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Squamous cell carcinoma

Squamous cell carcinoma is a cancer that affects the keratinocytes of the stratum spinosum and presents as lesions commonly found on the scalp, ears, and hands ( [link] ). It is the second most common skin cancer. The American Cancer Society reports that two of 10 skin cancers are squamous cell carcinomas, and it is more aggressive than basal cell carcinoma. If not removed, these carcinomas can metastasize. Surgery and radiation are used to cure squamous cell carcinoma.

Squamous cell carcinoma

This photo shows a man’s nose. The squamous cell carcinoma is located just above the tip of the nose and appears as a deep red, irregularly-shaped sore that spans almost the entire bridge of his nose.
Squamous cell carcinoma presents here as a lesion on an individual’s nose. (credit: the National Cancer Institute)

Melanoma

A melanoma    is a cancer characterized by the uncontrolled growth of melanocytes, the pigment-producing cells in the epidermis. Typically, a melanoma develops from a mole. It is the most fatal of all skin cancers, as it is highly metastatic and can be difficult to detect before it has spread to other organs. Melanomas usually appear as asymmetrical brown and black patches with uneven borders and a raised surface ( [link] ). Treatment typically involves surgical excision and immunotherapy.

Melanoma

This photo shows a patch of fair skin containing a large melanoma. The melanoma is black and splotchy in appearance.
Melanomas typically present as large brown or black patches with uneven borders and a raised surface. (credit: the National Cancer Institute)

Doctors often give their patients the following ABCDE mnemonic to help with the diagnosis of early-stage melanoma. If you observe a mole on your body displaying these signs, consult a doctor.

  • A symmetry – the two sides are not symmetrical
  • B orders – the edges are irregular in shape
  • C olor – the color is varied shades of brown or black
  • D iameter – it is larger than 6 mm (0.24 in)
  • E volving – its shape has changed

Some specialists cite the following additional signs for the most serious form, nodular melanoma:

  • E levated – it is raised on the skin surface
  • F irm – it feels hard to the touch
  • G rowing – it is getting larger

Skin disorders

Two common skin disorders are eczema and acne. Eczema is an inflammatory condition and occurs in individuals of all ages. Acne involves the clogging of pores, which can lead to infection and inflammation, and is often seen in adolescents. Other disorders, not discussed here, include seborrheic dermatitis (on the scalp), psoriasis, cold sores, impetigo, scabies, hives, and warts.

Eczema

Eczema is an allergic reaction that manifests as dry, itchy patches of skin that resemble rashes ( [link] ). It may be accompanied by swelling of the skin, flaking, and in severe cases, bleeding. Many who suffer from eczema have antibodies against dust mites in their blood, but the link between eczema and allergy to dust mites has not been proven. Symptoms are usually managed with moisturizers, corticosteroid creams, and immunosuppressants.

Eczema

This photo shows a person with eczema on the ventral skin of the forearms. The person is a Caucasian, but his or her white skin is mottled with many red marks, giving it the appearance of a rash. In some areas, the skin is breaking and peeling.
Eczema is a common skin disorder that presents as a red, flaky rash. (credit: “Jambula”/Wikimedia Commons)

Acne

Acne is a skin disturbance that typically occurs on areas of the skin that are rich in sebaceous glands (face and back). It is most common along with the onset of puberty due to associated hormonal changes, but can also occur in infants and continue into adulthood. Hormones, such as androgens, stimulate the release of sebum. An overproduction and accumulation of sebum along with keratin can block hair follicles. This plug is initially white. The sebum, when oxidized by exposure to air, turns black. Acne results from infection by acne-causing bacteria ( Propionibacterium and Staphylococcus ), which can lead to redness and potential scarring due to the natural wound healing process ( [link] ).

Questions & Answers

what is meant by control center?
Freeman Reply
what is anatomy
Ajibola Reply
is the study of the structure of the body and their relationship to each refers to the shapes iyo sizes
Khadar
what is a blastomere?
Toluba Reply
In biology, a blastomere is a type of cell produced by cleavage (cell division) of the zygote after fertilization and is an essential part of blastula formation.
Adnan
what is cell
Shivaani
Cells are the basic building blocks of all living things. The human body is composed of trillions of cells. They provide structure for the body, take in nutrients from food, convert those nutrients into energy, and carry out specialized functions. ... Cells have many parts, each with a different
Adnan
function
Adnan
cell is a membrane bound unit that contains the fundamentals molecules of life
Sushma
A1
Adnan
excellent
Adnan
movement,reproduction, excretion, respiration ,growth ,nutrition, response to external stimuli.
Sushma
good
Adnan
sister excellent
Adnan
questions pushy ja sukty hy kya
Maryam
jwab forun milta hy ya ak do din k bad
Maryam
Maryam Riaz sister what you say
Adnan
i want to say that k kush questions k answer mil sukty hy mjhy
Maryam
inshallah
Adnan
zaror mere behen
Adnan
question kari
Adnan
hn mil mil sakte h na esly
Ziya
Which muscle of the gluteal region originates from lumber spine? a. Gluteus medius b. Psoas major c. Iliacus d. Gluteus maximus
Maryam
sweet sister's
Adnan
question tu kari Inshallah Allah behtar kariga
Adnan
to mcqs kia to hy
Maryam
answer ni mila abhi
Maryam
wait sister
Adnan
what is the functional unit of kidneys
Khadar
nephron is the functional unit of kidney
Maryam
Maryam Riaz sister option. d. gluteus maximus
Adnan
thanks
Maryam
sorry Maryam Riaz sister
Adnan
option b. psoas major
Adnan
right answer this one
Adnan
nephron is the functional unit of kidney
Ihsan
I discussed with to my teachers
Adnan
d
Ihsan
d. is right option bro
Adnan
yes
Ihsan
what is cell
Shilpa
cell is the smallest unit of life
Maryam
ok
Shilpa
Cells are the basic building blocks of all living things. The human body is composed of trillions of cells. They provide structure for the body, take in nutrients from food, convert those nutrients into energy, and carry out specialized functions. ... Cells have many parts, each with a different
Adnan
function
Adnan
Maryam Riaz sister I m clear option d. also right thank you ihan bro
Adnan
type structure function origin insertion action of muscles
DAMINI Reply
oxygn amount in our body
Tg Reply
A normal level of oxygen is usually 95% or higher. Some people with chronic lung disease or sleep apnea can have normal levels around 90%. The “SpO2” reading on a pulse oximeter shows the percentage of oxygen in someone's blood
Adnan
What is the difference between cytoplasmic and endoplasmic
Ajibola Reply
The cytoplasm is 90℅ water and 10℅ of organic and inorganic compounds. The cytoplasm contains mitochondria. ... Lysosomes of Cytoplasm contains 50 different enzymes that digest proteins, lipids, and nucleic acids. The endoplasmic reticulum produces process and transport proteins, lipids for all the
Adnan
tarsal are cube shaped broad and long whiles metatarsal they are longer than they are wide
Priscilla Reply
articular cartilage serve as shock absorber and also reduces friction
Priscilla
articular cartilage serve as shock absorber and also reduces friction
Priscilla
when a bone joint with another bone
Priscilla
to know how you body function to know the relationship between the body parts to know specific functions of a certain body parts
romeo Reply
To know our body function we shd know chemical secretion of our glands, we can map all the function of our body and also relation ship between the body parts.
KUSUMA
that z it kusuma
kanaku
can you get fungi infection by seating on a public toilet?
Calls Reply
explain how blood acts as a connective tissue in the body
Rymz Reply
how does blood act as a connective tissue in the body
Rymz
what is anatomy
Victoriah Reply
fat deficiency in the body
Agbor Reply
Explain how body exercise regulates blood pressure
dranimva Reply
thank you
Thelma
what is cillia and flangella
Kalah Reply
what are the proceduers of condactive system ?
Salua Reply

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Source:  OpenStax, Anatomy & Physiology. OpenStax CNX. Feb 04, 2016 Download for free at http://legacy.cnx.org/content/col11496/1.8
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