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The structure of chromosomes

Billions of cells in the human body divide every day. During the synthesis phase (S, for DNA synthesis) of interphase, the amount of DNA within the cell precisely doubles. Therefore, after DNA replication but before cell division, each cell actually contains two copies of each chromosome. Each copy of the chromosome is referred to as a sister chromatid    and is physically bound to the other copy. The centromere    is the structure that attaches one sister chromatid to another. Because a human cell has 46 chromosomes, during this phase, there are 92 chromatids (46 × 2) in the cell. Make sure not to confuse the concept of a pair of chromatids (one chromosome and its exact copy attached during mitosis) and a homologous pair of chromosomes (two paired chromosomes which were inherited separately, one from each parent) ( [link] ).

A homologous pair of chromosomes with their attached sister chromatids

This image shows a pair of chromosomes. The major parts such as the homologous chromosomes, kinetochore and the sister chromatids are labeled.
The red and blue colors correspond to a homologous pair of chromosomes. Each member of the pair was separately inherited from one parent. Each chromosome in the homologous pair is also bound to an identical sister chromatid, which is produced by DNA replication, and results in the familiar “X” shape.

Mitosis and cytokinesis

The mitotic phase    of the cell typically takes between 1 and 2 hours. During this phase, a cell undergoes two major processes. First, it completes mitosis, during which the contents of the nucleus are equitably pulled apart and distributed between its two halves. Cytokinesis then occurs, dividing the cytoplasm and cell body into two new cells. Mitosis is divided into four major stages that take place after interphase ( [link] ) and in the following order: prophase, metaphase, anaphase, and telophase. The process is then followed by cytokinesis.

Cell division: mitosis followed by cytokinesis

This tabular image shows the different stages of mitosis and cytokinesis using both drawings and text. The top panel is a series of schematics for each step, followed by text listing the important aspects of that step. The bottom panel shows fluorescent micrographs for the corresponding stage.
The stages of cell division oversee the separation of identical genetic material into two new nuclei, followed by the division of the cytoplasm.

Prophase is the first phase of mitosis, during which the loosely packed chromatin coils and condenses into visible chromosomes. During prophase, each chromosome becomes visible with its identical partner attached, forming the familiar X-shape of sister chromatids. The nucleolus disappears early during this phase, and the nuclear envelope also disintegrates.

A major occurrence during prophase concerns a very important structure that contains the origin site for microtubule growth. Recall the cellular structures called centrioles that serve as origin points from which microtubules extend. These tiny structures also play a very important role during mitosis. A centrosome    is a pair of centrioles together. The cell contains two centrosomes side-by-side, which begin to move apart during prophase. As the centrosomes migrate to two different sides of the cell, microtubules begin to extend from each like long fingers from two hands extending toward each other. The mitotic spindle    is the structure composed of the centrosomes and their emerging microtubules.

Questions & Answers

functions of connective tissue
renah Reply
what is a local potential
Nandi Reply
potential of neurons
vipin
response of neurons against sodium ion Chanel
vipin
The resting membrane potential of a neuron is about -70 mV (mV=millivolt) - this means that the inside of the neuron is 70 mV less than the outside. At rest, there are relatively more sodium ions outside the neuron and more potassium ions inside that neuron.
Adnan
what is tissues
Addai Reply
what is meant by control center?
Freeman Reply
what is anatomy
Ajibola Reply
is the study of the structure of the body and their relationship to each refers to the shapes iyo sizes
Khadar
If water touches hydrophobic tail, what will happen as negative effect?
Sayo
is the study of structural of the human body and their function
Masiame
What is the function of the Trachea
Samuel
what is a blastomere?
Toluba Reply
In biology, a blastomere is a type of cell produced by cleavage (cell division) of the zygote after fertilization and is an essential part of blastula formation.
Adnan
what is cell
Shivaani
Cells are the basic building blocks of all living things. The human body is composed of trillions of cells. They provide structure for the body, take in nutrients from food, convert those nutrients into energy, and carry out specialized functions. ... Cells have many parts, each with a different
Adnan
function
Adnan
cell is a membrane bound unit that contains the fundamentals molecules of life
Sushma
A1
Adnan
excellent
Adnan
movement,reproduction, excretion, respiration ,growth ,nutrition, response to external stimuli.
Sushma
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Adnan
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Adnan
questions pushy ja sukty hy kya
Maryam
jwab forun milta hy ya ak do din k bad
Maryam
Maryam Riaz sister what you say
Adnan
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Maryam
inshallah
Adnan
zaror mere behen
Adnan
question kari
Adnan
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Ziya
Which muscle of the gluteal region originates from lumber spine? a. Gluteus medius b. Psoas major c. Iliacus d. Gluteus maximus
Maryam
sweet sister's
Adnan
question tu kari Inshallah Allah behtar kariga
Adnan
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Maryam
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Maryam
wait sister
Adnan
what is the functional unit of kidneys
Khadar
nephron is the functional unit of kidney
Maryam
Maryam Riaz sister option. d. gluteus maximus
Adnan
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Maryam
sorry Maryam Riaz sister
Adnan
option b. psoas major
Adnan
right answer this one
Adnan
nephron is the functional unit of kidney
Ihsan
I discussed with to my teachers
Adnan
d
Ihsan
d. is right option bro
Adnan
yes
Ihsan
what is cell
Shilpa
cell is the smallest unit of life
Maryam
ok
Shilpa
Cells are the basic building blocks of all living things. The human body is composed of trillions of cells. They provide structure for the body, take in nutrients from food, convert those nutrients into energy, and carry out specialized functions. ... Cells have many parts, each with a different
Adnan
function
Adnan
Maryam Riaz sister I m clear option d. also right thank you ihan bro
Adnan
type structure function origin insertion action of muscles
DAMINI Reply
oxygn amount in our body
Tg Reply
A normal level of oxygen is usually 95% or higher. Some people with chronic lung disease or sleep apnea can have normal levels around 90%. The “SpO2” reading on a pulse oximeter shows the percentage of oxygen in someone's blood
Adnan
What is the difference between cytoplasmic and endoplasmic
Ajibola Reply
The cytoplasm is 90℅ water and 10℅ of organic and inorganic compounds. The cytoplasm contains mitochondria. ... Lysosomes of Cytoplasm contains 50 different enzymes that digest proteins, lipids, and nucleic acids. The endoplasmic reticulum produces process and transport proteins, lipids for all the
Adnan
tarsal are cube shaped broad and long whiles metatarsal they are longer than they are wide
Priscilla Reply
articular cartilage serve as shock absorber and also reduces friction
Priscilla
articular cartilage serve as shock absorber and also reduces friction
Priscilla
when a bone joint with another bone
Priscilla
to know how you body function to know the relationship between the body parts to know specific functions of a certain body parts
romeo Reply
To know our body function we shd know chemical secretion of our glands, we can map all the function of our body and also relation ship between the body parts.
KUSUMA
that z it kusuma
kanaku
can you get fungi infection by seating on a public toilet?
Calls Reply
explain how blood acts as a connective tissue in the body
Rymz Reply
how does blood act as a connective tissue in the body
Rymz
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Victoriah Reply
fat deficiency in the body
Agbor Reply

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Source:  OpenStax, Anatomy & Physiology. OpenStax CNX. Feb 04, 2016 Download for free at http://legacy.cnx.org/content/col11496/1.8
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