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Biotechnology in medicine and agriculture

It is easy to see how biotechnology can be used for medicinal purposes. Knowledge of the genetic makeup of our species, the genetic basis of heritable diseases, and the invention of technology to manipulate and fix mutant genes provides methods to treat the disease. Biotechnology in agriculture can enhance resistance to disease, pest, and environmental stress, and improve both crop yield and quality.

Genetic diagnosis and gene therapy

The process of testing for suspected genetic defects before administering treatment is called genetic diagnosis    by genetic testing    . Depending on the inheritance patterns of a disease-causing gene, family members are advised to undergo genetic testing. For example, women diagnosed with breast cancer are usually advised to have a biopsy so that the medical team can determine the genetic basis of cancer development. Treatment plans are based on the findings of genetic tests that determine the type of cancer. If the cancer is caused by inherited gene mutations, other female relatives are also advised to undergo genetic testing and periodic screening for breast cancer. Genetic testing is also offered for fetuses (or embryos with in vitro fertilization) to determine the presence or absence of disease-causing genes in families with specific debilitating diseases.

Gene therapy is a genetic engineering technique used to cure disease. In its simplest form, it involves the introduction of a good gene at a random location in the genome to aid the cure of a disease that is caused by a mutated gene. The good gene is usually introduced into diseased cells as part of a vector transmitted by a virus that can infect the host cell and deliver the foreign DNA ( [link] ). More advanced forms of gene therapy try to correct the mutation at the original site in the genome, such as is the case with treatment of severe combined immunodeficiency (SCID).

To cure disease using an adenovirus vector, a new gene intended to replace a defective one is packaged with the adenovirus genome. The genes that make the virus pathogenic are removed. The modified DNA is put inside the virus’ capsid, or protein coat. The person to be cured is infected with the modified virus. Viral DNA enters the nucleus, where the modified gene can replace the defective one.
Gene therapy using an adenovirus vector can be used to cure certain genetic diseases in which a person has a defective gene. (credit: NIH)

Production of vaccines, antibiotics, and hormones

Traditional vaccination strategies use weakened or inactive forms of microorganisms to mount the initial immune response. Modern techniques use the genes of microorganisms cloned into vectors to mass produce the desired antigen. The antigen is then introduced into the body to stimulate the primary immune response and trigger immune memory. Genes cloned from the influenza virus have been used to combat the constantly changing strains of this virus.

Antibiotics are a biotechnological product. They are naturally produced by microorganisms, such as fungi, to attain an advantage over bacterial populations. Antibiotics are produced on a large scale by cultivating and manipulating fungal cells.

Recombinant DNA technology was used to produce large-scale quantities of human insulin in E. coli as early as 1978. Previously, it was only possible to treat diabetes with pig insulin, which caused allergic reactions in humans because of differences in the gene product. In addition, human growth hormone (HGH) is used to treat growth disorders in children. The HGH gene was cloned from a cDNA library and inserted into E. coli cells by cloning it into a bacterial vector.

Questions & Answers

what is a cell
Reuben Reply
what is an enzymes
Reuben
what is deamination
Mutebi Reply
Is the removal of amino radical from amino acid or any other amino compound.
Esnart
what is metabolism
Allen Reply
metabolism is the the combination of all the reaction that occur within your body
xjuicy_editzz
These reaction can be either anabolic (which is the building up of molecules) or can be catabolism (breaking of molecules) but these processes occur simultaneously to maintain homeostasis(internal body environment) within the body.
xjuicy_editzz
hope that helps :D !!
xjuicy_editzz
list 20 element in their order
Dor Reply
hydrogen helium lithium beryllium boron carbon nitrogen oxygen fluorine neon sodium Magnesium aluminium silicon phosphorus sulfur chlorine Aaron potassium calcium -Also if anyone is having trouble remembering the elements I recommend watching "The Periodic Table of elements song" :)
xjuicy_editzz
anabolic, Because ATP is needed
Avuyileji Reply
?
xjuicy_editzz
definition of biology
LENARD Reply
the branch of science that deals with the study of plants and animals
Emmanuel
alkaloids are excretory product use for
Kekere Reply
What is venation
Mohamed Reply
what is evolution
Anthony Reply
why are you insulting us my niggar?
Emmanuelfray Reply
what is deglutition
Nalumansi Reply
what is biology
Sierrah Reply
biology is a type of science that studies living things
xjuicy_editzz
viruses are composed of what
Daniel Reply
what are some disease caused by virus
Daniel
what are some disease caused by virus
Daniel
what are some disease caused by virus
Daniel
Ebola
Alhassan
Ebola,rabies,polio,hepatitis and small pox
Magoba
Corona (viral disease)
Musoke
viruses kinda in a sense not "living" what mean that a virus molecule that attaches to living organisms cells to destroy/kill them. so to answer your question they are composed/made up of molecules (please note that I am not 100% sure, please feel free to correct me :] )
xjuicy_editzz
what is meiosis
Koosono
what is evolution?
Emmanuelfray
@koosono meiosis is the fusion of gametes (sex cell) to from a zygote and it occurs sexually
xjuicy_editzz
what is the use of biology
Tarkaa Reply
To widen our reasoning abilities about the past and the present events in biology and life at large
Musoke
To understand our biography
Musoke
to study living things
Narh
Among all these which one is the major difference between platyhelminthes and coelenterates? 1. are multicellular 2. have developed a mesoderm 3. reproduce sexually 4. reproduce asexually
Habeeb Reply

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Source:  OpenStax, Biology. OpenStax CNX. Feb 29, 2016 Download for free at http://cnx.org/content/col11448/1.10
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