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In bioinformatics, many of the major service providers are providing Web Service interfaces to their resources, including the NCBI, EBI, and DDBJ; many more are embracing this technology each year. This widespread adoption of Web Services has enabled workflows to be more commonly used within scientific research. Data held in the NCBI can now be analysed with tools available at the EBI, within analysis pipeline.

In silico workflows

One possible solution to the problem of integrating heterogeneous resources is the use of in silico workflows. The use of workflows in science has only emerged over the last few years and addresses different concerns to workflows used within the business sector. Rather than co-ordinating the management and transactions between corporate resources, scientific workflows are used to automate the analysis of data through multiple, distributed data resources in order to execute complex in silico experiments.

Workflows provide a mechanism for accessing remote third-party services and components. This in turn reduces the overheads of downloading, installing, and maintaining resources locally whilst ensuring access to the latest versions of data and tools. Additionally, much of the computation happens remotely (on dedicated servers). This allows complex and computationally intensive workflows to be executed from basic desktop or laptop computers. As a result, the researchers are not held back by a lack of computational resources or access to data.

A workflow provides an abstracted view over the experiment being performed. It describes what analyses will be executed, not the low-level details of how they will be executed; the user does not need to understand the underlying code, but only the scientific protocol. This protocol can be easily understood by others, so can be reused or even altered and repurposed. Workflows are a suitable technology in any case where scientists need to automate data processing through a series of analysis steps. Such mechanisms have the potential to increase the rate of data analysis, from a cottage-scale to industrial scale operation.

There are many workflow management systems available in the scientific domain, including: Taverna (Hull et al . 2006), Kepler (Altintas et al. 2004) and Triana (Taylor et al. 2003). Taverna, developed by the the myGrid consortium (http://www.mygrid.org.uk/), is a workflow system that was built with the Life Sciences in mind but it has since been used in other fields as well, including Physics, Astronomy and Chemistry. Like many others, the Taverna Workbench provides:

  • an environment for designing workflows;
  • an enactment engine to execute workflow locally or remotely;
  • support for workflow design in the form of service and workflow discovery;
  • and provenance services to manage the results and events of workflow invocations.

Understanding disease resistance in model organisms

Taverna workflows are used in many areas of Life Science research, notably for research into genotype-phenotype correlations, proteomics, genome annotation, and Systems Biology. The following case study demonstrates the use of Taverna workflows in the Life Sciences domain for genotype-phenotype studies (Stevens et al . 2008).

Questions & Answers

where we get a research paper on Nano chemistry....?
Maira Reply
nanopartical of organic/inorganic / physical chemistry , pdf / thesis / review
Ali
what are the products of Nano chemistry?
Maira Reply
There are lots of products of nano chemistry... Like nano coatings.....carbon fiber.. And lots of others..
learn
Even nanotechnology is pretty much all about chemistry... Its the chemistry on quantum or atomic level
learn
Google
da
no nanotechnology is also a part of physics and maths it requires angle formulas and some pressure regarding concepts
Bhagvanji
hey
Giriraj
Preparation and Applications of Nanomaterial for Drug Delivery
Hafiz Reply
revolt
da
Application of nanotechnology in medicine
what is variations in raman spectra for nanomaterials
Jyoti Reply
I only see partial conversation and what's the question here!
Crow Reply
what about nanotechnology for water purification
RAW Reply
please someone correct me if I'm wrong but I think one can use nanoparticles, specially silver nanoparticles for water treatment.
Damian
yes that's correct
Professor
I think
Professor
Nasa has use it in the 60's, copper as water purification in the moon travel.
Alexandre
nanocopper obvius
Alexandre
what is the stm
Brian Reply
is there industrial application of fullrenes. What is the method to prepare fullrene on large scale.?
Rafiq
industrial application...? mmm I think on the medical side as drug carrier, but you should go deeper on your research, I may be wrong
Damian
How we are making nano material?
LITNING Reply
what is a peer
LITNING Reply
What is meant by 'nano scale'?
LITNING Reply
What is STMs full form?
LITNING
scanning tunneling microscope
Sahil
how nano science is used for hydrophobicity
Santosh
Do u think that Graphene and Fullrene fiber can be used to make Air Plane body structure the lightest and strongest. Rafiq
Rafiq
what is differents between GO and RGO?
Mahi
what is simplest way to understand the applications of nano robots used to detect the cancer affected cell of human body.? How this robot is carried to required site of body cell.? what will be the carrier material and how can be detected that correct delivery of drug is done Rafiq
Rafiq
if virus is killing to make ARTIFICIAL DNA OF GRAPHENE FOR KILLED THE VIRUS .THIS IS OUR ASSUMPTION
Anam
analytical skills graphene is prepared to kill any type viruses .
Anam
Any one who tell me about Preparation and application of Nanomaterial for drug Delivery
Hafiz
what is Nano technology ?
Bob Reply
write examples of Nano molecule?
Bob
The nanotechnology is as new science, to scale nanometric
brayan
nanotechnology is the study, desing, synthesis, manipulation and application of materials and functional systems through control of matter at nanoscale
Damian
Is there any normative that regulates the use of silver nanoparticles?
Damian Reply
what king of growth are you checking .?
Renato
What fields keep nano created devices from performing or assimulating ? Magnetic fields ? Are do they assimilate ?
Stoney Reply
why we need to study biomolecules, molecular biology in nanotechnology?
Adin Reply
?
Kyle
yes I'm doing my masters in nanotechnology, we are being studying all these domains as well..
Adin
why?
Adin
what school?
Kyle
biomolecules are e building blocks of every organics and inorganic materials.
Joe
how did you get the value of 2000N.What calculations are needed to arrive at it
Smarajit Reply
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Source:  OpenStax, Research in a connected world. OpenStax CNX. Nov 22, 2009 Download for free at http://cnx.org/content/col10677/1.12
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