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Ventilation control centers

The control of ventilation is a complex interplay of multiple regions in the brain that signal the muscles used in pulmonary ventilation to contract ( [link] ). The result is typically a rhythmic, consistent ventilation rate that provides the body with sufficient amounts of oxygen, while adequately removing carbon dioxide.

Summary of Ventilation Regulation
System component Function
Medullary respiratory renter Sets the basic rhythm of breathing
Ventral respiratory group (VRG) Generates the breathing rhythm and integrates data coming into the medulla
Dorsal respiratory group (DRG) Integrates input from the stretch receptors and the chemoreceptors in the periphery
Pontine respiratory group (PRG) Influences and modifies the medulla oblongata’s functions
Aortic body Monitors blood PCO 2 , PO 2 , and pH
Carotid body Monitors blood PCO 2 , PO 2 , and pH
Hypothalamus Monitors emotional state and body temperature
Cortical areas of the brain Control voluntary breathing
Proprioceptors Send impulses regarding joint and muscle movements
Pulmonary irritant reflexes Protect the respiratory zones of the system from foreign material
Inflation reflex Protects the lungs from over-inflating

Neurons that innervate the muscles of the respiratory system are responsible for controlling and regulating pulmonary ventilation. The major brain centers involved in pulmonary ventilation are the medulla oblongata and the pontine respiratory group ( [link] ).

Respiratory centers of the brain

The top panel of this image shows the regions of the brain that control respiration. The middle panel shows a magnified view of these regions and links the regions of the brain to the specific organs that they control.

The medulla oblongata contains the dorsal respiratory group (DRG)    and the ventral respiratory group (VRG)    . The DRG is involved in maintaining a constant breathing rhythm by stimulating the diaphragm and intercostal muscles to contract, resulting in inspiration. When activity in the DRG ceases, it no longer stimulates the diaphragm and intercostals to contract, allowing them to relax, resulting in expiration. The VRG is involved in forced breathing, as the neurons in the VRG stimulate the accessory muscles involved in forced breathing to contract, resulting in forced inspiration. The VRG also stimulates the accessory muscles involved in forced expiration to contract.

The second respiratory center of the brain is located within the pons, called the pontine respiratory group, and consists of the apneustic and pneumotaxic centers. The apneustic center    is a double cluster of neuronal cell bodies that stimulate neurons in the DRG, controlling the depth of inspiration, particularly for deep breathing. The pneumotaxic center    is a network of neurons that inhibits the activity of neurons in the DRG, allowing relaxation after inspiration, and thus controlling the overall rate.

Factors that affect the rate and depth of respiration

The respiratory rate and the depth of inspiration are regulated by the medulla oblongata and pons; however, these regions of the brain do so in response to systemic stimuli. It is a dose-response, positive-feedback relationship in which the greater the stimulus, the greater the response. Thus, increasing stimuli results in forced breathing. Multiple systemic factors are involved in stimulating the brain to produce pulmonary ventilation.

Questions & Answers

how are neurons adapted to their function
Namiyaba Reply
machenic support production of blood cells locomotion protection of delicate organs
Ackson Reply
what are hormones?
Ackson
what is anatomy
Juma Reply
what are the functions of bones
Michael
To support and control the movements of the body
Mu
the study of human body is called anatomy
mishra
the study of human body is nt only anatomy but also physiology and histology
Evans
ooops lol I thought Michael was the one with the questions so sorry people. yes anatomy is the study of the body(structure)and it's physiology (functions).
Mu
what are the muscles of respiration?
Dorisha
Hi everyone, Why actyl choline decreases blood pressure although it affects adrenal gland leading it to secret adrenaline and noradrenaline which increase blood pressure?
cholinergic receptors are mostly under Parasympathetic response while adrenergic (norepinephrine) receptors are mostly sympathetic although they are cholinergic adrenergic receptors as well
Ayodeji
vocal cords
MT Reply
musah was admitted to your ward yesterday with traumatic amputation of the right thump . he complained this morning that he has not passed enough urine. Questions. 1) will you consider his complain to be pathological or physiological?. 2) in less than three sentences, justify your opinion. 3) Apply your understanding of the renin- angiotensin-aldosterone system to explain the factors and mechanisms accounting for his complains.
Ellen Reply
the mineral salt which break up a large portion of bone tissue is
Aurora Reply
calcium
Calcium
Sawda
please I need help. musah was admitted to your ward yesterday with traumatic amputation of the right thump. he complained this morning that he has not passed enough urine. Questions. 1). will you consider his complain to be pathological or physiological?.
Ellen
2). In less than three sentences, justify your opinion.
Ellen
Physiological
Ruth
musah copmlan to be physiological because of:-
Juma
cholesterol and triglycerides in simplest terms are fats (lipid) found in blood
Roy Reply
calcium is important for bone density and development. it also helps for safe / normal blood clotting, blood circulation to and from the heart, and muscle movement
Roy
please undertand me action potential ?
Josoph
minimum potential that must be overcomed to cause polarization and stimulate a neuronal response( generate impulse)
Ayodeji
what is muscle tissue
Rifat Reply
the muscle tissue is one of the 4 basic tissues in our body and is responsible for movement of our body
What Is difference between Ovary and Ovum
Sawda
ovary is female reproductive organ while ovum is a female gamete formed from ovary
Ubaidah
Thank You
Sawda
What Is Cholesterol and Triglycerides
Sawda
the mineral salt which break up a large portion of bone tissue
Aurora
in simple way muscle tissue is responsible for movement of our body.
Wellington
Hi Be Home Be safe , how are things doing hope all is well
Natarajan Reply
3 longitudinal bands of smooth muscles found in large intestines
Jamia
what's is sutures
Nimeshka Reply
what would I like to know
Roy Reply
anything u can tell me
Roy
anatomy mins
Manish
when two or more bones meet.
Joseph
Joints
Anita
I am interested in learning but it is a little threatening corona virus covid 19
Samnang Reply
I don't know about Corona virus
Vicky
what would you like to know?
Mbasa
what is a peripheral protien
Ayesha Reply
actually its located in between the lipid layer, it does not specify if it's closer to the inside or the outside of the cell
Justin
It is protein found in lipid bilayer but found attached with Cytoplasm aspect
Jamal
what are the collection of blood.?
sunshine Reply

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Source:  OpenStax, Anatomy & Physiology. OpenStax CNX. Feb 04, 2016 Download for free at http://legacy.cnx.org/content/col11496/1.8
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