• Card 12 / 34: A 25 year-old man comes to your office complaining of frequent bloating, gas, and diarrhea. His diarrhea is non-bloody and he has no associated fevers nor has he lost weight. Stool specimens checked for various infectious organisms all return negative. He notes that his symptoms typically occur shortly after eating ice cream or cheese pizza. You check stool sodium and potassium concentration and calculate the fecal osmotic gap. Which of the following results for the fecal osmotic gap would you most likely find in this patient?
    1.) 75 mosm/kg H20
    2.) 25 mosm/kg H20
    3.) 140 mosm/kg H20
    4.) 55 mosm/kg H20
    5.) 100 mosm/kg H20

    Answer:
    3.) 140 mosm/kg H20

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Explanation:

Case of lactose intolerance. Causes osmotic diarrhea. Fecal osmotic gap wide (usually greater than 125) due to relatively lower concentration of sodium and potassium in stool.

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Gastrointestinal Pathophysiology Self-Assessment

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Access: Public

Attribution:  Laurence Scott Bailen, Tamsin Knox, Paul Abourjaily, Fredric D. Gordon,Marshall Kaplan,Andrew G. Plaut. PPY 222 Gastrointestinal Pathophysiology, Spring 2007. (Tufts University OpenCourseWare), http://ocw.tufts.edu/Course/47 (Accessed 3 May, 2014). License: Creative Commons BY-NC-SA
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