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Phospolipid bilayer

This diagram shows a phospholipid bilayer. Two sets of phospholipids are arranged such that the hydrophobic tails are facing each other and the hydrophilic heads are facing the extracellular environment.
The phospholipid bilayer consists of two adjacent sheets of phospholipids, arranged tail to tail. The hydrophobic tails associate with one another, forming the interior of the membrane. The polar heads contact the fluid inside and outside of the cell.

Membrane proteins

The lipid bilayer forms the basis of the cell membrane, but it is peppered throughout with various proteins. Two different types of proteins that are commonly associated with the cell membrane are the integral proteins and peripheral protein ( [link] ). As its name suggests, an integral protein    is a protein that is embedded in the membrane. A channel protein    is an example of an integral protein that selectively allows particular materials, such as certain ions, to pass into or out of the cell.

Cell membrane

This image shows a lipid bilayer with different types of proteins, lipids and cholesterol embedded in it.
The cell membrane of the cell is a phospholipid bilayer containing many different molecular components, including proteins and cholesterol, some with carbohydrate groups attached.

Another important group of integral proteins are cell recognition proteins, which serve to mark a cell’s identity so that it can be recognized by other cells. A receptor    is a type of recognition protein that can selectively bind a specific molecule outside the cell, and this binding induces a chemical reaction within the cell. A ligand    is the specific molecule that binds to and activates a receptor. Some integral proteins serve dual roles as both a receptor and an ion channel. One example of a receptor-ligand interaction is the receptors on nerve cells that bind neurotransmitters, such as dopamine. When a dopamine molecule binds to a dopamine receptor protein, a channel within the transmembrane protein opens to allow certain ions to flow into the cell.

Some integral membrane proteins are glycoproteins. A glycoprotein    is a protein that has carbohydrate molecules attached, which extend into the extracellular matrix. The attached carbohydrate tags on glycoproteins aid in cell recognition. The carbohydrates that extend from membrane proteins and even from some membrane lipids collectively form the glycocalyx. The glycocalyx    is a fuzzy-appearing coating around the cell formed from glycoproteins and other carbohydrates attached to the cell membrane. The glycocalyx can have various roles. For example, it may have molecules that allow the cell to bind to another cell, it may contain receptors for hormones, or it might have enzymes to break down nutrients. The glycocalyces found in a person’s body are products of that person’s genetic makeup. They give each of the individual’s trillions of cells the “identity” of belonging in the person’s body. This identity is the primary way that a person’s immune defense cells “know” not to attack the person’s own body cells, but it also is the reason organs donated by another person might be rejected.

Peripheral proteins are typically found on the inner or outer surface of the lipid bilayer but can also be attached to the internal or external surface of an integral protein. These proteins typically perform a specific function for the cell. Some peripheral proteins on the surface of intestinal cells, for example, act as digestive enzymes to break down nutrients to sizes that can pass through the cells and into the bloodstream.

Questions & Answers

why human blood pressure high
amin Reply
What is red blood cell
HANNAH Reply
A type of blood cell that is made in the bone marrow and found in the blood. Red blood cells contain a protein called hemoglobin, which carries oxygen from the lungs to all parts of the body. Checking the number of red blood cells in the blood is usually part of a complete blood cell (CBC) test. It
Noor
red blood cell are the most numerous blood cells.they comprise about 99% of all blood cells red blood cells are non nucleated it has red colour due to present to hemoglobin.
Vineeta
Thanks for the answers
HANNAH
how will you promote quality of life in ptb patient using the 14 basic needs and 21 nursing problems?
rOx Reply
coronary circulation ?
Juri Reply
Coronary circulation is the circulation of blood in the blood vessels that supply the heart muscle (myocardium). Coronary arteries supply oxygenated blood to the heart muscle, and cardiac veins drain away the blood once it has been deoxygenated. Because the rest of the body.
Riyaz
coronary circulation ,is flow of blood that supplies the heart tissue itself is the coronary circulation. the functional blood supply of the heart,is the shortest circulation in tha body.
Vineeta
what about the easy way to understand action potential
Bright
event of cardiac cycle
Juri Reply
hii
Chandan
whatisanatom
kaso Reply
anatomy is the scientific way of studying the body structure.
cynthia
the branch of science concerned with the bodily structure of humans, animals, and other living organisms, especially as revealed by dissection and the separation of parts.
Noor
what is means by LAPE and HAPE
Noor
guys i've question what occur when homeostasis balance mechanisms lost
cris Reply
Bladder is blank to the small intestine, what is the right directional term for that?
Julaika Reply
When peristaltic movement is correct.
Farid
what tissue that support body organ?
Sabrina Reply
the skeleton
veronica
Skeleton
GEBAH
skeleton
Juwita
skeleton
Farid
skeleton
Priya
skeleton
Emmanuel
skeleton
Noor
skeleton
BILAL
skeleton
hanuman
how many bones are there in the body
hanuman Reply
go uuu
Prasad
206
Prasad
206
Nelago
206
Esmeralda
206
Joey
baby me 360. and human body 206.found bones.....
Sneha
what is a tissue in Anatomy and physiology
Nelago
206 bones
Juwita
what is an example of a molecule that can directly pass through the phospholipid bilayer of the plasma membrane?
Kathy
206
Johara
how many bones are there in the hand and wrist
hanuman
200 tissue
hanuman
answer 206 bones
GEBAH
axial 80 appendicular 126 total bone is 206
Vineeta
wrist bone 8
Vineeta
baby bone 270 he is correct answer
hanuman
Jo carpus wrist bone h
Vineeta
206
Musonda
206 bones in human body.
Farid
What is Heart attack?
Farid
206
Priti
206 all
Sa
All 206
Sa
A heart attack happens when the flow of oxygen-rich blood to a section of heart muscle suddenly becomes blocked and the heart can't get oxygen. If blood flow isn't restored quickly, the section of heart muscle begins to die. Heart attack treatment works best when it's given right after symptoms occu
Riyaz
how can l understand Anatomy quickly?
Agness Reply
you can't!!!! Anatomy is easy but the physiology takes time to understand. Anatomy is simply systems and organs but you must take time to learn physiology to understand how the anatomy works
Rachael
alright.. so how can l at least memorize the information about physiology?
Agness
what name is given to the fluid that is drawn from the villi to the lymphatic vessels
margaret Reply
I think venous
Noor
lymph
Rachael
I also think it's lymph
Akhi
me too I think lymph
Esmeralda
ans Rhythmic contraction
GEBAH
what are the ten (10) rights for drug administration
GEBAH
importance of muscle in the anatomical structures.
Akomeng Reply
it permits the constant level of movement,and gives structure and shape to the body
Priya
what is assimilation
Asiimwe Reply
cellular level organism level chemical level organ system level tissue level organ level
Aleah Reply
, the current topic
Hilya
cellular level
Priya
tissue level
Priya
organ level
Priya
organ systems level
Priya
organism level
Priya

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Source:  OpenStax, Anatomy & Physiology. OpenStax CNX. Feb 04, 2016 Download for free at http://legacy.cnx.org/content/col11496/1.8
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