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Pre-embryonic cleavages

This figure shows the different stages of cell divisions taking place before the embryo is formed. The top panel shows the cell divisions occurring in the uterine tube and the bottom panel shows the cell divisions occurring in the uterus.
Pre-embryonic cleavages make use of the abundant cytoplasm of the conceptus as the cells rapidly divide without changing the total volume.

As the blastocyst forms, the trophoblast excretes enzymes that begin to degrade the zona pellucida. In a process called “hatching,” the conceptus breaks free of the zona pellucida in preparation for implantation.

View this time-lapse movie of a conceptus starting at day 3. What is the first structure you see? At what point in the movie does the blastocoel first appear? What event occurs at the end of the movie?

Implantation

At the end of the first week, the blastocyst comes in contact with the uterine wall and adheres to it, embedding itself in the uterine lining via the trophoblast cells. Thus begins the process of implantation    , which signals the end of the pre-embryonic stage of development ( [link] ). Implantation can be accompanied by minor bleeding. The blastocyst typically implants in the fundus of the uterus or on the posterior wall. However, if the endometrium is not fully developed and ready to receive the blastocyst, the blastocyst will detach and find a better spot. A significant percentage (50–75 percent) of blastocysts fail to implant; when this occurs, the blastocyst is shed with the endometrium during menses. The high rate of implantation failure is one reason why pregnancy typically requires several ovulation cycles to achieve.

Pre-embryonic development

This figure shows the different stages in pre-embryonic development. A diagram of the uterus is shown and from this image, eight callouts show the different stages of development.
Ovulation, fertilization, pre-embryonic development, and implantation occur at specific locations within the female reproductive system in a time span of approximately 1 week.

When implantation succeeds and the blastocyst adheres to the endometrium, the superficial cells of the trophoblast fuse with each other, forming the syncytiotrophoblast    , a multinucleated body that digests endometrial cells to firmly secure the blastocyst to the uterine wall. In response, the uterine mucosa rebuilds itself and envelops the blastocyst ( [link] ). The trophoblast secretes human chorionic gonadotropin (hCG)    , a hormone that directs the corpus luteum to survive, enlarge, and continue producing progesterone and estrogen to suppress menses. These functions of hCG are necessary for creating an environment suitable for the developing embryo. As a result of this increased production, hCG accumulates in the maternal bloodstream and is excreted in the urine. Implantation is complete by the middle of the second week. Just a few days after implantation, the trophoblast has secreted enough hCG for an at-home urine pregnancy test to give a positive result.

Implantation

This figure shows the different steps during implantation. The top panel shows how the blastocyst burrows into the endometrium. The middle panel shows the blastocyst completely surrounded by the endometrium. The bottom panel shows the implanted embryo growing in the uterus.
During implantation, the trophoblast cells of the blastocyst adhere to the endometrium and digest endometrial cells until it is attached securely.

Most of the time an embryo implants within the body of the uterus in a location that can support growth and development. However, in one to two percent of cases, the embryo implants either outside the uterus (an ectopic pregnancy    ) or in a region of uterus that can create complications for the pregnancy. If the embryo implants in the inferior portion of the uterus, the placenta can potentially grow over the opening of the cervix, a condition call placenta previa    .

Questions & Answers

What is a dorsal cavity?
John Reply
Explain in detail mitosis and meiosis
sedeck Reply
What is Sodium Potassium Pump?
Mwamba Reply
The process of moving sodium and potassium ions across the cell membrance is an active transport process involving the hydrolysis of ATP to provide the necessary energy. It involves an enzyme referred to as Na+/K+-ATPase
USAMA
yes men.
Carlos
does it mean that there are two definitions of gross anatomy
Esther Reply
what is anatomy?
Hridy Reply
I think it's the study of the internal and external features of the body and its physical relationship between body parts
Esther
anatomy is the study of all the structure of body parts of living organisms
Kishan
jaundice causes by when bilirubin blockage of bilary system
mahamed Reply
Yeah, when there is a blockage in the bilary system( bile ducts) which lead to obstruction of the bile pigments called bilirubin leading to a characteristically yellowish appearance of the eyes.
ibrahim
yes
mahamed
there are three main resons why bilirubin levels in the blood may rise: 1. pre-hepatic jaundice,2. hepatic jaundice, 3. post hepatic
mahamed
hi pls what causes jaundice
Umar Reply
where the love feelings emotions and hate lies in the body?
Loving Reply
what is Regional anatomy
Sharon Reply
Please information on dialysis
Agbo Reply
what is the relationship between Clinical officer general, unqualified professionals and traditional healers?
Purity Reply
is that how the microscopic anatomy is
Elizabeth Reply
to understand the structures of the body. to understand how the structures of the body work . To understand how the structures of the body work and support the functions of life.
Dora Reply
procedures that removes waste from body when kidneys dont function properly..
maribel Reply
Want to join
Ordeal
dialysis
kimunya
dialysis is a process to remove extra fluid , impurities and waste product from the blood and to correct electrolytes imbalance such as sodium, potassium and calcium with the help of dialysis machine. when the kidneys can't do their job.
Kishan
what will lead a person to dialysis
Agbo
what's metabolic acidosis
Nana
A condition in which too much acid accumulates in the body. Causes of metabolic acidosis can include buildup of body toxins, kidney failure, and ingestion of certain drugs or toxins, such as methanol or large doses of aspirin. It can be a rare complication of diabetes.
Loving
What is dialisis
Friday Reply
When kidney is not functioning properly than with the help of dialysis blood filtration is occur Or we can say that it is a process through which filtration of blood is done
sonugora
dialysis is a process of removing wastes, excess fluid ,impurities from the blood and to correct electrolytes imbalance such as sodium, potassium and calcium etc with the help of dialysis machine.when the kidney can't do their job.
Kishan

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Source:  OpenStax, Anatomy & Physiology. OpenStax CNX. Feb 04, 2016 Download for free at http://legacy.cnx.org/content/col11496/1.8
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