• Card 3 / 60: Following the interaction of rhodopsin with light, which of the following play a rolein stopping the downstream signaling? (3 points)
    A) The G-protein coupled receptor transducin is hydrolyzes its GTP and ceases to signal.
    B) Active rhodopsin eventually hydrolyses its GTP and ceases to signal.
    C) Active transducin is phosphorylated by opsin kinase and then inactived by arrestin.
    D) Active rhodopsin is phosphorylated by opsin kinase and then inactived by arrestin.
    E) Active rhodopsin is phosphorylated by opsin kinase and then endocytosed.
    F) Activation of a phosphodiesterase reduces intracellular cGMP and closes gates of cyclic nucleotide gated channels.

    Answer:
    D) Active rhodopsin is phosphorylated by opsin kinase and then inactived by arrestin.

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Introduction to Neuroscience Exam #3 (HST.131)

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Attribution:  Corey, David. HST.131 Introduction to Neuroscience, Fall 2005. (MIT OpenCourseWare: Massachusetts Institute of Technology), http://ocw.mit.edu/courses/health-sciences-and-technology/hst-131-introduction-to-neuroscience-fall-2005 (Accessed 12 Apr, 2014). License: Creative Commons BY-NC-SA
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