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Dynamic, learner-centered art

Our unique approach to visuals is designed to emphasize only the components most important in any given illustration. The art style is particularly aimed at focusing student learning through a powerful blend of traditional depictions and instructional innovations.

Much of the art in this book consists of black line illustrations. The strongest line is used to highlight the most important structures, and shading is used to show dimension and shape. Color is used sparingly to highlight and clarify the primary anatomical or functional point of the illustration. This technique is intended to draw students’ attention to the critical learning point in the illustration, without distraction from excessive gradients, shadows, and highlights. Full color is used when the structure or process requires it (for example, muscle diagrams and cardiovascular system illustrations).

The pharynx

A color illustration of the pharynx.
By highlighting the most important portions of the illustration, the artwork helps students focus on the most important points, without overwhelming them.


Micrograph magnifications have been calculated based on the objective provided with the image. If a micrograph was recorded at 40×, and the image was magnified an additional 2×, we calculated the final magnification of the micrograph to be 80×.

Please note that, when viewing the textbook electronically, the micrograph magnification provided in the text does not take into account the size and magnification of the screen on your electronic device. There may be some variation.

Sebaceous glands

A color illustration of the pharynx.
These glands secrete oils that lubricate and protect the skin. LM × 400. (Micrograph provided by the Regents of University of Michigan Medical School © 2012)

Learning resources

The following resources are (or will be) available in addition to main text:

  • PowerPoint slides: For each chapter, the illustrations are presented, one per slide, with their respective captions.
  • Pronunciation guide: A subset of the text’s key terms are presented with easy-to-follow phonetic transcriptions. For example, blastocyst is rendered as “blas'to-sist”

About our team

Senior contributing authors

J. Gordon Betts Tyler Junior College
Peter Desaix University of North Carolina at Chapel Hill
Eddie Johnson Central Oregon Community College
Jody E. Johnson Arapahoe Community College
Oksana Korol Aims Community College
Dean Kruse Portland Community College
Brandon Poe Springfield Technical Community College
James A. Wise Hampton University
Mark Womble Youngstown State University
Kelly A. Young California State University, Long Beach


Robin J. Heyden

Contributing authors

Kim Aaronson Aquarius Institute; Triton College
Lopamudra Agarwal Augusta Technical College
Gary Allen Dalhousie University
Robert Allison McLennan Community College
Heather Armbruster Southern Union State Community College
Timothy Ballard University of North Carolina Wilmington
Matthew Barlow Eastern New Mexico University
William Blaker Furman University
Julie Bowers East Tennessee State University
Emily Bradshaw Florida Southern College
Nishi Bryska University of North Carolina, Charlotte
Susan Caley Opsal Illinois Valley Community College
Boyd Campbell Southwest College of Naturopathic Medicine and Health Sciences
Ann Caplea Walsh University
Marnie Chapman University of Alaska, Sitka
Barbara Christie-Pope Cornell College
Kenneth Crane Texarkana College
Maurice Culver Florida State College at Jacksonville
Heather Cushman Tacoma Community College
Noelle Cutter Molloy College
Lynnette Danzl-Tauer Rock Valley College
Jane Davis Aurora University
AnnMarie DelliPizzi Dominican College
Susan Dentel Washtenaw Community College
Pamela Dobbins Shelton State Community College
Patty Dolan Pacific Lutheran University
Sondra Dubowsky McLennan Community College
Peter Dukehart Three Rivers Community College
Ellen DuPré Central College
Elizabeth DuPriest Warner Pacific College
Pam Elf University of Minnesota
Sharon Ellerton Queensborough Community College
Carla Endres Utah State University - College of Eastern Utah: San Juan Campus
Myriam Feldman Lake Washington Institute of Technology; Cascadia Community College
Greg Fitch Avila University
Lynn Gargan Tarant County College
Michael Giangrande Oakland Community College
Chaya Gopalan St. Louis College of Pharmacy
Victor Greco Chattahoochee Technical College
Susanna Heinze Skagit Valley College
Ann Henninger Wartburg College
Dale Horeth Tidewater Community College
Michael Hortsch University of Michigan
Rosemary Hubbard Marymount University
Mark Hubley Prince George's Community College
Branko Jablanovic College of Lake County
Norman Johnson University of Massachusetts Amherst
Mark Jonasson North Arkansas College
Jeff Keyte College of Saint Mary
William Kleinelp Middlesex County College
Leigh Kleinert Grand Rapids Community College
Brenda Leady University of Toledo
John Lepri University of North Carolina, Greensboro
Sarah Leupen University of Maryland, Baltimore County
Lihua Liang Johns Hopkins University
Robert Mallet University of North Texas Health Science Center
Bruce Maring Daytona State College
Elisabeth Martin College of Lake County
Natalie Maxwell Carl Albert State College, Sallisaw
Julie May William Carey University
Debra McLaughlin University of Maryland University College
Nicholas Mitchell St. Bonaventure University
Shobhana Natarajan Brookhaven College
Phillip Nicotera St. Petersburg College
Mary Jane Niles University of San Francisco
Ikemefuna Nwosu Parkland College; Lake Land College
Betsy Ott Tyler Junior College
Ivan Paul John Wood Community College
Aaron Payette College of Southern Nevada
Scott Payne Kentucky Wesleyan College
Cameron Perkins South Georgia College
David Pfeiffer University of Alaska, Anchorage
Thomas Pilat Illinois Central College
Eileen Preston Tarrant County College
Mike Pyle Olivet Nazarene University
Robert Rawding Gannon University
Jason Schreer State University of New York at Potsdam
Laird Sheldahl Mt. Hood Community College
Brian Shmaefsky Lone Star College System
Douglas Sizemore Bevill State Community College
Susan Spencer Mount Hood Community College
Cynthia Standley University of Arizona
Robert Sullivan Marist College
Eric Sun Middle Georgia State College
Tom Swenson Ithaca College
Kathleen Tallman Azusa Pacific University
Rohinton Tarapore University of Pennsylvania
Elizabeth Tattersall Western Nevada College
Mark Thomas University of Northern Colorado
Janis Thompson Lorain County Community College
Rita Thrasher Pensacola State College
David Van Wylen St. Olaf College
Lynn Wandrey Mott Community College
Margaret Weck St. Louis College of Pharmacy
Kathleen Weiss George Fox University
Neil Westergaard Williston State College
David Wortham West Georgia Technical College
Umesh Yadav University of Texas Medical Branch
Tony Yates Oklahoma Baptist University
Justin York Glendale Community College
Cheri Zao North Idaho College
Elena Zoubina Bridgewater State University; Massasoit Community College
Shobhana Natarajan Alcon Laboratories, Inc.

Special thanks

OpenStax wishes to thank the Regents of University of Michigan Medical School for the use of their extensive micrograph collection. Many of the UM micrographs that appear in Anatomy and Physiology are interactive WebScopes, which students can explore by zooming in and out.

We also wish to thank the Open Learning Initiative at Carnegie Mellon University, with whom we shared and exchanged resources during the development of Anatomy and Physiology .

Questions & Answers

how to identify tissues cells under a microscope
Carla Reply
any advice on how to identify tissue cells under a microscope?
What is homeostasis
Haji Reply
ability of living organisms to adjust it internal environment to maintain a stable equilibrium
how to identify tissues cells under a microscope
what is the anatomy
aamina Reply
anatomy is the branch of science concerned with the bodily structure of humans animals and other living organisms, especially as revealed by dissection and the separation of parts.
what are silhouettes
Magret Reply
is dis Medical term?
but I don't know what it means
silhouette outline of a figure. The sharpness of the silhouette is a function of the shape, size and density of the object. This is most marked in radiography. basketball-shaped silhouette the enlarged cardiac outline seen in the dorsal-ventral view of the thorax in a dog with chronic pericardial
it's the first stage of wound healing that involves vasoconstriction platelet plug formation and blood clotting
Levels of complexity
sorry that was fast hemostasis
Anti there is homeostasis and haemostasis
yes , homeostasis is the abiltity of a living organism to adjust it environment to maintain a stable equilibrium
Thank you Alice, how about Haemostasis?
why are postsynaptic ganglionic neurons unmyelinated
Callie Reply
Postganglionic motor neurons are unmyelinated because the lack myelin sheath. The myelin sheath on the peripheral nervous system is composed of Schwann cells wrapped around the axon inside the endoneurium.
they lack*
Postganglionic (and preganglionic) motor neurons belong to the division of the autonomic nervous system. In contrast, the somatic nervous system contains only one long thick myelinated somatic presynaptic motor neuron.
anatomy defination in urdu
Atif Reply
human body largest organ.....
jasveer Reply
liver and skin
by mass is liver but externally is de skin
all answers Are correct
liver is the largest gland of the body but skin is the largest organ of the body
so please what is the answer now
afcous skin.because difference between Gland and organ
Only the skin
The largest organ is the skin and the liver is a gland
skin is the largest organ of the body
it's the skin
skin 100%
largest organ- liver largest system- Skin
largest organ is skin because it covers the rest of the organs
liver right answers
liver is largest gland
skin is largest organ liver is largest gland femur is largest bone thyroid gland is largest endocrine gland seratus muscle is largest muscle
sciatic nerve is largest nerve
portal vein is largest vein
GIT is largest tube in body
explain about cerebrum cereblum and pons medulla
Nervous system anotomy and physiology
skin is the human body's largest organ
@Tanveer, the cerebrum consists of the cerebral cortex, corpus callosum, hippocampus, and basal ganglia. The cerebellum is located inferior to the occipital lobe. The pons and medulla are part of the lower brainstem.
The cerebral cortex are divided into 4 lobes and control functions such as: thinking, learning, speech, sensory perception, motor functions, hearing and vision, etc. The cerebral cortex is mainly present only in mammals due to evolution. The hippocampus plays a main role in memory formation.
The cerebellum works together with the motor cortex and other parts of the brain to coordinate and fine tune muscular activity. The pons and medulla control autonomic functions such as: sleep, respiration, swallowing, vomiting, heart rate, vasomotor control and more other things.
skin hai friend
what is the biliary tract
The biliary tract involves the liver, gallbladder, and bile duct. Certain liver cells (hepatocytes) synthesize bile salts derived from cholesterol in response to Secretin hormone. The gallbladder stores the bile. Gallbladder releases bile to the bile duct in response to Cholecystokinin hormone.
The role of bile is to emulsify fats so that they can be easily broken down and absorbed by the enterocytes into the lacteal vessels.
what is the difference between negative feedback loop and positive feedback loop
what is cholesterol
unsaturated fats
so what is the main purpose of anomaly
Cholesterol is a waxy substance your body uses to protect nerves, make cell tissues, and produce certain hormones.
Cholesterol is a type of lipid and it is a nonpolar molecule. The molecule is mainly composed of hydrocarbon chains. Cholesterol is synthesized in the smooth endoplasmic reticulum in eukaryotic cells, and is the main building block material for steroids, Vit D, and bile salts.
Negative feedback loop reverses any change back to its set point. For ex, when your internal body temperature rises above 98.6 F, your hypothalamus triggers your dermal blood vessels to dilate and activate sweat glands through sympathetic motor nerves so you can sweat and cool off back to 98.6 F.
Positive feedback loop amplifies a change. For ex, during labor, oxytocin is released continuously in a positive feedback loop from the posterior pituitary gland to stimulate contraction of the myometrium so the baby can come out.
define homeostasis and explain it's importants
Adusei Reply
define the important life processes of humans
how the bone marrow transplantation is done?
what is homeostasis
julie Reply
internal temperature of body
Homeostasis is the internal constancy in which your body tries to maintain for optimal cellular functioning. For example, your body tries to maintain an internal body temperature of about 98.6F for optimal functioning of your body.
If a prolonged lost of homeostasis occurs, death of the organism will be the outcome.
Another example of homeostasis is that your body tries to maintain a specific blood sugar level, so that your cells can undergo constant cellular respiration and keep you alive.
homeostasis is the fairly constant internal changes of an environment (your internal environment).The temperature of a body must be kept between the range of 37.5°c
which tissue is more sensitive
Rit Reply
to what?
myasthenia gravis?
Myasthenia gravis is an autoimmune disease in which your own antibodies (produced by plasma cells) attack and inhibit nicotinic receptors at the neuromuscular junction.
As a result, acetylcholine will not bind to nicotinic receptors and now action potential is produced on the sarcolema. If no AP is produce, then there is no contraction of the muscle. For a long period of time, this will result in atrophy and muscle weakness.
and no action potential*
explain types of hypertension
Juli Reply
What is bulbar paralysis?
Roshni Reply
how can make penis larger
Marwat Reply
what is the stimuli initiates the control of erythropoiesis?
Ok Reply
Erythropoietin, a hormone synthesized and released by the kidneys stimulate erythropoiesis in red bone marrow. When an Individual loses blood (hemorrhage) and the concentration of RBCs or oxygen decreases, erythropoitein will be released.
how lymph is from
Hafsa Reply
Lymph is essentially interstitial fluid that ends up in the lymphatic vessels that didn't go back into the venules. Lymph is composed of the same components as your blood plasma which contains water, solutes, oxygen, CO2, foreign particles such as toxins, bacteria and viruses.
what is the cause of twins
The cause of identical twins is when a single fertilized egg undergo mitosis (splits in two) . As a result, both eggs now have the same genetic information, therefore producing two identical twins.
Different twins (fraternal) occurs when two different eggs are ovulated and two different sperm fertilize each egg. As a result, fraternal twins are not genetically identical and can even be opposite sex.
Fraternal twins occurs when two different eggs are ovulated and two different sperm fertilize each egg. As a result, fraternal twins are not genetically identical and can even be opposite sex.
If two eggs are ovulated during ovulation, and two different sperms fertilize each egg then fraternal twins will occur. Fraternal twins are not generically identical and can even be opposite sex.
Fraternal twins occurs when two different eggs are ovulated and two different sperm fertilize each egg. As a result, fraternal twins are not genetically identical and can even be opposite sex.
how structure and function relate to each other?
This is a very important rule in Anatomy and Physiology. The structure of a cell, tissue, or organ will tell you a lot about it's function.
For example, simple columnar cells (enterocytes) in the villus present in the duodenum of the small intestine contain microvilli. Microvilli are finger like projections of the cell membrane (produce by the cytoskeleton)that increase the surface area for absorption of nutrients into the enterocytes.
The main role of these enterocytes is to absorb. Therefore, having Microvilli as a structure relates to its function.
@ Carmelo thanks for the answer.
what is the difference between negative feedback loop and positive feedback loop

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Source:  OpenStax, Anatomy & Physiology. OpenStax CNX. Feb 04, 2016 Download for free at http://legacy.cnx.org/content/col11496/1.8
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