• Card 6 / 11: The following information is for Questions 4?-5 The 1 year risk (i.e. annual incidence) of lung cancer in smokers is 140 per 100,000. The 1 year risk of lung cancer in non?-smokers of the general population is 10 per 100,000.Calculate and interpret the odds ratio describing the association between smoking and lung cancer.

    Answer:
    Putting the numbers in a 2x2 table format is easiest to calculate an OR A=140 B=99,860 OR=AD/BC or 140*99,990 / 10*99,860 = 14 C=10 D=99,990 Interpretation: over 1 year, smokers are 14 times as likely to develop lung cancer as non?-smokers Note: The OR is interpreted in exactly the same way as a RR.

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Epidemiology & Biostatistics Cohort Studies

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Attribution:  Janet, E.A. Forrester, Kwan Ho Kenneth Chui, Steven Cohen, Michael D. Kneeland, Alice Tang, David Tybor. Epidemiology and Biostatistics 2010. (Tufts University OpenCourseWare), http://ocw.tufts.edu/Course/65/ (Accessed 3 May, 2014). License: Creative Commons BY-NC-SA
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