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The morphology of white blood cells differs significantly from red blood cells. They have nuclei and do not contain hemoglobin. The different types of white blood cells are identified by their microscopic appearance after histologic staining, and each has a different specialized function. The two main groups, both illustrated in [link] are the granulocytes, which include the neutrophils, eosinophils, and basophils, and the agranulocytes, which include the monocytes and lymphocytes.

Illustration A shows the granulocytes, which include neutrophils, eosinophils, and basophils. The three cell types are similar in size, with lobed nuclei and granules in the cytoplasm. Illustration B shows agranulocytes, including lymphocytes and monocytes. The monocyte is somewhat larger than the lymphocyte and has a U-shaped nucleus. The lymphocyte has an oblong nucleus.
(a) Granulocytes—including neutrophils, eosinophils and basophils—are characterized by a lobed nucleus and granular inclusions in the cytoplasm. Granulocytes are typically first-responders during injury or infection. (b) Agranulocytes include lymphocytes and monocytes. Lymphocytes, including B and T cells, are responsible for adaptive immune response. Monocytes differentiate into macrophages and dendritic cells, which in turn respond to infection or injury.

Granulocytes contain granules in their cytoplasm; the agranulocytes are so named because of the lack of granules in their cytoplasm. Some leukocytes become macrophages that either stay at the same site or move through the blood stream and gather at sites of infection or inflammation where they are attracted by chemical signals from foreign particles and damaged cells. Lymphocytes are the primary cells of the immune system and include B cells, T cells, and natural killer cells. B cells destroy bacteria and inactivate their toxins. They also produce antibodies. T cells attack viruses, fungi, some bacteria, transplanted cells, and cancer cells. T cells attack viruses by releasing toxins that kill the viruses. Natural killer cells attack a variety of infectious microbes and certain tumor cells.

One reason that HIV poses significant management challenges is because the virus directly targets T cells by gaining entry through a receptor. Once inside the cell, HIV then multiplies using the T cell’s own genetic machinery. After the HIV virus replicates, it is transmitted directly from the infected T cell to macrophages. The presence of HIV can remain unrecognized for an extensive period of time before full disease symptoms develop.

Platelets and coagulation factors

Blood must clot to heal wounds and prevent excess blood loss. Small cell fragments called platelets (thrombocytes) are attracted to the wound site where they adhere by extending many projections and releasing their contents. These contents activate other platelets and also interact with other coagulation factors, which convert fibrinogen, a water-soluble protein present in blood serum into fibrin (a non-water soluble protein), causing the blood to clot. Many of the clotting factors require vitamin K to work, and vitamin K deficiency can lead to problems with blood clotting. Many platelets converge and stick together at the wound site forming a platelet plug (also called a fibrin clot), as illustrated in [link] b . The plug or clot lasts for a number of days and stops the loss of blood. Platelets are formed from the disintegration of larger cells called megakaryocytes, like that shown in [link] a . For each megakaryocyte, 2000–3000 platelets are formed with 150,000 to 400,000 platelets present in each cubic millimeter of blood. Each platelet is disc shaped and 2–4 μm in diameter. They contain many small vesicles but do not contain a nucleus.

Questions & Answers

this is a specialized part of the cell eg Nucleus
David Reply
what are the organelles?
Faith Reply
what is reproduction
mana Reply
reproduction is the process by which living organisms give rise to young ones of their own kind
What is evolution
the production of new forms of life over time as documented in the fossil record.
give two parasites where secondary host is water snail?
Kevin Reply
what is treats
Raih Reply
what are the organelles in cell that involves in protein sythenis
Rita Reply
what is a melanin?
Judith Reply
what is telophase
melanin in that black color we posse in our skins
Why do parasites take on a parasitic life?
Asadullah Reply
what is cell
Ousman Reply
A cell is the basic structure unit of an organ
what is respiration
what is organisms?
Organisms are living things that can function on their own
A cell is a functional basic unit of an organisms.
Organisms is a entity which consists of one or more cells and are able to undergo all life processes
A respiration is the physical and chemical break down of complex food substance into absorbable or simple form.
What will to a cell if the nucleus is removed..?
Goodrick Reply
When a cell nucleus removed then the cell will not be able to function properly, it will not be able to grow .All the metabolic functioning of the cell will stop .Without nucleus the cell will lose it's control. It can not carry out cellular reproduction .
defin peroxesome
write a short note on how the kidney carry out osmoregulation in man
Rhoda Reply
Kidney play a very large role in human osoregulation by regulating the amount of water reabsorbed from glomerular filtrate in kidney as tubules, which is controlled by hormones such as antrdiuvetic hormone (ADH) , aldosterone and angiotensin.
kidney is capable of osmoregulation in mammal ,
simple definition for respiratory system
Gift Reply
Respiratory system is a network of organs and tissues that helps you to breathe or help in getting the rids of oxygen and discharge of carbon dioxide in the body.
What are uses of respiratory system
how it functions
what is inresparetion
Why do parasites take on a parasitic life?
A respiratory system is a biological system consisting of specific organs and structures used for gas exchange in animals and plant
diseases of respiration
when air enters to the body called inresparetion
explain why plants responds to stimuli slowly than animals
how is a aerenchyma tissue adapted to its function
fatuma Reply
Have large air spaces that store air for gaseous exchange... Large air spaces also facilitate bouyancy.
what does DNA mean
innocent Reply
dioxiribo nucleic acid
Deoxyribonucleic acid
dioxide nucleic acid
what does RNA mean
Ribonucleic acid
what is DNA and RNA
defin work of DNA
it's control gene expression during the cell cycle
what is a zygote
Victor Reply
zygote is developed or fertilized egg cell

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Source:  OpenStax, Biology. OpenStax CNX. Feb 29, 2016 Download for free at http://cnx.org/content/col11448/1.10
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