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This presentation introduces the reader to the things to consider when finding fundingand was presented by Judith Greenberg (NIH).


  • Applying for an NIH grant: The basics
  • Special programs for early-career investigators
  • Resources

Applying for an nih grant: the basics

  • Start with a great idea!
    • Is it novel?
    • Does it address an important problem?
    • Will scientific knowledge be advanced? Will it move the field forward?
  • Be realistic, not overly ambitious
  • Write a focused, clear, understandable application; link hypotheses and approaches to specific aims - Presentation is important
  • Discuss rationale, potential obstacles, alternative approaches
  • Propose alternative interpretations; don’t appear too wedded to your hypothesis
  • Don’t assume reviewers know as much as you do about your project
  • Get advice from mentors; ask colleagues (outside your immediate research area) to read drafts
  • Learn as much as you can about the grants process
  • Look at study section descriptions and rosters (External Link) - you may request assignment
  • Find out whom to contact for information and when – program officer, grants management officer, scientific review officer
  • If you don’t get funded on the first try, don’t give up! Pay attention to critiques, and revise and resubmit

What is a new investigator?

  • Never had an R01 or equivalent grant from NIH
  • For some programs, must be within 10 years of latest degree

Special programs for early-career scientists

  • Kirschstein-NRSA Individual Fellowships (F32)
  • Career Development Awards (K)
  • NIH Director’s New Innovator Award (DP2)
  • NIH Research Supplements to Promote Diversity

Kirschstein-nrsa individual fellowships (f32)

  • Individual postdoctoral research training support
  • Must be US citizen, non-citizen national, or US permanent resident at time of award
  • Provides stipend and institutional allowance for up to 3 years
  • Research supervised by faculty mentor

Selected career development awards (k)

  • To provide support and “protected time” (3-5 years) for an intensive, supervised career development experience in the biomedical, behavioral, or clinical sciences leading to research independence
  • To provide support for newly independent scientists who can demonstrate the need for a period of intensive research focus as a means of enhancing their research careers
  • To provide support and “protected time” to individuals with a clinical doctoral degree for an intensive, supervised research career development experience in the fields of biomedical and behavioral research, including translational research
  • To attract to NIH-relevant research those investigators whose quantitative science and engineering research has thus far not been focused primarily on questions of health and disease
  • To provide an opportunity for promising postdoctoral scientists to receive both mentored and independent research support from the same award

Pathway to independence award (k99/r00)

  • Designed to facilitate a timely transition from a mentored postdoctoral research position to a stable independent research position at an earlier stage than the norm
  • Up to 5 years of support consisting of 2 phases
  • Phase I provides 1-2 years of mentored support for highly promising, postdoctoral research scientists
  • Phase II provides up to 3 years of independent support contingent on securing an independent research position

Nih director’s new innovator award (dp2)

  • To stimulate highly innovative research
  • To support promising new investigators
  • One application receipt period per year
  • 10-page application
  • Awards provide up to $1.5 million in direct costs for 5 year project period

Nih research supplements to promote diversity

  • For individuals from under-represented groups or disadvantaged background
  • Provides supplements to R01 and other grant mechanisms to support individuals at various career stages from high school through investigator

But remember...

The R01 is still the major source of support for early-career investigators and is the “gold-standard.”

Some good news for new investigators

  • NIH has set a target for the number of awards to new investigators
  • NIH Enhancing Peer Review Report (2008) also recommends
    • Establishing an Early Stage Investigator (ESI) designation
    • Clustering the reviews of ESI applications

Web resources – read and ask questions

  • (External Link) – contains many documents explaining grant processes, mechanisms, special programs, tips for writing applications
  • (External Link)
  • (External Link) - lets you search abstracts of funded grants
  • (External Link) – announces special programs and initiatives
  • (External Link) - lets you see what reviewers are looking for (note links for review of applications from new investigators and for specific grant mechanisms)

And don't forget...

  • Contact NIH program officers – identify from NIH home page (External Link)
  • Talk to your institution’s sponsored research office
  • Consult your former advisers and current senior colleagues

Questions & Answers

where we get a research paper on Nano chemistry....?
Maira Reply
nanopartical of organic/inorganic / physical chemistry , pdf / thesis / review
what are the products of Nano chemistry?
Maira Reply
There are lots of products of nano chemistry... Like nano coatings.....carbon fiber.. And lots of others..
Even nanotechnology is pretty much all about chemistry... Its the chemistry on quantum or atomic level
no nanotechnology is also a part of physics and maths it requires angle formulas and some pressure regarding concepts
Preparation and Applications of Nanomaterial for Drug Delivery
Hafiz Reply
Application of nanotechnology in medicine
what is variations in raman spectra for nanomaterials
Jyoti Reply
ya I also want to know the raman spectra
I only see partial conversation and what's the question here!
Crow Reply
what about nanotechnology for water purification
RAW Reply
please someone correct me if I'm wrong but I think one can use nanoparticles, specially silver nanoparticles for water treatment.
yes that's correct
I think
Nasa has use it in the 60's, copper as water purification in the moon travel.
nanocopper obvius
what is the stm
Brian Reply
is there industrial application of fullrenes. What is the method to prepare fullrene on large scale.?
industrial application...? mmm I think on the medical side as drug carrier, but you should go deeper on your research, I may be wrong
How we are making nano material?
what is a peer
What is meant by 'nano scale'?
What is STMs full form?
scanning tunneling microscope
how nano science is used for hydrophobicity
Do u think that Graphene and Fullrene fiber can be used to make Air Plane body structure the lightest and strongest. Rafiq
what is differents between GO and RGO?
what is simplest way to understand the applications of nano robots used to detect the cancer affected cell of human body.? How this robot is carried to required site of body cell.? what will be the carrier material and how can be detected that correct delivery of drug is done Rafiq
analytical skills graphene is prepared to kill any type viruses .
Any one who tell me about Preparation and application of Nanomaterial for drug Delivery
what is Nano technology ?
Bob Reply
write examples of Nano molecule?
The nanotechnology is as new science, to scale nanometric
nanotechnology is the study, desing, synthesis, manipulation and application of materials and functional systems through control of matter at nanoscale
Is there any normative that regulates the use of silver nanoparticles?
Damian Reply
what king of growth are you checking .?
What fields keep nano created devices from performing or assimulating ? Magnetic fields ? Are do they assimilate ?
Stoney Reply
why we need to study biomolecules, molecular biology in nanotechnology?
Adin Reply
yes I'm doing my masters in nanotechnology, we are being studying all these domains as well..
what school?
biomolecules are e building blocks of every organics and inorganic materials.
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Source:  OpenStax, 2008 nsf advance workshop: negotiating the ideal faculty position. OpenStax CNX. Feb 24, 2010 Download for free at http://cnx.org/content/col10628/1.3
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