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B cells

B cells    are immune cells that function primarily by producing antibodies. An antibody    is any of the group of proteins that binds specifically to pathogen-associated molecules known as antigens. An antigen    is a chemical structure on the surface of a pathogen that binds to T or B lymphocyte antigen receptors. Once activated by binding to antigen, B cells differentiate into cells that secrete a soluble form of their surface antibodies. These activated B cells are known as plasma cells.

T cells

The T cell    , on the other hand, does not secrete antibody but performs a variety of functions in the adaptive immune response. Different T cell types have the ability to either secrete soluble factors that communicate with other cells of the adaptive immune response or destroy cells infected with intracellular pathogens. The roles of T and B lymphocytes in the adaptive immune response will be discussed further in this chapter.

Plasma cells

Another type of lymphocyte of importance is the plasma cell. A plasma cell    is a B cell that has differentiated in response to antigen binding, and has thereby gained the ability to secrete soluble antibodies. These cells differ in morphology from standard B and T cells in that they contain a large amount of cytoplasm packed with the protein-synthesizing machinery known as rough endoplasmic reticulum.

Natural killer cells

A fourth important lymphocyte is the natural killer cell, a participant in the innate immune response. A natural killer cell (NK)    is a circulating blood cell that contains cytotoxic (cell-killing) granules in its extensive cytoplasm. It shares this mechanism with the cytotoxic T cells of the adaptive immune response. NK cells are among the body’s first lines of defense against viruses and certain types of cancer.

Lymphocytes
Type of lymphocyte Primary function
B lymphocyte Generates diverse antibodies
T lymphocyte Secretes chemical messengers
Plasma cell Secretes antibodies
NK cell Destroys virally infected cells

Visit this website to learn about the many different cell types in the immune system and their very specialized jobs. What is the role of the dendritic cell in an HIV infection?

Primary lymphoid organs and lymphocyte development

Understanding the differentiation and development of B and T cells is critical to the understanding of the adaptive immune response. It is through this process that the body (ideally) learns to destroy only pathogens and leaves the body’s own cells relatively intact. The primary lymphoid organs are the bone marrow and thymus gland. The lymphoid organs are where lymphocytes mature, proliferate, and are selected, which enables them to attack pathogens without harming the cells of the body.

Bone marrow

In the embryo, blood cells are made in the yolk sac. As development proceeds, this function is taken over by the spleen, lymph nodes, and liver. Later, the bone marrow takes over most hematopoietic functions, although the final stages of the differentiation of some cells may take place in other organs. The red bone marrow    is a loose collection of cells where hematopoiesis occurs, and the yellow bone marrow is a site of energy storage, which consists largely of fat cells ( [link] ). The B cell undergoes nearly all of its development in the red bone marrow, whereas the immature T cell, called a thymocyte    , leaves the bone marrow and matures largely in the thymus gland.

Questions & Answers

list down all the hormones secreted by adrenal gland
Odong Reply
The amount of blood pumped by the left ventricle of the heart in one contraction.
Javid Reply
how we can calculate the cardiac output
khater
and how do we calculate the strock valume
khater
stroke volume is not all the blood contained in the left ventricle; normally, only about two-thirds of the blood in the ventricle is expelled with each beat.
Javid
Cardiac output 5.5 l S. V 68.75 ml H. R 80bpm
Javid
If we consider SV 70, end systolic vol is about 15% of total(approx always) out of a total of 80-85 ml only 70ml is pumped per systole
Kartik
what is macrophages?and its function
Sajjad Reply
macrophages they are white blood cells that engulf dead cells in the body
patience
what is power stroke?
muravha
no idea
patience
what is the stroke volume of heart?
up
If an autoimmune disorder targets the alpha cells, production of which hormone would be directly affected?
Samantha Reply
what is a muscle?
Gideon Reply
A band or bundle of fibrous tissue in a human or animal body that has the ability to contract, producing movement in or maintaining the position of parts of the body
Mody
ok
Gideon
what's endolphthamities and panophthalmities?
Gideon
fluid around the brain
louise Reply
what ?
Asif
cerebro spinal fluid
Bhupender
The brain and spinal cord are surrounded by a clear fluid called cerebrospinal fluid (CSF). This fluid is produced and stored in cavities in the brain called ventricles. It circulatesaround the brain, moving from ventricle to ventricle. ... Hydrocephalus is a condition in which there is too much CSF
Archie
what is hydrocphalus
aminul Reply
Google krlena na madarchod yha maa chudwa rha ha sabko notification bhjke
Bhupender
when cerebrospinal fluid produce în the brain, i.e. brain ventricles, is to abundent in the brain and is not trăind out of the brain. as a consequence this lichid pute mechanical pressure oñ the brain and it pushes the cerebrum tissue. as a consequence this pressure on the neuronscan cause neurologi
Centerkinet
cal disfunctions, for example clinical headache
Centerkinet
. It is posible to drainout the fluid through a device dalles shunt,as i remember.
Centerkinet
but where are also home medicinsfor decreasing the production of cerebrospin.fluid etc
Centerkinet
there are some medicines that can decrease the production of csf
Centerkinet
a neurologist advice is needed
Centerkinet
i wrote some medicines NOT home medicines. it is a serious condition and specialized medical advice is needed. of course also general medical knowledge may be helpful, but not enough, a specialist is neede
Centerkinet
if anyone help me in physiology
Radika Reply
i am BSN student of first year which book is best for physiology
Radika
i am BSN student of first year which book is best for physiology
Radika
ross and wilson anotomy and physiology
Sajjad
it's 1 book for anotomy and physiology it's best for bs nursing
Sajjad
yes Ross and wilson physiology is better for study
Nasir
I'm also the student of bs nursing
Sajjad
I study guiton and hall &ganong
Gentle
I'm also midwif help me be the best book for midwif
nimco
what ia the function of indocrine system
sheraz
salam all friend
sheraz
help me with this question; explain at least five emergency acute pain found in fundamental emergency medicine
Christon
Fascial compartment of forearm
Hidayatullah
what's a tissue?
Mwape Reply
a group of cells with the same function
Dee
tissue is a group of cells that perform the same functions.
Rashid
explain a bit about a tissue
Mwape
A tissue is made up of cells that are similar in shape and perform the same function, for instance brain cells form up a brain tissue. Whereas a group of tissues that perform the same function form an organ... so in this case the brain which is the organ is formed as a result of brain tissues.
Isaac
what is gross anatomy
Joseph
the branch of anatomy that deals with the structure of organs and tissues that are visible to the naked eye.
Archie
1.To know how the structures functions. 2.To easily identify the micro structures and the macro structures. 3.To be able to explain that anatomy is the study of the structures and physiology is the study of how the structures functions
Abban Reply
Describe the two classes of hormones (3 with subclasses) and how they affect their target cells.
Shalaeha Reply
what is control centre
Gohil Reply
Angie The larger air passage of the lung is
Angie Reply
guys help to make me understand the structure of the skin
Olokojo Reply
the skin has three layers epidermis,dermis,and subcutaneous tissue
Antony
guys what is esrf
Antony
End Stage of Renal Failure
sheraz
what's the meaning of OPD
Sintung
Out Patient Department
Shahab
the skin has the assesory structures.that is, sebaceous glands, sweat glands, hairs, nails,blood vessels and lymph vessels.
Mutebe
yh
Gideon
define cell and give it's brief description of the orgenelles
Manish Reply
a cell is a basic unit of life
emmanuella
what about philosophy
Smart
the organelle is a membrane bound structure in the cell that performs a particular function
emmanuella
Cell.Is a basic functional unit of life. it has the organelles, Golgi apparatus, smooth endoplasmic membrane, rough endoplasmic reticular,Lysosomes, mitochondrial and others.
Mutebe

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Source:  OpenStax, Anatomy & Physiology. OpenStax CNX. Feb 04, 2016 Download for free at http://legacy.cnx.org/content/col11496/1.8
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