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By the end of this section, you will be able to:
  • Describe the three stages of interphase
  • Discuss the behavior of chromosomes during karyokinesis
  • Explain how the cytoplasmic content is divided during cytokinesis
  • Define the quiescent G 0 phase

The cell cycle    is an ordered series of events involving cell growth and cell division that produces two new daughter cells. Cells on the path to cell division proceed through a series of precisely timed and carefully regulated stages of growth, DNA replication, and division that produces two identical (clone) cells. The cell cycle has two major phases: interphase and the mitotic phase ( [link] ). During interphase    , the cell grows and DNA is replicated. During the mitotic phase    , the replicated DNA and cytoplasmic contents are separated, and the cell divides.

Like a clock, the cell cycles from interphase to the mitotic phase and back to interphase. Most of the cell cycle is spent in interphase, which is subdivided into G_{1}, S, and G_{2} phases. Cell growth occurs during G_{1}, DNA synthesis occurs during S, and more growth occurs during G_{2}. The mitotic phase consists of mitosis, in which the nuclear chromatin is divided, and cytokinesis, in which the cytoplasm is divided, resulting in two daughter cells.
The cell cycle consists of interphase and the mitotic phase. During interphase, the cell grows and the nuclear DNA is duplicated. Interphase is followed by the mitotic phase. During the mitotic phase, the duplicated chromosomes are segregated and distributed into daughter nuclei. The cytoplasm is usually divided as well, resulting in two daughter cells.

Interphase

During interphase, the cell undergoes normal growth processes while also preparing for cell division. In order for a cell to move from interphase into the mitotic phase, many internal and external conditions must be met. The three stages of interphase are called G 1 , S, and G 2 .

G 1 Phase (first gap)

The first stage of interphase is called the G 1 phase    (first gap) because, from a microscopic aspect, little change is visible. However, during the G 1 stage, the cell is quite active at the biochemical level. The cell is accumulating the building blocks of chromosomal DNA and the associated proteins as well as accumulating sufficient energy reserves to complete the task of replicating each chromosome in the nucleus.

S phase (synthesis of dna)

Throughout interphase, nuclear DNA remains in a semi-condensed chromatin configuration. In the S phase    , DNA replication can proceed through the mechanisms that result in the formation of identical pairs of DNA molecules—sister chromatids—that are firmly attached to the centromeric region. The centrosome is duplicated during the S phase. The two centrosomes will give rise to the mitotic spindle    , the apparatus that orchestrates the movement of chromosomes during mitosis. At the center of each animal cell, the centrosomes of animal cells are associated with a pair of rod-like objects, the centrioles , which are at right angles to each other. Centrioles help organize cell division. Centrioles are not present in the centrosomes of other eukaryotic species, such as plants and most fungi.

G 2 Phase (second gap)

In the G 2 phase    , the cell replenishes its energy stores and synthesizes proteins necessary for chromosome manipulation. Some cell organelles are duplicated, and the cytoskeleton is dismantled to provide resources for the mitotic phase. There may be additional cell growth during G 2 . The final preparations for the mitotic phase must be completed before the cell is able to enter the first stage of mitosis.

Questions & Answers

what is element
Kofi Reply
Structure of water molecule and it's biological significance. .....help guys
Ashly
what is the formula for chemical equetion
Justo Reply
Why mitochondria is called the power house of the congo the bahamas cell
Farrukh Reply
how can I learn this subject?
mascuud Reply
what's microscope?
Mathias Reply
A device used to study a very small specimen thst cannt br seen with the naked eyes for example cells, or microorganisms.
Danisha
a medical device used to study cells bacteria viruses and parasites e.g electron microscope for studying cells.
Grace
exactly microscope
Randa
what does multi seminar mean
Grace Reply
how many cells on the human
Amar Reply
how is genetic testing?
Nyabuoy
test
Nyuongatdet
which party of an internal leaf which represent organ and tissue
fernando
3 trilleons cells on the human
Jyoti
name the groups of bacteria, what they cause and explain the components of bacterial cell
Emmanuel
what are the three level of relationship that exist between organism?
Chinedu
who many cell are in the human body
Ayasso Reply
what causes coloring of skin variation
Prince Reply
what is your answer
Jonathan Reply
which qn
Randa
what is chemosynthesis
Irene
who many cell are in the human body
Ayasso
there are billion cells in human body
fazeela
what are three stages of mitosis
jerry
they're alot cells in our body
jerry
what are the stages of mitosis
jerry
they are prophez methaphez anaphez. thelophez
fazeela
anyone to explain each of the following,, prophase, metaphase, anaphase and telophase
jerry
what is a filial
Mbah Reply
what is the difference between chlorophyll and photosynthesis
Rahman Reply
Chloe is the green pigment found in green plants while photosynthesis is the process by which plant produce their own food
mary
photosynthesis is the production of food by plant while chlorophyll is the green pigment that is found in chloroplast..
jerry
chrolophyll (green colouring matter in leaves) while photosynthesis (process by which green plants make their own food)
Nakhombi
What isaac life
Farrukh
what are the functions of parts of microscope
Bami Reply
base to provide support
Ian
only base what about the other
Bami
has only one function
Mark
Mirror ... used to reflect light
Irene
outline 2 ideas of Darwinism theory
Fatma Reply
important of protein in plants
Mark Reply
Protein in plants- repair damaged tissues -
Danisha

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Source:  OpenStax, Biology. OpenStax CNX. Feb 29, 2016 Download for free at http://cnx.org/content/col11448/1.10
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