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In bioinformatics, many of the major service providers are providing Web Service interfaces to their resources, including the NCBI, EBI, and DDBJ; many more are embracing this technology each year. This widespread adoption of Web Services has enabled workflows to be more commonly used within scientific research. Data held in the NCBI can now be analysed with tools available at the EBI, within analysis pipeline.

In silico workflows

One possible solution to the problem of integrating heterogeneous resources is the use of in silico workflows. The use of workflows in science has only emerged over the last few years and addresses different concerns to workflows used within the business sector. Rather than co-ordinating the management and transactions between corporate resources, scientific workflows are used to automate the analysis of data through multiple, distributed data resources in order to execute complex in silico experiments.

Workflows provide a mechanism for accessing remote third-party services and components. This in turn reduces the overheads of downloading, installing, and maintaining resources locally whilst ensuring access to the latest versions of data and tools. Additionally, much of the computation happens remotely (on dedicated servers). This allows complex and computationally intensive workflows to be executed from basic desktop or laptop computers. As a result, the researchers are not held back by a lack of computational resources or access to data.

A workflow provides an abstracted view over the experiment being performed. It describes what analyses will be executed, not the low-level details of how they will be executed; the user does not need to understand the underlying code, but only the scientific protocol. This protocol can be easily understood by others, so can be reused or even altered and repurposed. Workflows are a suitable technology in any case where scientists need to automate data processing through a series of analysis steps. Such mechanisms have the potential to increase the rate of data analysis, from a cottage-scale to industrial scale operation.

There are many workflow management systems available in the scientific domain, including: Taverna (Hull et al . 2006), Kepler (Altintas et al. 2004) and Triana (Taylor et al. 2003). Taverna, developed by the the myGrid consortium (http://www.mygrid.org.uk/), is a workflow system that was built with the Life Sciences in mind but it has since been used in other fields as well, including Physics, Astronomy and Chemistry. Like many others, the Taverna Workbench provides:

  • an environment for designing workflows;
  • an enactment engine to execute workflow locally or remotely;
  • support for workflow design in the form of service and workflow discovery;
  • and provenance services to manage the results and events of workflow invocations.

Understanding disease resistance in model organisms

Taverna workflows are used in many areas of Life Science research, notably for research into genotype-phenotype correlations, proteomics, genome annotation, and Systems Biology. The following case study demonstrates the use of Taverna workflows in the Life Sciences domain for genotype-phenotype studies (Stevens et al . 2008).

Questions & Answers

what is math number
Tric Reply
x-2y+3z=-3 2x-y+z=7 -x+3y-z=6
Sidiki Reply
Need help solving this problem (2/7)^-2
Simone Reply
what is the coefficient of -4×
Mehri Reply
the operation * is x * y =x + y/ 1+(x × y) show if the operation is commutative if x × y is not equal to -1
Alfred Reply
An investment account was opened with an initial deposit of $9,600 and earns 7.4% interest, compounded continuously. How much will the account be worth after 15 years?
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lim x to infinity e^1-e^-1/log(1+x)
given eccentricity and a point find the equiation
Moses Reply
12, 17, 22.... 25th term
Alexandra Reply
12, 17, 22.... 25th term
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Absolutely, for me. My problems with math started in First grade...involving a nun Sister Anastasia, bad vision, talking & getting expelled from Catholic school. When it comes to math I just can't focus and all I can hear is our family silverware banging and clanging on the pink Formica table.
I'm 13 and I understand it great
I am 1 year old but I can do it! 1+1=2 proof very hard for me though.
Not really they are just easy concepts which can be understood if you have great basics. I am 14 I understood them easily.
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find the 15th term of the geometric sequince whose first is 18 and last term of 387
Jerwin Reply
I know this work
The given of f(x=x-2. then what is the value of this f(3) 5f(x+1)
virgelyn Reply
hmm well what is the answer
If f(x) = x-2 then, f(3) when 5f(x+1) 5((3-2)+1) 5(1+1) 5(2) 10
how do they get the third part x = (32)5/4
kinnecy Reply
make 5/4 into a mixed number, make that a decimal, and then multiply 32 by the decimal 5/4 turns out to be
can someone help me with some logarithmic and exponential equations.
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I'm not sure why it wrote it the other way
I got X =-6
ok. so take the square root of both sides, now you have plus or minus the square root of 20= x-6
oops. ignore that.
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Commplementary angles
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A soccer field is a rectangle 130 meters wide and 110 meters long. The coach asks players to run from one corner to the other corner diagonally across. What is that distance, to the nearest tenths place.
Kimberly Reply
Jeannette has $5 and $10 bills in her wallet. The number of fives is three more than six times the number of tens. Let t represent the number of tens. Write an expression for the number of fives.
August Reply
What is the expressiin for seven less than four times the number of nickels
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How do i figure this problem out.
how do you translate this in Algebraic Expressions
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why surface tension is zero at critical temperature
I think if critical temperature denote high temperature then a liquid stats boils that time the water stats to evaporate so some moles of h2o to up and due to high temp the bonding break they have low density so it can be a reason
Need to simplify the expresin. 3/7 (x+y)-1/7 (x-1)=
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. After 3 months on a diet, Lisa had lost 12% of her original weight. She lost 21 pounds. What was Lisa's original weight?
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Source:  OpenStax, Research in a connected world. OpenStax CNX. Nov 22, 2009 Download for free at http://cnx.org/content/col10677/1.12
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