Postdoctoral Fellow - Immunology autoimmunity and inflammation

JOB ID: R-183049 LOCATION: US - California - South San Francisco WORK LOCATION TYPE: On Site DATE POSTED: Feb. 21, 2024 CATEGORY: Scientific SALARY RANGE: 76,773.00 USD - 87,171.00 USD

HOW MIGHT YOU DEFY IMAGINATION?

You've worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission-to serve patients-drives all that we do. It is key to our becoming one of the world's leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.

Postdoctoral Fellow - Immunology (autoimmunity and inflammation)

Live

What you will do

Let's do this. Let's change the world. The Post Doctoral Fellow at Amgen conducts research under the supervision of a mentor. They contribute to the design and execution of research projects, the analysis of data, and the preparation of scientific manuscripts.

This is a unique opportunity to be part of Amgen's R&D Postdoc Program in Inflammation Discovery Research, located at a research site in South San Francisco, California. Postdocs will join a biology-centric lab to train under Dr. Zhifei Shao, Principal Scientist, and Dr. Menno Van Lookeren Campagne, VP of Inflammation Research, amongst other leading scientists in the field of immunology. In this vital role, you will perform independent research projects on the molecular and cellular mechanism of a key pathway regulating the homeostasis of the immune response as a part of a highly motivated group of immunologists and critical thinkers dedicated to pushing the boundaries of drug discovery.

The positions are for 2-4 years, depending on the time it takes to complete projects. Successful candidates will have access to Amgen's cutting-edge technologies and innovation and be expected to make exciting scientific contributions to the field, present at scientific conferences, and publish their work. Postdocs will be a part of the broader R&D Postdoc Program that focuses on training the next generation of industry scientists. An overwhelming majority of our postdocs go on to advance their careers in industry at leading pharma and biotech companies, including many at Amgen.

We are looking for highly talented, self-motivated individuals passionate about science and making high-impact discoveries to work on immunology and inflammation research. A major focus will be on a key pathway regulating immune homeostasis in T cells and myeloid cells. New postdoctoral fellows will take a multi-disciplinary approach combining animal disease models, cell biology, chemical and molecular biology, and biochemistry to carry out these studies.

Please see representative publications from Dr. Zhifei Shao and Dr. Menno Van Lookeren Campagne:

• Sci. Immunol. 2021 May 7;6(59):eabe8856

• PNAS. 2020 118 (3) e201#.

• Cell Rep. 2020 Jan 28;30(4):1246-1259.e6

• Nature 2014 506 (2014), 456-62

• J Thromb Haemost. 2015 Jun;13(6):1090-102

• J Bio Chem 2014 Sep 26;289(39):27146-27158

• J Exp Med 2010 Jan 18;207(1):7-16

• J Allergy Clin Immunol 2009 Jun;13(6):1090-102

• Cell 2006 Mar 10;124(5):915-27

• Nature 444, 217-220 (2006)

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dedicated individual we seek is a scientist with these qualifications.

Basic Qualifications:

• Ph. D. at the time of appointment

Preferred Qualifications:

• PhD in immunology, molecular biology, or cell biology with prior research experience in lymphocyte or myeloid cell biology.

• Record of independent critical thinking and the ability to design, execute, and interpret experiments, as exemplified by high-quality publications

• Expertise with mouse handling, in vivo rodent models, multi-color flow cytometry, isolation and culture of primary human and mouse cells and cell lines, cell engineering, scRNA-seq, and/or bioinformatics analysis is also preferred

• Broad knowledge and technical competency of molecular and cellular biology; good understanding of enzymology and protein chemistry

• Excellent organizational, interpersonal and communication skills

• A passion to explore the unknown and make discoveries that will chart new areas of biology

Thrive

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates' professional and personal growth and well-being.

Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

• Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.

• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

• Award-winning time-off plans and bi-annual company-wide shutdowns

• Flexible work models, including remote work arrangements, where possible

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for a career that defies imagination

Objects in your future are closer than they appear. Join us.

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Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

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