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By the end of this section, you will be able to:
  • Discuss the mechanisms involved in the neural regulation of vascular homeostasis
  • Describe the contribution of a variety of hormones to the renal regulation of blood pressure
  • Identify the effects of exercise on vascular homeostasis
  • Discuss how hypertension, hemorrhage, and circulatory shock affect vascular health

In order to maintain homeostasis in the cardiovascular system and provide adequate blood to the tissues, blood flow must be redirected continually to the tissues as they become more active. In a very real sense, the cardiovascular system engages in resource allocation, because there is not enough blood flow to distribute blood equally to all tissues simultaneously. For example, when an individual is exercising, more blood will be directed to skeletal muscles, the heart, and the lungs. Following a meal, more blood is directed to the digestive system. Only the brain receives a more or less constant supply of blood whether you are active, resting, thinking, or engaged in any other activity.

[link] provides the distribution of systemic blood at rest and during exercise. Although most of the data appears logical, the values for the distribution of blood to the integument may seem surprising. During exercise, the body distributes more blood to the body surface where it can dissipate the excess heat generated by increased activity into the environment.

Systemic Blood Flow During Rest, Mild Exercise, and Maximal Exercise in a Healthy Young Individual
Organ Resting
(mL/min)
Mild exercise
(mL/min)
Maximal exercise
(mL/min)
Skeletal muscle 1200 4500 12,500
Heart 250 350 750
Brain 750 750 750
Integument 500 1500 1900
Kidney 1100 900 600
Gastrointestinal 1400 1100 600
Others
(i.e., liver, spleen)
600 400 400
Total 5800 9500 17,500

Three homeostatic mechanisms ensure adequate blood flow, blood pressure, distribution, and ultimately perfusion: neural, endocrine, and autoregulatory mechanisms. They are summarized in [link] .

Summary of factors maintaining vascular homeostasis

This flowchart shows the various factors that control the flow of blood. The top panel focuses on autoregulation, and the bottom panel focuses on neural and endocrine mechanisms.
Adequate blood flow, blood pressure, distribution, and perfusion involve autoregulatory, neural, and endocrine mechanisms.

Neural regulation

The nervous system plays a critical role in the regulation of vascular homeostasis. The primary regulatory sites include the cardiovascular centers in the brain that control both cardiac and vascular functions. In addition, more generalized neural responses from the limbic system and the autonomic nervous system are factors.

The cardiovascular centers in the brain

Neurological regulation of blood pressure and flow depends on the cardiovascular centers located in the medulla oblongata. This cluster of neurons responds to changes in blood pressure as well as blood concentrations of oxygen, carbon dioxide, and hydrogen ions. The cardiovascular center contains three distinct paired components:

  • The cardioaccelerator centers stimulate cardiac function by regulating heart rate and stroke volume via sympathetic stimulation from the cardiac accelerator nerve.
  • The cardioinhibitor centers slow cardiac function by decreasing heart rate and stroke volume via parasympathetic stimulation from the vagus nerve.
  • The vasomotor centers control vessel tone or contraction of the smooth muscle in the tunica media. Changes in diameter affect peripheral resistance, pressure, and flow, which affect cardiac output. The majority of these neurons act via the release of the neurotransmitter norepinephrine from sympathetic neurons.

Questions & Answers

why sickle cell carrier people don't get malaria
Boakye Reply
What is the amniotic fluid
bollywood Reply
structure of heart and it's function (10 mark )
Priyanka Reply
What is the best book on physiology?
cesar Reply
describe varicocele
malulu
what do you mean by peritoneum
Siba Reply
It is thick covering surrounding the abdomen
Awais
r8
how to become good in Anatomy and physiology
malulu
hi
Milkah
hlo
Wani
What are is the last solution to abdomen pain in pregnant women
Umoru
no it is in kidney
Tantray
Kk
Umoru
structure of heart and it's function
Priyanka
Serous membrane lining the cavity of the abdomen
bollywood
it is four lobs structure and it is triangular in shaped. it 's function pumping the blood
ABDULLAH
explain root of lungs
ABDULLAH
Glomerular pressure -capsule pressure -colloid osmosis pressure
malulu Reply
how to describe mechanism of micturition
malulu
spleen is important?
AKASH Reply
helpful in destruction of rbc
It is imp in storing blood and destruction of microbes and harmful particles
Awais
ty sir
AKASH
K
Umoru
what are the sources of glucose in the body
malulu
describe mechanism of micturition
malulu
Pancreatic hormones with function
mami Reply
Insulin, which helps to regulate our blood sugar levels.
Bb
glucagon which is antagonistic to insulin increase the blood glucose level,. Somatostatin help to regulate the levels of both insulin and glucagon
Ashish
thnks for helping
nimco
thanks
Narendra
what is a lymph node.?
AKASH
lymph nodes are small kidney shaped organs of the lymphatic system.
Trishauna
there are several hundred lymph nodes found mostly throughout the thorax and abdomen of the body with the highest concentrations in the auxiliary (armpit) and inguinal groin regions.
Trishauna
what is life
Yar Reply
life is the existence of an individual human being animal or plant
Furmose
how I join this
Ahmed
meaning
Furmose
to day I am new person and I can't participate questions so to morow I shall participate question sopleas excuse me
Ahmed
I had a debate earlier about nutrition and it didn't get a clear answer on that,can one tell me what the definition of nutrition.?
kelvin
the nutrition is nourish person is feeling an nutrition
Ahmed
I think nutrition is the process of taking food and using it for growth, metabolism and repair.
Methila
life is full of happy and sorrow
Sanamacha
life is achievement
Nandini
life is the nothing but god gave us 1 body. and we all service k in this body. The things which we do for the Survivation for this body I felt that this is called as the life
AKASH
Yes God gave us life but not god who gave us the life. Hope u understood what i meant by God n not god who gave life..... ?
laku
What's the question?
Sherman Reply
once you lose pigmentation can you ever get it back
Shannon Reply
s
Nandini
females are lesser prone to acne
Ritika Reply
why please expain
Janvi
described the skin
Yayra Reply
skin is outer covery of human body and it is largest organ of human body. it do three fauntion protection regulation and sensation of human body that is men fauntion of human skin it has seven part.
ABDULLAH
how thick is the epidermis?
Sovilace
the integumentary system is the largest system of the body 16% of body weight and 1.5 to 2m² in area
Trishauna
function of the endocrine system
Hamo Reply
produces hormones that plays specific functions
has endocrine gland calld as ductless gland so as produces hormones
why is it important to view the body a as whole
Ileana Reply
mind body and soul to be in a whole of the spirit
Ameida

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Source:  OpenStax, Anatomy & Physiology. OpenStax CNX. Feb 04, 2016 Download for free at http://legacy.cnx.org/content/col11496/1.8
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