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Part a shows a micrograph of the varicella-zoster virus, which has an icosahedral capsid surrounded by an irregularly shaped envelope. Part b shows a red, bumpy shingles rash on a person’s face.
(a) Varicella-zoster, the virus that causes chickenpox, has an enveloped icosahedral capsid visible in this transmission electron micrograph. Its double-stranded DNA genome becomes incorporated in the host DNA and can reactivate after latency in the form of (b) shingles, often exhibiting a rash. (credit a: modification of work by Dr. Erskine Palmer, B. G. Martin, CDC; credit b: modification of work by “rosmary”/Flickr; scale-bar data from Matt Russell)

Some animal-infecting viruses, including the hepatitis C virus discussed above, are known as oncogenic viruses : They have the ability to cause cancer. These viruses interfere with the normal regulation of the host cell cycle either by either introducing genes that stimulate unregulated cell growth (oncogenes) or by interfering with the expression of genes that inhibit cell growth. Oncogenic viruses can be either DNA or RNA viruses. Cancers known to be associated with viral infections include cervical cancer caused by human papillomavirus (HPV) ( [link] ), liver cancer caused by hepatitis B virus, T-cell leukemia, and several types of lymphoma.

The micrograph shows an icosahedral virus with glycoproteins protruding from its capsid.
HPV, or human papillomavirus, has a naked icosahedral capsid visible in this transmission electron micrograph and a double-stranded DNA genome that is incorporated into the host DNA. The virus, which is sexually transmitted, is oncogenic and can lead to cervical cancer. (credit: modification of work by NCI, NIH; scale-bar data from Matt Russell)

Visit the interactive animations showing the various stages of the replicative cycles of animal viruses and click on the flash animation links.

Plant viruses

Plant viruses, like other viruses, contain a core of either DNA or RNA. You have already learned about one of these, the tobacco mosaic virus. As plant viruses have a cell wall to protect their cells, these viruses do not use receptor-mediated endocytosis to enter host cells as is seen with animal viruses. For many plant viruses to be transferred from plant to plant, damage to some of the plants’ cells must occur to allow the virus to enter a new host. This damage is often caused by weather, insects, animals, fire, or human activities like farming or landscaping. Additionally, plant offspring may inherit viral diseases from parent plants. Plant viruses can be transmitted by a variety of vectors, through contact with an infected plant’s sap, by living organisms such as insects and nematodes, and through pollen. When plants viruses are transferred between different plants, this is known as horizontal transmission    , and when they are inherited from a parent, this is called vertical transmission    .

Symptoms of viral diseases vary according to the virus and its host ( [link] ). One common symptom is hyperplasia    , the abnormal proliferation of cells that causes the appearance of plant tumors known as galls . Other viruses induce hypoplasia    , or decreased cell growth, in the leaves of plants, causing thin, yellow areas to appear. Still other viruses affect the plant by directly killing plant cells, a process known as cell necrosis    . Other symptoms of plant viruses include malformed leaves, black streaks on the stems of the plants, altered growth of stems, leaves, or fruits, and ring spots, which are circular or linear areas of discoloration found in a leaf.

Some Common Symptoms of Plant Viral Diseases
Symptom Appears as
Hyperplasia Galls (tumors)
Hypoplasia Thinned, yellow splotches on leaves
Cell necrosis Dead, blackened stems, leaves, or fruit
Abnormal growth patterns Malformed stems, leaves, or fruit
Discoloration Yellow, red, or black lines, or rings in stems, leaves, or fruit

Plant viruses can seriously disrupt crop growth and development, significantly affecting our food supply. They are responsible for poor crop quality and quantity globally, and can bring about huge economic losses annually. Others viruses may damage plants used in landscaping. Some viruses that infect agricultural food plants include the name of the plant they infect, such as tomato spotted wilt virus, bean common mosaic virus, and cucumber mosaic virus. In plants used for landscaping, two of the most common viruses are peony ring spot and rose mosaic virus. There are far too many plant viruses to discuss each in detail, but symptoms of bean common mosaic virus result in lowered bean production and stunted, unproductive plants. In the ornamental rose, the rose mosaic disease causes wavy yellow lines and colored splotches on the leaves of the plant.

Section summary

Viral replication within a living cell always produces changes in the cell, sometimes resulting in cell death and sometimes slowly killing the infected cells. There are six basic stages in the virus replication cycle: attachment, penetration, uncoating, replication, assembly, and release. A viral infection may be productive, resulting in new virions, or nonproductive, which means that the virus remains inside the cell without producing new virions. Bacteriophages are viruses that infect bacteria. They have two different modes of replication: the lytic cycle, where the virus replicates and bursts out of the bacteria, and the lysogenic cycle, which involves the incorporation of the viral genome into the bacterial host genome. Animal viruses cause a variety of infections, with some causing chronic symptoms (hepatitis C), some intermittent symptoms (latent viruses such a herpes simplex virus 1), and others that cause very few symptoms, if any (human herpesviruses 6 and 7). Oncogenic viruses in animals have the ability to cause cancer by interfering with the regulation of the host cell cycle. Viruses of plants are responsible for significant economic damage in both agriculture and plants used for ornamentation.

Art connections

[link] Influenza virus is packaged in a viral envelope that fuses with the plasma membrane. This way, the virus can exit the host cell without killing it. What advantage does the virus gain by keeping the host cell alive?

[link] The host cell can continue to make new virus particles.

Got questions? Get instant answers now!

[link] Which of the following statements is false?

  1. In the lytic cycle, new phage are produced and released into the environment.
  2. In the lysogenic cycle, phage DNA is incorporated into the host genome.
  3. An environmental stressor can cause the phage to initiate the lysogenic cycle.
  4. Cell lysis only occurs in the lytic cycle.

[link] C

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Questions & Answers

what is the function of a nucleus
Japheth Reply
The different between animal cells and plant cells
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explain pyramids of numbers
Saanui Reply
a structure of the nerve cell
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amofa Reply
12
angelina
we Ave 21 families rna and dna viruses
Opeyemi
14 virus
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Zanga Reply
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Heidi
state the factors that determine energy requirements in human body?
Samson Reply
Name and explain 2 nutrients that do not require digestion before they are absorbed
Samson
Name and explain 2 nutrients that do not require digestion before they are absorbed
Samson
Name and explain 2 nutrients that do not require digestion before they are absorbed
Samson
Name and explain 2 nutrients that do not require digestion before they are absorbed
Samson
Name and explain 2 nutrients that do not require digestion before they are absorbed
Samson
Name and explain 2 nutrients that do not require digestion before they are absorbed
Samson
Name and explain 2 nutrients that do not require digestion before they are absorbed
Samson
water : it's a nutrient which helps in d proper digestion of nutrients, it doesn't require digestion because it's not affected by any factor in d mouth, and digestion start from the buccal cavity.
aweda
What are the relationship between Biology and Agriculture
Chisco Reply
what are the relationship between biology and chemistry
Abel
Hooliganism the study of living things(plants and animals) and chemistry focuses on chemical composition of matter.😊
Ronke
biology is the study of all life whereas agriculture is the science of cultivating the land including harvesting of crops, rearing and management of animals and tillage
angelina
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Elizabeth
biology is the study of livingthing and non livingthing
Fahamia
boilogy is the study of life whilst agriculture is the study of crops etc...
Amoah
which cell organelle is found in abundance in skeletal tissue
Samson Reply
What are the functions of the cell membrane?
Samson Reply
Detects self cells and foreign cells during invasion by pathogens in the cell Protects the cell content Makes the cell very flexible in its function To regulate the entry n exit of substances in and out of the cell(selective permeability)
Agyei
controls the movement of substance in and out of the cell
Queen
cell membrane control movement in the cell
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what is the four chambers of the human heart and their functions.
Ismile Reply
right and left auricles right and left ventricles
Faith
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Stuart Reply
2
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Samuel
We are dealing with biology
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Odinaka Reply
I want to know if the following stated is be 1.increase, 2. decrease, 3. steady. 1. blood pressure 2. Blood volume 3. ECF volume 4. ICF volume 5. HCT volume 6. Blood protein concentration 7. ECF protein concentration 8. ICF protein concentration 9. Oxygen supply to the brain cells
Rinda Reply
increase
Favour
What are the types of cells?
Akuoch-magol
the two main type of cells are prokaryotic cell and eukaryotic cell but there are also other cells in the human body such as:the nerve cell,skin cell ,blood cell,bone cell etc
angelina
eukaryote cell prokaryotic cell erkayortic cell
Elizabeth
what is the word phylogeny means?
Bae Reply
what is the word biology means?
bio-study logos(logy)- life so biology means the study of life
okonkwo
Please what's the meaning of deductive reasoning
Godfred
the evolutionary history of a kind of organisms
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Source:  OpenStax, Biology. OpenStax CNX. Feb 29, 2016 Download for free at http://cnx.org/content/col11448/1.10
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