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Paired ovals, the testes are each approximately 4 to 5 cm in length and are housed within the scrotum (see [link] ). They are surrounded by two distinct layers of protective connective tissue ( [link] ). The outer tunica vaginalis is a serous membrane that has both a parietal and a thin visceral layer. Beneath the tunica vaginalis is the tunica albuginea, a tough, white, dense connective tissue layer covering the testis itself. Not only does the tunica albuginea cover the outside of the testis, it also invaginates to form septa that divide the testis into 300 to 400 structures called lobules. Within the lobules, sperm develop in structures called seminiferous tubules. During the seventh month of the developmental period of a male fetus, each testis moves through the abdominal musculature to descend into the scrotal cavity. This is called the “descent of the testis.” Cryptorchidism is the clinical term used when one or both of the testes fail to descend into the scrotum prior to birth.

Anatomy of the testis

This diagram shows the cross section of the testis.
This sagittal view shows the seminiferous tubules, the site of sperm production. Formed sperm are transferred to the epididymis, where they mature. They leave the epididymis during an ejaculation via the ductus deferens.

The tightly coiled seminiferous tubules    form the bulk of each testis. They are composed of developing sperm cells surrounding a lumen, the hollow center of the tubule, where formed sperm are released into the duct system of the testis. Specifically, from the lumens of the seminiferous tubules, sperm move into the straight tubules (or tubuli recti), and from there into a fine meshwork of tubules called the rete testes. Sperm leave the rete testes, and the testis itself, through the 15 to 20 efferent ductules that cross the tunica albuginea.

Inside the seminiferous tubules are six different cell types. These include supporting cells called sustentacular cells, as well as five types of developing sperm cells called germ cells. Germ cell development progresses from the basement membrane—at the perimeter of the tubule—toward the lumen. Let’s look more closely at these cell types.

Sertoli cells

Surrounding all stages of the developing sperm cells are elongate, branching Sertoli cells    . Sertoli cells are a type of supporting cell called a sustentacular cell, or sustenocyte, that are typically found in epithelial tissue. Sertoli cells secrete signaling molecules that promote sperm production and can control whether germ cells live or die. They extend physically around the germ cells from the peripheral basement membrane of the seminiferous tubules to the lumen. Tight junctions between these sustentacular cells create the blood–testis barrier    , which keeps bloodborne substances from reaching the germ cells and, at the same time, keeps surface antigens on developing germ cells from escaping into the bloodstream and prompting an autoimmune response.

Germ cells

The least mature cells, the spermatogonia    (singular = spermatogonium), line the basement membrane inside the tubule. Spermatogonia are the stem cells of the testis, which means that they are still able to differentiate into a variety of different cell types throughout adulthood. Spermatogonia divide to produce primary and secondary spermatocytes, then spermatids, which finally produce formed sperm. The process that begins with spermatogonia and concludes with the production of sperm is called spermatogenesis    .

Questions & Answers

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Esther Reply
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Austine
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Austine
Evening
Esther
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Melissa
evening
Vitus
what's the medulla?
alhussiney Reply
The medulla oblongata or simply medulla is a long stem-like structure which makes up the lower part of the brainstem. It is anterior and partially inferior to the cerebellum
Ludmila
define bone in simple terms
Mhoses Reply
bones are made up by collagen and calcium phosphate
Aurelia
yes
Confidence
Bones are the hard large calcareous connective tissue of which the adult skeleton of most vertebrates is chiefly composed
Olalekan
Bone is the substance that forms skeleton
Frances
good morning
Mrinal
Skelton muscles is any disorder of calcium
Mrinal
Bones protect the various organs of the body
Celina
A diagram of epithelial tissue
Emmanuel Reply
What does the urinary regulate blood pressure
Jennifer Reply
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marion Reply
d. inversely proportional
John Reply
Airway resistance in the human lung is? a. Greatest in the generation of distal bronchioles in healthy people because these airways have the smallest radii b. Not increased during a forced expiration in a healthy subject c. Decreased when breathing through the mouth d. Inversely proportional
Maryam Reply
1. Chemical level 2. Cellular level 3.Tissue level 4. Organ level 5.Organ system level 5.Organismal level
Jamela Reply
d
HMD
High
HMD
why there is bleeding in menstruation?
KUHELI Reply
menopause
Vasu
no
KUHELI
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Maryam
skin
The following hormones increase the blood glucose level except_____________? a. Parathormone b. Growth Hormone c. Epinephrine d. Thyroxine
Maryam
c.epinephrine
Divya
Which of the following is NOT a characteristic feature of alveoli in the lung? a. Poor blood supply b. A large surface area c. Thin walls d. Chemical layer called surfactant
Maryam
a.poor blood supply
Divya
poor blood supply
Tanvi
Excess of cortisol causes______________? a. Acromegaly b. Conn’s syndrome c. Diabetes insipidus d. Cushing syndrome
Maryam
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cushing syndrome
Tanvi
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Maryam
Airway resistance in the human lung is? a. Greatest in the generation of distal bronchioles in healthy people because these airways have the smallest radii b. Not increased during a forced expiration in a healthy subject c. Decreased when breathing through the mouth d. Inversely proportional
Maryam
what happens to the brain when one cannot sleep
aghedo
name temporary endocrine gland in female.
KUHELI Reply
when does 1st meiotic division occur in male ?
KUHELI Reply
spermatogenesis
Vasu
) Which of the following best describes the human body's defense mechanism against environmental bacteria?
Homeostasis
Zeinab
What the answer plz
Zeinab
skin
KUHELI
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Zeinab
Homeostasis is the system responsible for body response to external changes
Eliaz
skin
skin
Kharim
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Lodrick Reply
it's a reaction from a body tissue
Perpenjeng
is the body own mechanism of fighting against disease especially infections or injuries.
Azapa
Inflammation is a tissue response to damage tissues
Zeinab
The following hormones increase the blood glucose level except_____________? a. Parathormone b. Growth Hormone c. Epinephrine d. Thyroxine
Maryam
which cells are responsible for bone formation?
Richard Reply
osteocytes
Sharon
Oestocytes
Zeinab
osteocytes
Vasu
The following hormones increase the blood glucose level except_____________? a. Parathormone b. Growth Hormone c. Epinephrine d. Thyroxine
Maryam

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Source:  OpenStax, Anatomy & Physiology. OpenStax CNX. Feb 04, 2016 Download for free at http://legacy.cnx.org/content/col11496/1.8
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