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By the end of this section, you will be able to:
  • Explain how hormones regulate the excretory system
  • Discuss the role of hormones in the reproductive system
  • Describe how hormones regulate metabolism
  • Explain the role of hormones in different diseases

Hormones have a wide range of effects and modulate many different body processes. The key regulatory processes that will be examined here are those affecting the excretory system, the reproductive system, metabolism, blood calcium concentrations, growth, and the stress response.

Hormonal regulation of the excretory system

Maintaining a proper water balance in the body is important to avoid dehydration or over-hydration (hyponatremia). The water concentration of the body is monitored by osmoreceptors in the hypothalamus, which detect the concentration of electrolytes in the extracellular fluid. The concentration of electrolytes in the blood rises when there is water loss caused by excessive perspiration, inadequate water intake, or low blood volume due to blood loss. An increase in blood electrolyte levels results in a neuronal signal being sent from the osmoreceptors in hypothalamic nuclei. The pituitary gland has two components: anterior and posterior. The anterior pituitary is composed of glandular cells that secrete protein hormones. The posterior pituitary is an extension of the hypothalamus. It is composed largely of neurons that are continuous with the hypothalamus.

The hypothalamus produces a polypeptide hormone known as antidiuretic hormone (ADH)    , which is transported to and released from the posterior pituitary gland. The principal action of ADH is to regulate the amount of water excreted by the kidneys. As ADH (which is also known as vasopressin) causes direct water reabsorption from the kidney tubules, salts and wastes are concentrated in what will eventually be excreted as urine. The hypothalamus controls the mechanisms of ADH secretion, either by regulating blood volume or the concentration of water in the blood. Dehydration or physiological stress can cause an increase of osmolarity above 300 mOsm/L, which in turn, raises ADH secretion and water will be retained, causing an increase in blood pressure. ADH travels in the bloodstream to the kidneys. Once at the kidneys, ADH changes the kidneys to become more permeable to water by temporarily inserting water channels, aquaporins, into the kidney tubules. Water moves out of the kidney tubules through the aquaporins, reducing urine volume. The water is reabsorbed into the capillaries lowering blood osmolarity back toward normal. As blood osmolarity decreases, a negative feedback mechanism reduces osmoreceptor activity in the hypothalamus, and ADH secretion is reduced. ADH release can be reduced by certain substances, including alcohol, which can cause increased urine production and dehydration.

Chronic underproduction of ADH or a mutation in the ADH receptor results in diabetes insipidus    . If the posterior pituitary does not release enough ADH, water cannot be retained by the kidneys and is lost as urine. This causes increased thirst, but water taken in is lost again and must be continually consumed. If the condition is not severe, dehydration may not occur, but severe cases can lead to electrolyte imbalances due to dehydration.

Questions & Answers

why drinking excess alcohol causes thirst and dehydration
uwikuzo Reply
what is reproduction
smart Reply
it is d act of bringing young ones to life
Oyebanji
to ensure survival of a species🚴‍♀️
Michelle
what is a genotype
Collins
what is hazardous
smart
a cell is the smallest unit of a living thing. so we all have cell
smart
It is the formation of a zygote resulting from the fusion of the sperm cell with the ovum.Thus,this results in the production of new species which are genetically dissimilar from their parent cells.
Pallavi
what is size of cell
Mohd Reply
what is size of Hart
Mohd
nanometers=um sign thingie
Michelle
microns=nanometers
Michelle
monomers and polymers of nucleic acids?
Jyrl Reply
dna and rna involvement
Michelle
give me the elements of the soil
Iguma Reply
Air, water, organic matter, inorganic matter
Tshwano
soil water humus air
Veronicah
yap
Beloved
silica, iron
Patience
potassium, sulfur, calcium, carbon
Michelle
what is cell
iyaji Reply
A cell is a smallest fundamental unit of a living organisms.
Kem
the basic structural and functional unit of life
Patience
what is size of cell
Mohd
all things are made up of.....all things cannot exist without pre-exisiting cells...check out the 16th ce tury to learn more about microscope use and cells. i will give a hint: Mr. L.
Michelle
we are all made of cells
Michelle
Nutrition - sensitive intervention
Therowda Reply
what does the sori In fern mean
arhin Reply
biology is the study .exactly what is life?
Jerry
i'm sorry , the study of life
Jerry
how can U identify a person through his blood
Frankyx Reply
through genetic fingerprinting where specific DNA sequences in a person genome can be identified.
Pallavi
by help of genetics and DNA test
Meerbadini
can it also be detected using an RNA test
Frankyx
environmental biology
Ojesola Reply
what is phytoplankton
Ojesola
What is anabolism
Treasure Reply
the break down of substance
Aunty
how many teeth has an adult person
TSEGAY Reply
36
Treasure
32
Favour
32
Kamaluddeen
32 teeth
Meerbadini
32
OLAMIDE
32 (or 36 including the wisdom teeth)
Hailey
32
Sani
26?🤓
Michelle
what is homoestastis
Ayo Reply
hypothalamus negative feedback vs. postive feedback systems.
Michelle
it is the maintenance of a steady internal environment.it is controlled largely by the brain especially the hypothalamus.
Oyebanji
What is a cell
Eric Reply
A cell is the building block of all organisms
Millicent
yes it is , it also helps in functions .
Joezman
cell is structural & functional unit of oraganisms
Meerbadini
it is a building blocks of a living organism
Joezman
it is the basic unit of life in living organisms
Nabwonso
it is the basic unite of life in living organisms
Nabwonso
it is the fundamental unit of life
Adewoye
it is the structural and functional unit of life
Ojesola
Why cells are classify as living and non living things
Millicent Reply
due to such as virus which acts as a living cell inside the cell of an organisms and out side of cell in form of crystals
Meerbadini
because there are living cells which performs complex processes such as reproduction and metabolism then there are dead cells like the top most part of the epidermis or the bark
irish
because there are living cells which performs complex function such as reproduction and metabolism
David
cause otherwise you could call fire alive
Marissa

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Source:  OpenStax, Biology. OpenStax CNX. Feb 29, 2016 Download for free at http://cnx.org/content/col11448/1.10
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