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Squamous cell carcinoma

Squamous cell carcinoma is a cancer that affects the keratinocytes of the stratum spinosum and presents as lesions commonly found on the scalp, ears, and hands ( [link] ). It is the second most common skin cancer. The American Cancer Society reports that two of 10 skin cancers are squamous cell carcinomas, and it is more aggressive than basal cell carcinoma. If not removed, these carcinomas can metastasize. Surgery and radiation are used to cure squamous cell carcinoma.

Squamous cell carcinoma

This photo shows a man’s nose. The squamous cell carcinoma is located just above the tip of the nose and appears as a deep red, irregularly-shaped sore that spans almost the entire bridge of his nose.
Squamous cell carcinoma presents here as a lesion on an individual’s nose. (credit: the National Cancer Institute)

Melanoma

A melanoma    is a cancer characterized by the uncontrolled growth of melanocytes, the pigment-producing cells in the epidermis. Typically, a melanoma develops from a mole. It is the most fatal of all skin cancers, as it is highly metastatic and can be difficult to detect before it has spread to other organs. Melanomas usually appear as asymmetrical brown and black patches with uneven borders and a raised surface ( [link] ). Treatment typically involves surgical excision and immunotherapy.

Melanoma

This photo shows a patch of fair skin containing a large melanoma. The melanoma is black and splotchy in appearance.
Melanomas typically present as large brown or black patches with uneven borders and a raised surface. (credit: the National Cancer Institute)

Doctors often give their patients the following ABCDE mnemonic to help with the diagnosis of early-stage melanoma. If you observe a mole on your body displaying these signs, consult a doctor.

  • A symmetry – the two sides are not symmetrical
  • B orders – the edges are irregular in shape
  • C olor – the color is varied shades of brown or black
  • D iameter – it is larger than 6 mm (0.24 in)
  • E volving – its shape has changed

Some specialists cite the following additional signs for the most serious form, nodular melanoma:

  • E levated – it is raised on the skin surface
  • F irm – it feels hard to the touch
  • G rowing – it is getting larger

Skin disorders

Two common skin disorders are eczema and acne. Eczema is an inflammatory condition and occurs in individuals of all ages. Acne involves the clogging of pores, which can lead to infection and inflammation, and is often seen in adolescents. Other disorders, not discussed here, include seborrheic dermatitis (on the scalp), psoriasis, cold sores, impetigo, scabies, hives, and warts.

Eczema

Eczema is an allergic reaction that manifests as dry, itchy patches of skin that resemble rashes ( [link] ). It may be accompanied by swelling of the skin, flaking, and in severe cases, bleeding. Many who suffer from eczema have antibodies against dust mites in their blood, but the link between eczema and allergy to dust mites has not been proven. Symptoms are usually managed with moisturizers, corticosteroid creams, and immunosuppressants.

Eczema

This photo shows a person with eczema on the ventral skin of the forearms. The person is a Caucasian, but his or her white skin is mottled with many red marks, giving it the appearance of a rash. In some areas, the skin is breaking and peeling.
Eczema is a common skin disorder that presents as a red, flaky rash. (credit: “Jambula”/Wikimedia Commons)

Acne

Acne is a skin disturbance that typically occurs on areas of the skin that are rich in sebaceous glands (face and back). It is most common along with the onset of puberty due to associated hormonal changes, but can also occur in infants and continue into adulthood. Hormones, such as androgens, stimulate the release of sebum. An overproduction and accumulation of sebum along with keratin can block hair follicles. This plug is initially white. The sebum, when oxidized by exposure to air, turns black. Acne results from infection by acne-causing bacteria ( Propionibacterium and Staphylococcus ), which can lead to redness and potential scarring due to the natural wound healing process ( [link] ).

Questions & Answers

what is pelvis
Aisha Reply
Complex of bones that connect the trunk and the legs,supports and balance the trunk.
Orpha
What is d most heaviest organ in d body
Abraham Reply
Liver
Akasi
The skin
Akasi
skin
Divya
why skin?
Sam
liver
Anne
water
Mehdi
Heart
Biplob
the brain
lehumo
skin
Emma
skin
jessica
largest internal organ is the liver
jessica
liver is the heaviest organ
Eyyammeh
the liver is the heaviest organs
Khh
What is the meaning? What does it entails to? What are the works of Arthropologists?
Orpha Reply
bones of appendicular skeleton
hemalatha Reply
Fore limbs, hind limbs, pectoral and pelvic girdle
Abraham
Functions of the thoracic cage
Fereh Reply
protect all the organs and tissues from any impact or injury
Javier
It protects the heart other tissues in the chest region
Abraham
why sickle cell carrier people don't get malaria
Boakye Reply
Bcos mosquitoes are not attracted by their blood due to poor oxygen
Abraham
What is the amniotic fluid
bollywood Reply
amniotic fluid is the fluid that is inside the uterus with the baby.
Fati
shielded
Varun
This fluid serves as a cushion for the growing fetus but also serves to facilitate the exchange of nutrients, water, and biochemical products between mother and fetus.
Anne
it also reduces friction during birth as it wets the birth canal during delivery
steve
structure of heart and it's function (10 mark )
Priyanka Reply
not possible
Abraham
What is the best book on physiology?
cesar Reply
describe varicocele
malulu
what do you mean by peritoneum
Siba Reply
It is thick covering surrounding the abdomen
Awais
r8
how to become good in Anatomy and physiology
malulu
hi
Milkah
hlo
Wani
What are is the last solution to abdomen pain in pregnant women
Umoru
no it is in kidney
Tantray
Kk
Umoru
structure of heart and it's function
Priyanka
Serous membrane lining the cavity of the abdomen
bollywood
it is four lobs structure and it is triangular in shaped. it 's function pumping the blood
ABDULLAH
explain root of lungs
ABDULLAH
Glomerular pressure -capsule pressure -colloid osmosis pressure
malulu Reply
how to describe mechanism of micturition
malulu
spleen is important?
AKASH Reply
helpful in destruction of rbc
It is imp in storing blood and destruction of microbes and harmful particles
Awais
ty sir
AKASH
K
Umoru
what are the sources of glucose in the body
malulu
describe mechanism of micturition
malulu
Pancreatic hormones with function
mami Reply
Insulin, which helps to regulate our blood sugar levels.
Bb
glucagon which is antagonistic to insulin increase the blood glucose level,. Somatostatin help to regulate the levels of both insulin and glucagon
Ashish
thnks for helping
nimco
thanks
Narendra
what is a lymph node.?
AKASH
lymph nodes are small kidney shaped organs of the lymphatic system.
Trishauna
there are several hundred lymph nodes found mostly throughout the thorax and abdomen of the body with the highest concentrations in the auxiliary (armpit) and inguinal groin regions.
Trishauna
what is life
Yar Reply
life is the existence of an individual human being animal or plant
Furmose
how I join this
Ahmed
meaning
Furmose
to day I am new person and I can't participate questions so to morow I shall participate question sopleas excuse me
Ahmed
I had a debate earlier about nutrition and it didn't get a clear answer on that,can one tell me what the definition of nutrition.?
kelvin
the nutrition is nourish person is feeling an nutrition
Ahmed
I think nutrition is the process of taking food and using it for growth, metabolism and repair.
Methila
life is full of happy and sorrow
Sanamacha
life is achievement
Nandini
life is the nothing but god gave us 1 body. and we all service k in this body. The things which we do for the Survivation for this body I felt that this is called as the life
AKASH
Yes God gave us life but not god who gave us the life. Hope u understood what i meant by God n not god who gave life..... ?
laku
What's the question?
Sherman Reply

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Source:  OpenStax, Anatomy & Physiology. OpenStax CNX. Feb 04, 2016 Download for free at http://legacy.cnx.org/content/col11496/1.8
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