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By the end of this section, you will be able to:
  • Describe a dense body
  • Explain how smooth muscle works with internal organs and passageways through the body
  • Explain how smooth muscles differ from skeletal and cardiac muscles
  • Explain the difference between single-unit and multi-unit smooth muscle

Smooth muscle (so-named because the cells do not have striations) is present in the walls of hollow organs like the urinary bladder, uterus, stomach, intestines, and in the walls of passageways, such as the arteries and veins of the circulatory system, and the tracts of the respiratory, urinary, and reproductive systems ( [link] ab ). Smooth muscle is also present in the eyes, where it functions to change the size of the iris and alter the shape of the lens; and in the skin where it causes hair to stand erect in response to cold temperature or fear.

Smooth muscle tissue

This diagram shows the structure of smooth muscle. To the left of the figure, a small diagram of the stomach is shown. To its immediate right, a magnified view of the muscle fibers are shown and a further magnification highlights the structure of these cells. Below these drawings is a micrograph showing smooth muscle tissue cells.
Smooth muscle tissue is found around organs in the digestive, respiratory, reproductive tracts and the iris of the eye. LM × 1600. (Micrograph provided by the Regents of University of Michigan Medical School © 2012)

View the University of Michigan WebScope at (External Link) to explore the tissue sample in greater detail.

Smooth muscle fibers are spindle-shaped (wide in the middle and tapered at both ends, somewhat like a football) and have a single nucleus; they range from about 30 to 200 μ m (thousands of times shorter than skeletal muscle fibers), and they produce their own connective tissue, endomysium. Although they do not have striations and sarcomeres, smooth muscle fibers do have actin and myosin contractile proteins, and thick and thin filaments. These thin filaments are anchored by dense bodies. A dense body    is analogous to the Z-discs of skeletal and cardiac muscle fibers and is fastened to the sarcolemma. Calcium ions are supplied by the SR in the fibers and by sequestration from the extracellular fluid through membrane indentations called calveoli.

Because smooth muscle cells do not contain troponin, cross-bridge formation is not regulated by the troponin-tropomyosin complex but instead by the regulatory protein calmodulin    . In a smooth muscle fiber, external Ca ++ ions passing through opened calcium channels in the sarcolemma, and additional Ca ++ released from SR, bind to calmodulin. The Ca ++ -calmodulin complex then activates an enzyme called myosin (light chain) kinase, which, in turn, activates the myosin heads by phosphorylating them (converting ATP to ADP and P i , with the P i attaching to the head). The heads can then attach to actin-binding sites and pull on the thin filaments. The thin filaments also are anchored to the dense bodies; the structures invested in the inner membrane of the sarcolemma (at adherens junctions) that also have cord-like intermediate filaments attached to them. When the thin filaments slide past the thick filaments, they pull on the dense bodies, structures tethered to the sarcolemma, which then pull on the intermediate filaments networks throughout the sarcoplasm. This arrangement causes the entire muscle fiber to contract in a manner whereby the ends are pulled toward the center, causing the midsection to bulge in a corkscrew motion ( [link] ).

Questions & Answers

what is oesophagus?
Bhavani Reply
oesophagus also known as food pip
ABDULLAH
What is the meaning of dissection
Beryl Reply
what's the meaning of polar?
Jackson Reply
Sign of anaemia or whitish color or Hgb luck
Kassahn
Are you talking of Polar anaemia or what, because the word polar doesnt have one meaning
Kingsley
what are the three types of adrenocorticoids hormones
Lubega Reply
glucocorticoids mineralocorticoid and catecholamines
Kartik
what is polar and non-polar
Jackson Reply
polar unequal share of electron while non polar is equal share
Quran
why are phosphate molecules negatively charged?
Jackson Reply
Bocz of unpaired elections
Javid
because of unpaired electrons
ABDULLAH
what are amphipathic molecules?
Jackson Reply
Amphipathic molecules are molecules with both polar and non polar regions
Mohammed
How does the male organ develop
MADUBULA Reply
Hw does the male organ develop
MADUBULA
Review your questions madam
Aliyu
what is anaphylaxis?
Rugut Reply
it is an imagency condition resulting from abnormal and immediate alagic response to a substance to which the body has become intensively sensitized
Lubega
different between drug and medicine
ado Reply
drugs have no medical application (cocaine, heroin, crystal meth). medicine have medical purpose (fentanyl, albuterol, aspirin, ect ect)
Jordan
medicine is a substance or preparation used in treating disease,drug is chemical compound medicine are drugs but all drugs are not medicines
Wafa
assalam o alaikum
Sidra
what happen to ECF and ICF regarding to OEDEMA
Zwanga Reply
what are the smooth muscles of the heart
Sintung Reply
stomach
Sidra
identify external features of kidney
saba Reply
kidney weight on males?
saba
and female ?
saba
Sle full name & treatment
Samim
Syplymic lupw erythematous
Samim
blood supply to spleen ?
saba
g..
saba
ya 135 g females
saba
130 on male
saba
130g on male
saba
g samim
saba
no 130grms on male
saba
mbbs
saba
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Shahab
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saba
your name?
saba
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tum kya krti ho? muskan
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Shahab
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saba
Define cranial nerves with oder
Javid
O-olfactory O-optic O-occumulator T-trochlear T-trigemenal A-abducent F-facial A-auditory G-glossopharyngeal V-vagus A-acessory
Aniee
opd mean?
Shahab
out patient department
mahesh
thnxx
Shahab
Ty Aniee singh
Javid
Ap sb us book s parhte h
Areeej
Read KD Tripathi book of Pharmacology.
mayank
Hello
mayank
CT Scan means
Sintung
what's health?
Sintung
hello
Philip
hi
Sintung
CT means - computerized tomography
Vivek
connective tissue
Dee
they link some body organs
Sintung
Difference between drug and medicine
Javid
hiii muskan
saba
what is tomography?
Gideon
tomography ☝
shahid
yes
Gideon
how hemolytic anemia cause due to gas gangrene?
Huma Reply
what's gangrene?
Sidra
why retro abdominal region called or named "flank "?
Huma Reply

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Source:  OpenStax, Anatomy & Physiology. OpenStax CNX. Feb 04, 2016 Download for free at http://legacy.cnx.org/content/col11496/1.8
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