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Information Flow and Genetics

  1. Genetic variations can impact microbial functions (e.g., in biofilm formation, pathogenicity and drug resistance).
  2. Although the central dogma is universal in all cells, the processes of replication, transcription, and translation differ in Bacteria, Archaea, and Eukaryotes.
  3. The regulation of gene expression is influenced by external and internal molecular cues and/or signals.
  4. The synthesis of viral genetic material and proteins is dependent on host cells.
  5. Cell genomes can be manipulated to alter cell function.

Microbial Systems

  1. Microorganisms are ubiquitous and live in diverse and dynamic ecosystems.
  2. Most bacteria in nature live in biofilm communities.
  3. Microorganisms and their environment interact with and modify each other.
  4. Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.

Impact of Microorganisms

  1. Microbes are essential for life as we know it and the processes that support life (e.g., in biogeochemical cycles and plant and/or animal microbiota).
  2. Microorganisms provide essential models that give us fundamental knowledge about life processes.
  3. Humans utilize and harness microorganisms and their products.
  4. Because the true diversity of microbial life is largely unknown, its effects and potential benefits have not been fully explored.

PART 2: Competencies and Skills

Scientific Thinking

  1. Ability to apply the process of science
    a. Demonstrate an ability to formulate hypotheses and design experiments based on the scientific method.
    b. Analyze and interpret results from a variety of microbiological methods and apply these methods to analogous situations.
  2. Ability to use quantitative reasoning
    a. Use mathematical reasoning and graphing skills to solve problems in microbiology.
  3. Ability to communicate and collaborate with other disciplines
    a. Effectively communicate fundamental concepts of microbiology in written and oral format.
    b. Identify credible scientific sources and interpret and evaluate the information therein.
  4. Ability to understand the relationship between science and society
    a. Identify and discuss ethical issues in microbiology.

Microbiology Laboratory Skills

  1. Properly prepare and view specimens for examination using microscopy (bright field and, if possible, phase contrast).
  2. Use pure culture and selective techniques to enrich for and isolate microorganisms.
  3. Use appropriate methods to identify microorganisms (media-based, molecular and serological).
  4. Estimate the number of microorganisms in a sample (using, for example, direct count, viable plate count, and spectrophotometric methods).
  5. Use appropriate microbiological and molecular lab equipment and methods.
  6. Practice safe microbiology, using appropriate protective and emergency procedures.
  7. Document and report on experimental protocols, results and conclusions.

Openstax Microbiology Correlation to asm recommended curriculum guidelines for undergraduate microbiology education

OpenStax Microbiology Correlation to ASM Curriculum Guidelines
Chapter ASM Curriculum Guidelines
1—An Invisible World 2, 4, 5, 11, 16, 20, 23, 26, 27, 31
2—How We See the Invisible World 6, 31, 32, 33
3—The Cell 1, 2, 5, 9, 16, 21, 25, 31
4—Prokaryotic Diversity 2, 4, 8, 11, 12, 16, 20, 23, 24, 31
5—The Eukaryotes of Microbiology 2, 4, 5, 9, 12, 20, 23, 31
6—Acellular Pathogens 4, 10, 18, 23, 31
7—Microbial Biochemistry 1, 24, 33, 34
8—Microbial Metabolism 1, 11, 12, 13, 22, 24
9—Microbial Growth 12, 13, 29, 31, 33, 34, 35
10—Biochemistry of the Genome 1, 16, 25, 31
11—Mechanisms of Microbial Genetics 1, 2, 15, 16, 17, 31
12—Modern Applications of Microbial Genetics 19, 26, 31
13—Control of Microbial Growth 13, 14, 26, 31, 36, 37
14—Antimicrobial Drugs 3, 7, 14, 15, 23, 26, 31
15—Microbial Mechanisms of Pathogenicity 8, 9, 10, 15, 18, 23, 33
16—Disease and Epidemiology 7, 14, 23, 26, 31
17—Innate Nonspecific Host Defenses 7, 8, 23
18—Adaptive Specific Host Defenses 7, 23, 26, 31
19—Diseases of the Immune System 7, 8, 24
20—Laboratory Analysis of the Immune Response 31, 34
21—Skin and Eye Infections 8, 9, 10, 14, 18, 23, 24, 31
22—Respiratory System Infections 7, 8, 9, 14, 18, 23, 24, 31
23—Urogenital System Infections 7, 8, 9, 12, 14, 18, 22, 23, 24, 31
24—Digestive System Infections 7, 8, 9, 10, 14, 18, 23, 24, 31
25—Circulatory and Lymphatic System Infections 7, 8, 9, 14, 23, 31
26—Nervous System Infections 7, 8, 9, 14, 18, 23, 24, 31

Questions & Answers

characteristic of Gram negative bacteria
jane Reply
Characteristics of Gram Negative Bacteria As with Gram positive bacteria, Gram negative bacteria also contain the peptidoglycan polymer in their cell wall. While this polymer is thin (2 to 4 nanometers in thickness with just about 3 layers of peptidoglycan) in Gram negative bacteria, it's also com
Kaviya
it's also composed of long glycan strands that are cross-linked by peptide molecules. This composition serves a number of functions including protecting the bacterial cell from lysis
Kaviya
Good shot
Enoch
Thanks 😊
Kaviya
what was Hans Christian Gram's supported in the modern Microbiology?
Wilson Reply
what is microbial growth
Chisa Reply
The organism responsible for vulva ulcers
nyiter Reply
Why are vascular pathogen poorly communicable from person to person?
Aj Reply
Most vascular pathogens are poorly communicable from person to person because they need a medium to be communicated i,e a vector that would carry them from one person to other
Kaviya
what's the habit of protista
Afieahngwi Reply
They show both autotrophic and heterotrophic mechanisms...
Swetha
thanks
Afieahngwi
welcome...
Swetha
let me mention some water. Air .Food and so on
Gattiek Reply
causes of infectious diseases
Afieahngwi Reply
water.Air
Gattiek
infectious disease are caused by pathogenic micro organisms like bacteria ,fungi..
Swetha
What is pasteurization?
Wilson
are fungi prokaryote or eukaryotes?
Afieahngwi Reply
fungi are eukaryotes.
Swetha
All fungi are eukaryotes. Even micro fungi.
Lad
have..complex cellular organization and membrane bound nucleus ...and..also... having loops of DNA( like plasmids) as.bacteria
Swetha
what enzyme replaces rna nucleotides with dna nucleotides during replication?
Remi Reply
an enzyme called DNA ligase.
Jael
describe the acid fast staining procedure used in the diagnosis of tuberculosis
Salma Reply
bacterial morphology
lf_ Reply
what is the difference between biogenesis & abiogenesis
Mayuri Reply
biogenesis is when living comes out from other living things as a result of reproduction while a biogenesis is the process where living things comes out from non living things
Usman
living things come form other form living things is biogenesis. ....right?
Mayuri
what is mean by pasturation method?
Mayuri Reply
Pasteurization is a process that kills harmful bacteria and creates an extended shelf life for your milk. ... It's pretty simple—we take the milk from the cows, we rapidly heat it to a high enough temperature to kill the bacteria, and then we cool it back down before packaging and shipping it to you
Kaviya
tell me about abiogenessis &biogenesis
Mayuri
discribe aristol spontaneous generation theory in brif
Mayuri Reply
The Greek philosopher Aristotle (384–322 BC) was one of the earliest recorded scholars to articulate the theory of spontaneous generation, the notion that life can arise from nonliving matter. Aristotle proposed that life arose from nonliving material if the material contained pneuma (“vital heat”).
Kaviya
thank you 😊
Mayuri
No mention dear 😊
Kaviya

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Source:  OpenStax, Microbiology. OpenStax CNX. Nov 01, 2016 Download for free at http://cnx.org/content/col12087/1.4
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