangerous because its electronic. advantage of light microscope is savely and naturally by sun while disadvantage is not easily,means its not sharp and not clear
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is organisms that are similar into groups called tara
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A scanning electron microscope (SEM) is ideal for situations requiring high-resolution imaging of surfaces. It is commonly used in materials science, biology, and geology to examine the topography and composition of samples at a nanoscale level. SEM is particularly useful for studying fine details,
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Source:  OpenStax, Images of memorable cases: 50 years at the bedside. OpenStax CNX. Dec 08, 2008 Download for free at http://cnx.org/content/col10449/1.7
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