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Antidiuretic hormone

Antidiuretic hormone (ADH), also known as vasopressin, is secreted by the cells in the hypothalamus and transported via the hypothalamic-hypophyseal tracts to the posterior pituitary where it is stored until released upon nervous stimulation. The primary trigger prompting the hypothalamus to release ADH is increasing osmolarity of tissue fluid, usually in response to significant loss of blood volume. ADH signals its target cells in the kidneys to reabsorb more water, thus preventing the loss of additional fluid in the urine. This will increase overall fluid levels and help restore blood volume and pressure. In addition, ADH constricts peripheral vessels.

Renin-angiotensin-aldosterone mechanism

The renin-angiotensin-aldosterone mechanism has a major effect upon the cardiovascular system ( [link] ). Renin is an enzyme, although because of its importance in the renin-angiotensin-aldosterone pathway, some sources identify it as a hormone. Specialized cells in the kidneys found in the juxtaglomerular apparatus respond to decreased blood flow by secreting renin into the blood. Renin converts the plasma protein angiotensinogen, which is produced by the liver, into its active form—angiotensin I. Angiotensin I circulates in the blood and is then converted into angiotensin II in the lungs. This reaction is catalyzed by the enzyme angiotensin-converting enzyme (ACE).

Angiotensin II is a powerful vasoconstrictor, greatly increasing blood pressure. It also stimulates the release of ADH and aldosterone, a hormone produced by the adrenal cortex. Aldosterone increases the reabsorption of sodium into the blood by the kidneys. Since water follows sodium, this increases the reabsorption of water. This in turn increases blood volume, raising blood pressure. Angiotensin II also stimulates the thirst center in the hypothalamus, so an individual will likely consume more fluids, again increasing blood volume and pressure.

Hormones involved in renal control of blood pressure

This flow chart shows the action of decreased blood pressure in the short and long term.
In the renin-angiotensin-aldosterone mechanism, increasing angiotensin II will stimulate the production of antidiuretic hormone and aldosterone. In addition to renin, the kidneys produce erythropoietin, which stimulates the production of red blood cells, further increasing blood volume.


Erythropoietin (EPO) is released by the kidneys when blood flow and/or oxygen levels decrease. EPO stimulates the production of erythrocytes within the bone marrow. Erythrocytes are the major formed element of the blood and may contribute 40 percent or more to blood volume, a significant factor of viscosity, resistance, pressure, and flow. In addition, EPO is a vasoconstrictor. Overproduction of EPO or excessive intake of synthetic EPO, often to enhance athletic performance, will increase viscosity, resistance, and pressure, and decrease flow in addition to its contribution as a vasoconstrictor.

Atrial natriuretic hormone

Secreted by cells in the atria of the heart, atrial natriuretic hormone (ANH) (also known as atrial natriuretic peptide) is secreted when blood volume is high enough to cause extreme stretching of the cardiac cells. Cells in the ventricle produce a hormone with similar effects, called B-type natriuretic hormone. Natriuretic hormones are antagonists to angiotensin II. They promote loss of sodium and water from the kidneys, and suppress renin, aldosterone, and ADH production and release. All of these actions promote loss of fluid from the body, so blood volume and blood pressure drop.

Questions & Answers

why rbc is biconcave?
Sudhakar Reply
to carry oxygen easily
What part of the brain controls the body temp
what are epithelial tissues
Sachibu Reply
epithelial tissue that cover overall parts of the body and it's free from blood and nerves
Epithelial tissues are composed of cells laid out in sheets with strong cell-to-cell attachments.
Epithelial tissues perform a variety of functions that include; protection, secretion, filtration, diffusion, absorption, etc.
what control the flow of the blood ?
Donkor Reply
the pumping action of the heart
what is bony promises on the human body
Kelly Reply
what is the bony promises on human body
what are bony prominences on human body
support of the body
what are the characteristics of blood
yeboah Reply
they are red in colour
why blood is red in color?
Me phone no petandi meku doubt vunte nenu phone chesi cheputhanu
Mohan Reply
What is respiratory disease
Rita Reply
What are the importance of homeostasis in human body?
Pablo Reply
it help to keep our salt and water balance
Homeostasis regulates and mentain internal equilibrium (ie temperature and pH) of the body.
maintain temp and ph so our enzyme works properly
The inability of the body regulating and maintaining the temp. and pH results in disease affection.
formation of the bone
Ali Reply
عاوز ايه يعني من الفورمايشن
notes on cell theory and discovery
Masika Reply
Cell theory are a set of rules for overall knowledge on cells. The most famous set of rules include: All cells arise from other cells. The cell is the functional unit of life. The structure (organelles) and morphology of the cell indicates it's main functions.
Antonie Van L. was the first to actually observe alive microorganisms (such as protist and bacteria) in a microscope in the 1600s.
electro phisiology meand
aparna Reply
rouleaux formation factors
Hridya Reply
can anyone suggest me how to learn forearm and hand topic of anatomy?
Anjali Reply
can anyone suggest me how to learn forearm and hand anatomy topic?
can anyone suggest me how to learn forearm and hand topic of anatomy? pls pls tell
check out youtube videos for trickss and while learning the boness part keep the bone wid u and learn ..... hope it helps u
formation of the bone
what is the space between d dura mater and pia mater
Uwakwe Reply
Subdural space
Actually sub dural space is space between dura and arachnoid mater And sub arachnoid space is space between arachnoid and pia mater
the smallest bone in the body
Bahja Reply
stapes is the smallest bone in human Body
what is cell membrane
cell membrane is like a protective cover of a cell and it's cytoplasm
list two adpitive mechanism that control homeostasis condition
positive and negative feedback Mechanism
@Dipayan, a cell membrane encloses and surrounds the cytoplasm of the cell. It's structure varies between species of life (eukaryotes, archaea, bacteria), but it is mostly composed of phospholipid, arachidonic acid, proteins, glycoproteins, glycolipids, and cholesterol.
and the glycoprotein and polysaccharides of the cell membrane forms the glycocalyx which has several functions especially in a bacteria.
homeostatic variables such as body temperature fluctuates within a normal range around the set point, or ideal, for a given homeostatic condition. for example, 98.6°F is a set point for body temperature. The response of the effector determines whether or not the homeostatic variable remains in the n
Chidinma Reply

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