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This presentation introduces the reader to the things to consider when finding fundingand was presented by Judith Greenberg (NIH).


  • Applying for an NIH grant: The basics
  • Special programs for early-career investigators
  • Resources

Applying for an nih grant: the basics

  • Start with a great idea!
    • Is it novel?
    • Does it address an important problem?
    • Will scientific knowledge be advanced? Will it move the field forward?
  • Be realistic, not overly ambitious
  • Write a focused, clear, understandable application; link hypotheses and approaches to specific aims - Presentation is important
  • Discuss rationale, potential obstacles, alternative approaches
  • Propose alternative interpretations; don’t appear too wedded to your hypothesis
  • Don’t assume reviewers know as much as you do about your project
  • Get advice from mentors; ask colleagues (outside your immediate research area) to read drafts
  • Learn as much as you can about the grants process
  • Look at study section descriptions and rosters (External Link) - you may request assignment
  • Find out whom to contact for information and when – program officer, grants management officer, scientific review officer
  • If you don’t get funded on the first try, don’t give up! Pay attention to critiques, and revise and resubmit

What is a new investigator?

  • Never had an R01 or equivalent grant from NIH
  • For some programs, must be within 10 years of latest degree

Special programs for early-career scientists

  • Kirschstein-NRSA Individual Fellowships (F32)
  • Career Development Awards (K)
  • NIH Director’s New Innovator Award (DP2)
  • NIH Research Supplements to Promote Diversity

Kirschstein-nrsa individual fellowships (f32)

  • Individual postdoctoral research training support
  • Must be US citizen, non-citizen national, or US permanent resident at time of award
  • Provides stipend and institutional allowance for up to 3 years
  • Research supervised by faculty mentor

Selected career development awards (k)

  • To provide support and “protected time” (3-5 years) for an intensive, supervised career development experience in the biomedical, behavioral, or clinical sciences leading to research independence
  • To provide support for newly independent scientists who can demonstrate the need for a period of intensive research focus as a means of enhancing their research careers
  • To provide support and “protected time” to individuals with a clinical doctoral degree for an intensive, supervised research career development experience in the fields of biomedical and behavioral research, including translational research
  • To attract to NIH-relevant research those investigators whose quantitative science and engineering research has thus far not been focused primarily on questions of health and disease
  • To provide an opportunity for promising postdoctoral scientists to receive both mentored and independent research support from the same award

Pathway to independence award (k99/r00)

  • Designed to facilitate a timely transition from a mentored postdoctoral research position to a stable independent research position at an earlier stage than the norm
  • Up to 5 years of support consisting of 2 phases
  • Phase I provides 1-2 years of mentored support for highly promising, postdoctoral research scientists
  • Phase II provides up to 3 years of independent support contingent on securing an independent research position

Nih director’s new innovator award (dp2)

  • To stimulate highly innovative research
  • To support promising new investigators
  • One application receipt period per year
  • 10-page application
  • Awards provide up to $1.5 million in direct costs for 5 year project period

Nih research supplements to promote diversity

  • For individuals from under-represented groups or disadvantaged background
  • Provides supplements to R01 and other grant mechanisms to support individuals at various career stages from high school through investigator

But remember...

The R01 is still the major source of support for early-career investigators and is the “gold-standard.”

Some good news for new investigators

  • NIH has set a target for the number of awards to new investigators
  • NIH Enhancing Peer Review Report (2008) also recommends
    • Establishing an Early Stage Investigator (ESI) designation
    • Clustering the reviews of ESI applications

Web resources – read and ask questions

  • (External Link) – contains many documents explaining grant processes, mechanisms, special programs, tips for writing applications
  • (External Link)
  • (External Link) - lets you search abstracts of funded grants
  • (External Link) – announces special programs and initiatives
  • (External Link) - lets you see what reviewers are looking for (note links for review of applications from new investigators and for specific grant mechanisms)

And don't forget...

  • Contact NIH program officers – identify from NIH home page (External Link)
  • Talk to your institution’s sponsored research office
  • Consult your former advisers and current senior colleagues

Questions & Answers

What fields keep nano created devices from performing or assimulating ? Magnetic fields ? Are do they assimilate ?
Stoney Reply
why we need to study biomolecules, molecular biology in nanotechnology?
Adin Reply
yes I'm doing my masters in nanotechnology, we are being studying all these domains as well..
what school?
biomolecules are e building blocks of every organics and inorganic materials.
anyone know any internet site where one can find nanotechnology papers?
Damian Reply
sciencedirect big data base
Introduction about quantum dots in nanotechnology
Praveena Reply
what does nano mean?
Anassong Reply
nano basically means 10^(-9). nanometer is a unit to measure length.
do you think it's worthwhile in the long term to study the effects and possibilities of nanotechnology on viral treatment?
Damian Reply
absolutely yes
how to know photocatalytic properties of tio2 nanoparticles...what to do now
Akash Reply
it is a goid question and i want to know the answer as well
characteristics of micro business
for teaching engĺish at school how nano technology help us
Do somebody tell me a best nano engineering book for beginners?
s. Reply
there is no specific books for beginners but there is book called principle of nanotechnology
what is fullerene does it is used to make bukky balls
Devang Reply
are you nano engineer ?
fullerene is a bucky ball aka Carbon 60 molecule. It was name by the architect Fuller. He design the geodesic dome. it resembles a soccer ball.
what is the actual application of fullerenes nowadays?
That is a great question Damian. best way to answer that question is to Google it. there are hundreds of applications for buck minister fullerenes, from medical to aerospace. you can also find plenty of research papers that will give you great detail on the potential applications of fullerenes.
what is the Synthesis, properties,and applications of carbon nano chemistry
Abhijith Reply
Mostly, they use nano carbon for electronics and for materials to be strengthened.
is Bucky paper clear?
carbon nanotubes has various application in fuel cells membrane, current research on cancer drug,and in electronics MEMS and NEMS etc
so some one know about replacing silicon atom with phosphorous in semiconductors device?
s. Reply
Yeah, it is a pain to say the least. You basically have to heat the substarte up to around 1000 degrees celcius then pass phosphene gas over top of it, which is explosive and toxic by the way, under very low pressure.
Do you know which machine is used to that process?
how to fabricate graphene ink ?
for screen printed electrodes ?
What is lattice structure?
s. Reply
of graphene you mean?
or in general
in general
Graphene has a hexagonal structure
On having this app for quite a bit time, Haven't realised there's a chat room in it.
what is biological synthesis of nanoparticles
Sanket Reply
what's the easiest and fastest way to the synthesize AgNP?
Damian Reply
how did you get the value of 2000N.What calculations are needed to arrive at it
Smarajit Reply
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Source:  OpenStax, 2008 nsf advance workshop: negotiating the ideal faculty position. OpenStax CNX. Feb 24, 2010 Download for free at http://cnx.org/content/col10628/1.3
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