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Area calculation

With the accumulation array, we were able to extrapolate the sizes of the individual cells and it was determined that the average cell size in our image is roughly 150um2.

But what does it all mean?

When imaging techniques become more advanced, it is our hope that not only would we be able to calculate the size of the cells, but the nucleus as well. By being able to calculate both the cell sizes as well as the nucleus, the ratio between the two can be determined. This can then be used as a completely non-invasive detector of cancer, with higher nucleus-to-cell ratios being indicative of the presence of cancer.


Our area calculation is far from perfect and, with time, there are many improvements which can be made.

Image acquisition

The image acquisition technique can be improved to not only be able to detect the nucleus, but to provide better definition between a cell’s border and the background as well. But… this we will leave to our bioengineering friends.

Edge detection

In our edge detection phase, one problem we faced was the varying thickness of cell borders. Sometimes, especially thick borders would appear as a closed region resembling a cell when edge detection is performed! This problem, however, we believe can be rectified using carefully constructed filters which can hopefully reduce the thickness of borders.

Circle detection

The Hough Transform we used approximates cell sizes using the approximate circles. Cells, however, are not always completely circular. A more generalized transform can be employed to more precisely detect the shape of the cells and give a more precise area calculation.

Questions & Answers

anyone have book of Abdel Salam Hamdy Makhlouf book in pdf Fundamentals of Nanoparticles: Classifications, Synthesis
Naeem Reply
what happen with The nano material on The deep space.?
pedro Reply
It could change the whole space science.
the characteristics of nano materials can be studied by solving which equation?
sibaram Reply
plz answer fast
synthesis of nano materials by chemical reaction taking place in aqueous solvents under high temperature and pressure is call?
hydrothermal synthesis
how can chip be made from sand
Eke Reply
is this allso about nanoscale material
are nano particles real
Missy Reply
Hello, if I study Physics teacher in bachelor, can I study Nanotechnology in master?
Lale Reply
no can't
where is the latest information on a no technology how can I find it
where we get a research paper on Nano chemistry....?
Maira Reply
nanopartical of organic/inorganic / physical chemistry , pdf / thesis / review
what are the products of Nano chemistry?
Maira Reply
There are lots of products of nano chemistry... Like nano coatings.....carbon fiber.. And lots of others..
Even nanotechnology is pretty much all about chemistry... Its the chemistry on quantum or atomic level
no nanotechnology is also a part of physics and maths it requires angle formulas and some pressure regarding concepts
Preparation and Applications of Nanomaterial for Drug Delivery
Hafiz Reply
Application of nanotechnology in medicine
has a lot of application modern world
what is variations in raman spectra for nanomaterials
Jyoti Reply
ya I also want to know the raman spectra
I only see partial conversation and what's the question here!
Crow Reply
what about nanotechnology for water purification
RAW Reply
please someone correct me if I'm wrong but I think one can use nanoparticles, specially silver nanoparticles for water treatment.
yes that's correct
I think
Nasa has use it in the 60's, copper as water purification in the moon travel.
nanocopper obvius
what is the stm
Brian Reply
is there industrial application of fullrenes. What is the method to prepare fullrene on large scale.?
industrial application...? mmm I think on the medical side as drug carrier, but you should go deeper on your research, I may be wrong
STM - Scanning Tunneling Microscope.
How we are making nano material?
Some times this process occur naturally. if not, nano engineers build nano materials. they have different physical and chemical properties.
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Source:  OpenStax, Detection of cell boundaries in optical fiber probe images. OpenStax CNX. Jan 20, 2008 Download for free at http://cnx.org/content/col10501/1.2
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