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By the end of this section, you will be able to:
  • Identify the most important hormones produced by the testes and ovaries
  • Name the hormones produced by the placenta and state their functions

This section briefly discusses the hormonal role of the gonads—the male testes and female ovaries—which produce the sex cells (sperm and ova) and secrete the gonadal hormones. The roles of the gonadotropins released from the anterior pituitary (FSH and LH) were discussed earlier.

The primary hormone produced by the male testes is testosterone    , a steroid hormone important in the development of the male reproductive system, the maturation of sperm cells, and the development of male secondary sex characteristics such as a deepened voice, body hair, and increased muscle mass. Interestingly, testosterone is also produced in the female ovaries, but at a much reduced level. In addition, the testes produce the peptide hormone inhibin    , which inhibits the secretion of FSH from the anterior pituitary gland. FSH stimulates spermatogenesis.

The primary hormones produced by the ovaries are estrogens    , which include estradiol, estriol, and estrone. Estrogens play an important role in a larger number of physiological processes, including the development of the female reproductive system, regulation of the menstrual cycle, the development of female secondary sex characteristics such as increased adipose tissue and the development of breast tissue, and the maintenance of pregnancy. Another significant ovarian hormone is progesterone    , which contributes to regulation of the menstrual cycle and is important in preparing the body for pregnancy as well as maintaining pregnancy. In addition, the granulosa cells of the ovarian follicles produce inhibin, which—as in males—inhibits the secretion of FSH.During the initial stages of pregnancy, an organ called the placenta develops within the uterus. The placenta supplies oxygen and nutrients to the fetus, excretes waste products, and produces and secretes estrogens and progesterone. The placenta produces human chorionic gonadotropin (hCG) as well. The hCG hormone promotes progesterone synthesis and reduces the mother’s immune function to protect the fetus from immune rejection. It also secretes human placental lactogen (hPL), which plays a role in preparing the breasts for lactation, and relaxin, which is thought to help soften and widen the pubic symphysis in preparation for childbirth. The hormones controlling reproduction are summarized in [link] .

Reproductive Hormones
Gonad Associated hormones Chemical class Effect
Testes Testosterone Steroid Stimulates development of male secondary sex characteristics and sperm production
Testes Inhibin Protein Inhibits FSH release from pituitary
Ovaries Estrogens and progesterone Steroid Stimulate development of female secondary sex characteristics and prepare the body for childbirth
Placenta Human chorionic gonadotropin Protein Promotes progesterone synthesis during pregnancy and inhibits immune response against fetus

Everyday connections

Anabolic steroids

The endocrine system can be exploited for illegal or unethical purposes. A prominent example of this is the use of steroid drugs by professional athletes.

Commonly used for performance enhancement, anabolic steroids are synthetic versions of the male sex hormone, testosterone. By boosting natural levels of this hormone, athletes experience increased muscle mass. Synthetic versions of human growth hormone are also used to build muscle mass.

The use of performance-enhancing drugs is banned by all major collegiate and professional sports organizations in the United States because they impart an unfair advantage to athletes who take them. In addition, the drugs can cause significant and dangerous side effects. For example, anabolic steroid use can increase cholesterol levels, raise blood pressure, and damage the liver. Altered testosterone levels (both too low or too high) have been implicated in causing structural damage to the heart, and increasing the risk for cardiac arrhythmias, heart attacks, congestive heart failure, and sudden death. Paradoxically, steroids can have a feminizing effect in males, including shriveled testicles and enlarged breast tissue. In females, their use can cause masculinizing effects such as an enlarged clitoris and growth of facial hair. In both sexes, their use can promote increased aggression (commonly known as “roid-rage”), depression, sleep disturbances, severe acne, and infertility.

Chapter review

The male and female reproductive system is regulated by follicle-stimulating hormone (FSH) and luteinizing hormone (LH) produced by the anterior lobe of the pituitary gland in response to gonadotropin-releasing hormone (GnRH) from the hypothalamus. In males, FSH stimulates sperm maturation, which is inhibited by the hormone inhibin. The steroid hormone testosterone, a type of androgen, is released in response to LH and is responsible for the maturation and maintenance of the male reproductive system, as well as the development of male secondary sex characteristics. In females, FSH promotes egg maturation and LH signals the secretion of the female sex hormones, the estrogens and progesterone. Both of these hormones are important in the development and maintenance of the female reproductive system, as well as maintaining pregnancy. The placenta develops during early pregnancy, and secretes several hormones important for maintaining the pregnancy.

Questions & Answers

what is oesophagus?
Bhavani Reply
oesophagus also known as food pip
ABDULLAH
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Beryl Reply
what's the meaning of polar?
Jackson Reply
Sign of anaemia or whitish color or Hgb luck
Kassahn
Are you talking of Polar anaemia or what, because the word polar doesnt have one meaning
Kingsley
what are the three types of adrenocorticoids hormones
Lubega Reply
glucocorticoids mineralocorticoid and catecholamines
Kartik
what is polar and non-polar
Jackson Reply
polar unequal share of electron while non polar is equal share
Quran
why are phosphate molecules negatively charged?
Jackson Reply
Bocz of unpaired elections
Javid
because of unpaired electrons
ABDULLAH
what are amphipathic molecules?
Jackson Reply
Amphipathic molecules are molecules with both polar and non polar regions
Mohammed
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MADUBULA Reply
Hw does the male organ develop
MADUBULA
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Aliyu
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Rugut Reply
it is an imagency condition resulting from abnormal and immediate alagic response to a substance to which the body has become intensively sensitized
Lubega
different between drug and medicine
ado Reply
drugs have no medical application (cocaine, heroin, crystal meth). medicine have medical purpose (fentanyl, albuterol, aspirin, ect ect)
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Sidra
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Zwanga Reply
what are the smooth muscles of the heart
Sintung Reply
stomach
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kidney weight on males?
saba
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O-olfactory O-optic O-occumulator T-trochlear T-trigemenal A-abducent F-facial A-auditory G-glossopharyngeal V-vagus A-acessory
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Read KD Tripathi book of Pharmacology.
mayank
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mayank
CT Scan means
Sintung
what's health?
Sintung
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Philip
hi
Sintung
CT means - computerized tomography
Vivek
connective tissue
Dee
they link some body organs
Sintung
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saba
what is tomography?
Gideon
tomography ☝
shahid
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how hemolytic anemia cause due to gas gangrene?
Huma Reply
what's gangrene?
Sidra
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Source:  OpenStax, Anatomy & Physiology. OpenStax CNX. Feb 04, 2016 Download for free at http://legacy.cnx.org/content/col11496/1.8
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