<< Chapter < Page Chapter >> Page >

Horizontal gene transfer

Horizontal gene transfer (HGT) is the introduction of genetic material from one species to another species by mechanisms other than the vertical transmission from parent(s) to offspring. These transfers allow even distantly related species to share genes, influencing their phenotypes. It is thought that HGT is more prevalent in prokaryotes, but that only about 2% of the prokaryotic genome may be transferred by this process. Some researchers believe such estimates are premature: the actual importance of HGT to evolutionary processes must be viewed as a work in progress. As the phenomenon is investigated more thoroughly, it may be revealed to be more common. Many scientists believe that HGT and mutation appear to be (especially in prokaryotes) a significant source of genetic variation, which is the raw material for the process of natural selection. These transfers may occur between any two species that share an intimate relationship ( [link] ).

Summary of Mechanisms of Prokaryotic and Eukaryotic HGT
Mechanism Mode of Transmission Example
Prokaryotes transformation DNA uptake many prokaryotes
transduction bacteriophage (virus) bacteria
conjugation pilus many prokaryotes
gene transfer agents phage-like particles purple non-sulfur bacteria
Eukaryotes from food organisms unknown aphid
jumping genes transposons rice and millet plants
epiphytes/parasites unknown yew tree fungi
from viral infections

Hgt in prokaryotes

The mechanism of HGT has been shown to be quite common in the prokaryotic domains of Bacteria and Archaea, significantly changing the way their evolution is viewed. The majority of evolutionary models, such as in the Endosymbiont Theory, propose that eukaryotes descended from multiple prokaryotes, which makes HGT all the more important to understanding the phylogenetic relationships of all extant and extinct species.

The fact that genes are transferred among common bacteria is well known to microbiology students. These gene transfers between species are the major mechanism whereby bacteria acquire resistance to antibiotics. Classically, this type of transfer has been thought to occur by three different mechanisms:

  1. Transformation: naked DNA is taken up by a bacteria
  2. Transduction: genes are transferred using a virus
  3. Conjugation: the use a hollow tube called a pilus to transfer genes between organisms

More recently, a fourth mechanism of gene transfer between prokaryotes has been discovered. Small, virus-like particles called gene transfer agents (GTAs) transfer random genomic segments from one species of prokaryote to another. GTAs have been shown to be responsible for genetic changes, sometimes at a very high frequency compared to other evolutionary processes. The first GTA was characterized in 1974 using purple, non-sulfur bacteria. These GTAs, which are thought to be bacteriophages that lost the ability to reproduce on their own, carry random pieces of DNA from one organism to another. The ability of GTAs to act with high frequency has been demonstrated in controlled studies using marine bacteria. Gene transfer events in marine prokaryotes, either by GTAs or by viruses, have been estimated to be as high as 10 13 per year in the Mediterranean Sea alone. GTAs and viruses are thought to be efficient HGT vehicles with a major impact on prokaryotic evolution.

Questions & Answers

what is a specicide
Twinkl Reply
why are mosquitoes primary and secondary consumers
Twinkl
what are the structures found in all viruses
Twinkl
how does vaccinating a woman prevent her baby from getting the illness?
Twinkl
how does selective breeding increase crop size
Twinkl
wat is an animal cell
Monicah Reply
what is deer
Khansawu Reply
breathing in reptiles
sam Reply
which molecules binds to the active site of an enzyme
Ghulam Reply
human
Haggai
what is nutrients
Patrick Reply
nutrients is substance which body use in terms of need
Haggai
yes..
Abdullahi
can I join?
Osei
substance that provides nourishment essential for the maintenance of life and for growth.
umar
right same answer as you Umar
Namuli
please remind me
Namuli
Any material that provide essential components for cell metabolisms is nutrient
Mahmood
what are the types of skeleton
Tanyi Reply
endo skeleton and exo skeleton
Faith
or types of skeletons There is exo skeleton found in class insecta Exo skeleton found in phylum chordata and lastly hydrostatic skeleton found mainly in earth worms
Daniel
and hydrostatic skeleton
Godbless
bronah
Kapoko
endo, exo and hydrostatic skeleton
Mico
what is life?
Jerson Reply
life is when any living thing breath or respirate.
Lucky
I want to join
Patrick
me too
Favour
me two
Monday
me too
Bengazy
me too
Maggie
I here
Yahaya
Does anybody knows another biology app that brings good understand
Lucky
give an example of a phylum where all members have open circulatory
Omoro Reply
anthropoda
Daniel
phylum Anthropoda
Daniel
how do u change the unit of temperature from degree celsius to degree Fahrenheit
Maggie
what are beneficial effects in industrial
Nnamani Reply
create employment
ibrahim
provide food
ibrahim
pollution
ibrahim
dirty the environment
ibrahim
pollution and lack of knowledge about how to manage waste
Alex
what is gametophyte
Ibrahim Reply
what is biology
Basiru Reply
Biology deals with the study of living organisms and their interactions with each other and the environment.
Quartey
biology simply means the study of living and non-livingthings.
Shamstar
what is the meaning of ubiquitous
Hamziyatu Reply
Under what topic is this question
fred
three branches of biology
Alexander Reply
what is the cell
Olajide Reply
what is life
Olajide
cell is the functional and structural unit of life
Shweta
life is a problem solving entity
Atanga
what is the characteristics of plant cell
Quaku

Get the best Biology course in your pocket!





Source:  OpenStax, Biology. OpenStax CNX. Feb 29, 2016 Download for free at http://cnx.org/content/col11448/1.10
Google Play and the Google Play logo are trademarks of Google Inc.

Notification Switch

Would you like to follow the 'Biology' conversation and receive update notifications?

Ask